Results 101 to 110 of about 401,272 (328)

Harnessing Non‐Covalent Protein–Protein Interaction Domains for Production of Biocatalytic Materials Systems

open access: yesAdvanced Functional Materials, EarlyView.
Non‐covalent protein–protein interactions mediated by SH3, PDZ, or GBD domains enable the self‐assembly of stable and biocatalytically active hydrogel materials. These soft materials can be processed into monodisperse foams that, once dried, exhibit enhanced mechanical stability and activity and are easily integrated into microstructured flow ...
Julian S. Hertel   +5 more
wiley   +1 more source

Influence of a fluorobenzene nucleobase analogue on the conformational flexibility of RNA studied by molecular dynamics simulations [PDF]

open access: yes, 2006
Chemically modified bases are frequently used to stabilize nucleic acids, to study the driving forces for nucleic acid structure formation and to tune DNA and RNA hybridization conditions.
Engels, Joachim W. (Prof. Dr.)   +1 more
core  

Novel Drug‐Testing Platform for Vascular Injury‐induced Intimal Hyperplasia Using a Microphysiological System

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops a 3D vascular injury model using a microphysiological system that mimics key features of intimal hyperplasia. Antiproliferative drugs reduced VSMC proliferation but worsened endothelialdenudation. A combination of diphenyleneiodonium and quercetin effectively reduced proliferation and migration of VSMC and inflammation while ...
Ungsig Nam   +7 more
wiley   +1 more source

Abundant Z-cyanomethanimine in the interstellar medium: paving the way to the synthesis of adenine

open access: yes, 2018
We report the first detection in the interstellar medium of the Z-isomer of cyanomethanimine (HNCHCN), an HCN dimer proposed as precursor of adenine. We identified six transitions of Z-cyanomethanimine, along with five transitions of E-cyanomethanimine ...
Aladro, R.   +8 more
core   +1 more source

Multienzyme (3‐in‐1)‐Mimicking a Single Nucleobase‐Derived Bionanozyme for Versatile Environmental and Biomedical Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reports the development of bioinspired 2D crystalline Bionanozyme derived from a single nucleobase. It effectively mimics multienzyme activity to detect and remove phenolic pollutants, identify disease biomarkers with high sensitivity, and protect cells from oxidative stress.
Subrat Vishwakarma   +8 more
wiley   +1 more source

Fox grape cv. Bordô (Vitis labrusca L.) and grapevine cv. Chardonnay (Vitis vinifera L.) cultivated in vitro under different carbohydrates, amino acids and 6-Benzylaminopurine levels

open access: yesBrazilian Archives of Biology and Technology, 2013
The aim of this work was to study the influence of sucrose and glucose, amino acids and BAP (6-Benzylaminopurine) levels on in vitro shoot regeneration of fox grape cv. Bordô and grapevine cv. Chardonnay.
Dayse Cristina de Carvalho   +5 more
doaj  

Dysregulation of NAD+ metabolism induces a Schwann cell dedifferentiation program [PDF]

open access: yes, 2018
The Schwann cell (SC) is the major component of the peripheral nervous system (PNS) that provides metabolic and functional support for peripheral axons. The emerging roles of SC mitochondrial function for PNS development and axonal stability indicate the
Hackett, Amber R   +4 more
core   +1 more source

Human Skin Models in Biophotonics: Materials, Methods, and Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses how the optical properties of human skin can be replicated in human skin models. It describes the principles, materials, and techniques used to develop artificial skin for biophotonics research. Finally, the article highlights recent advances and shows how these models improve the study of light‐skin interactions without the need ...
Dardan Bajrami   +4 more
wiley   +1 more source

Two New Constituents from Artemisia capillaris Thunb.

open access: yesMolecules, 2008
Two new compounds, 6′-O-caffeoyl-p-hydroxyacetophenone-4-O-β-D-glucopyranoside(1) and 6-amino-9-[1-(3,4-dihydroxyphenyl)ethyl]-9H-purine (2) wereisolated from the aerial parts of Artemisia capillaris Thunb.
Yue-Hu Pei   +4 more
doaj   +1 more source

Poly(hydroxy‐oxazolidone) Thermoplastic Elastomers for Safer, Greener and Customizable Blood‐Contacting Medical Devices

open access: yesAdvanced Healthcare Materials, EarlyView.
A poly(hydroxy‐oxazolidone) (PHOx) is synthesized from CO2‐based precursors, enabling the up‐cycling of this waste material. After synthesis, PHOx shows thermoplastic properties, and can therefore be processed by many temperature‐dependent techniques. PHOx is hemocompatible, anti‐adhesive, and biocompatible, which is demonstrated in vitro and in vivo ...
Sofia F. Melo   +11 more
wiley   +1 more source

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