Results 141 to 150 of about 401,272 (328)
Total Synthesis of Flavin-adenine-dinucleotide [PDF]
, 1952 Stuart M. H. Christie +2 more
openalex +1 more source
Advanced Science, EarlyView.The co‐delivery of mRNAs encoding a CD47 inhibitor and a cytokine cocktail (interleukins 12, 15, and 21) via lipid nanoparticles enables effective localized immunotherapy. This strategy not only suppresses tumor progression but also enhances type 1 conventional dendritic cell (cDC1) differentiation and activates CD8+ T cells, thereby inducing robust ...
Tao Jiang +14 more
wiley +1 more source
A Two‐Protein Chemoreceptor Complex Regulates Oxygen Thresholds in Bacterial Magneto‐Aerotaxis
Advanced Science, EarlyView.Magnetotactic bacteria align with Earth's magnetic field, helping them migrate toward low‐oxygen environments. This study reveals how Magnetospirillum gryphiswaldense uses a specialized flavin adenine dinucleotide (FAD)‐dependent chemoreceptor, composed of two interacting proteins, for precise navigation in oxygen gradients.
Julian Herz +13 more
wiley +1 more source
Advanced Science, EarlyView.The apple susceptibility‐related LRR‐RLK MdRLKT21 competitively binds to fungal sRNA effectors and subsequently activates defenses by salvaging the expression of MdRLKT1 and MdRLKT2 and thereby releasing the resistance protein MdRFP1. These findings provide new insights into the molecular mechanism by which plants counteract pathogen‐secreted sRNA ...
Mingliang Lei +7 more
wiley +1 more source
LARGE SCALE SYNTHESIS AND PURIFICATION OF FLAVIN ADENINE DINUCLEOTIDE
, 1956 Chester DeLuca, Nathan O. Kaplan
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Irradiated adenine sulphate as a source of vitamin B1 for growth [PDF]
, 1933 Barnett Sure
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Advanced Science, EarlyView.Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang +9 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals that Lead reprograms glucose metabolism to enhance H3K18la, driving DRP1‐dependent mitochondrial DNA leakage and cGAS‐STING‐mediated pyroptosis. Melatonin targets G6PD to suppress glycolysis‐driven H3K18la and restore mitochondrial homeostasis, thereby alleviating Lead‐induced liver injury in common carp through disruption of the ...
Zhiying Miao +4 more
wiley +1 more source
THE INCORPORATION OF THE PYRIMIDINE RING OF ADENINE INTO THE ISOALLOXAZINE RING OF RIBOFLAVIN
, 1956 Walter S. McNutt
openalex +1 more source