Results 151 to 160 of about 399,190 (328)
Advanced Science, EarlyView.It is reported that Fn14 inhibited EOC metastasis by regulating Slug‐mediated EMT. Furthermore, Fn14 altered the subcellular localization of SIRT2 by interacting with SIRT2, leading to reduced SIRT2 shuttling into the nucleus and subsequently promoting the acetylated degradation of Slug.
Anyue Wu +9 more
wiley +1 more source
THE DIRECT CONTRIBUTION OF ADENINE TO THE BIOGENESIS OF RIBOFLAVIN BY EREMOTHECIUM ASHBYII
, 1954 Walter S. McNutt
openalex +1 more source
Hydrogen‐Producing Catalysts Based on Ferredoxin Scaffolds
Advanced Science, EarlyView.Selected plant‐type ferredoxins that lack their natural [2Fe‐2S] clusters functionally bind a hydrogenase active site cofactor and act as hydrogenases themselves. In combination with photosystem I, the light‐dependent H₂ evolution almost matches the H₂ production rates of the natural system.
Yiting She +6 more
wiley +1 more source
Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy
Advanced Science, EarlyView.This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao +8 more
wiley +1 more source
THE INCORPORATION OF THE PYRIMIDINE RING OF ADENINE INTO THE ISOALLOXAZINE RING OF RIBOFLAVIN
, 1956 Walter S. McNutt
openalex +1 more source
Brief Report: On a Regulatory System of the Adenine Level in the Plasma Connected with Red Cell Maturation and its Effect on the Adenine Nucleotides of the Circulating Erythrocyte. Lack of Relation Between ATP-Level and Life Span of the Erythrocyte [PDF]
, 1969 I Syllm-Rapoport +3 more
openalex +1 more source
Engineered Cas12j‐8 is a Versatile Platform for Multiplexed Genome Modulation in Mammalian Cells
Advanced Science, EarlyView.Engineered through structure‐guided protein engineering, enCas12j‐8 significantly enhances the editing efficiency of compact Cas12j‐8 while maintaining high specificity. It enables efficient multiplexed genome editing and base editing using a single crRNA array, demonstrating broad applicability and therapeutic potential in genome engineering ...
Ru Meng +14 more
wiley +1 more source
Advanced Science, EarlyView.This study introduces an in situ assembly of fluorogenic RNA approach for screening natural anti‐liver fibrosis compounds and dynamic visualization of endogenous COL1A1 mRNA in live cells. It offers a simple, cost‐effective approach of visualizing RNA dynamics and conducting drug screening in live cells, presenting a significant potential for the ...
Rui Bai +6 more
wiley +1 more source