Results 141 to 150 of about 276,635 (308)
Adenine specific DNA chemical sequencing reaction
Reaction of DNA with K^PdCLt at pH 2.0 followed by a piperidine workup produces specific cleavage at adenine (A) residues. Product analysis revealed the K^PdCU reaction involves selective depurination at adenine, affording an excision reaction analogous ...
Brent L. Iverson, Peter B. Dervan
core
2, 8-DIHYDROXY ADENINE UROLITHIASIS ASSOCIATED WITH INCOMPLETE ADENINE PHOSPHORIBOSYLTRANSFERASE DEFICIENCY [PDF]
adenine phosphoribosy1transferaseの部分欠損による2,8-dihydroxy adenine 結石の1例を報告した。家族のAPRT活性測定では全員正常で遺伝関係認められずspontaneous mutationの可能性が示唆された。A case of 2, 8-dihydroxy adenine stones with incomplete deficiency of adenine phosphoribosyl-transferase is reported ...
高橋, 陽一 +3 more
core
Unveiling the complex vibronic structure of the canonical adenine cation
International audienceAdenine, a DNA base, exists as several tautomers and isomers that are closely lying in energy and that may form a mixture upon vaporization of solid adenine.
Garcia, Gustavo +8 more
core +1 more source
This study presents a label‐free spectroscopic platform to evaluate membrane protein conformation on patient‐derived glioblastoma cell membrane‐coated magnetic nanovectors. This work demonstrates that preserving membrane protein integrity during nanoparticle fabrication enhances homotypic tumor targeting and reduces hard protein corona formation ...
Daniele De Pasquale +16 more
wiley +1 more source
Adenine is one of the four principle bases of nucleic acid, the essential molecule of life and evolution. Apparently, only one configuration of adenine exists in nature giving it unique chemical and biological properties.
Michaelian, K +9 more
core +1 more source
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang +12 more
wiley +1 more source
Natural products possess potent pharmacological activities and health benefits. However, drawbacks such as water insolubility, poor stability, and low bioavailability limit their practical applications.
Liang Chen +6 more
doaj +1 more source
Vertical Ionization Energies of Adenine and 9-Methyl Adenine
Vertical ionization energies of 9-H adenine and 9-methyl adenine have been calculated with the following, ab initio, electron propagator methods: the outer valence Green’s function (OVGF), partial third-order theory (P3), and the third-order algebraic ...
O. Dolgounitcheva (1494832) +2 more
core +1 more source
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu +16 more
wiley +1 more source
Background: Adenine is a naturally occurring purine essential for life, but its excess intake can cause metabolic disturbances leading to cardiovascular complications, renal stones, gout, fatigue, and anemia.
Waleed Khaled Y. Albahadly +4 more
doaj +1 more source

