PET imaging of mitochondrial complex-I in the adenine-induced tubulointerstitial nephropathy mouse model using [<sup>18</sup>F]BCPP-BF. [PDF]
Dahl K +16 more
europepmc +1 more source
This study establishes an efficient oleaginous heterotrophic microalga, Schizochytrium, through chassis optimization and metabolic engineering, significantly enhancing fatty acid titers and productivities. It also identifies a regulatory mechanism that coordinates biomass and lipid synthesis, providing a rational target for metabolic pathway rewiring ...
Fangzhong Wang +7 more
wiley +1 more source
Quantitative and spatially defined functionalization of nanostructures by overcoming the strong steric hindrance through bioinspired nucleobase interactions. [PDF]
Chen H +6 more
europepmc +1 more source
The pAblo·pCasso self-curing vector toolset for unconstrained cytidine and adenine base-editing in Gram-negative bacteria [PDF]
Ekaterina Kozaeva +3 more
openalex +1 more source
Recombination R-triplex: H-bonds contribution to stability as revealed with minor base substitutions for adenine [PDF]
Anna K. Shchyolkina +4 more
openalex +1 more source
SP1‐Mediated Glycolytic Reprogramming Promotes Tumorigenesis and Progression in Pancreatic Cancer
Laser capture microdissection‐based proteomics of pancreatic intraepithelial neoplasia (PanIN) identifies specificity protein 1 (SP1) as a key driver of tumorigenesis and progression in pancreatic cancer through glycolytic remodeling. SP1 enhances aerobic glycolysis by transcriptionally activating 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase ...
Hexing Hang +21 more
wiley +1 more source
Effects of analogues of adenine nucleotides on increases in intracellular calcium mediated by P2T‐purinoceptors on human blood platelets [PDF]
David A. Hall, S.M.O. Hourani
openalex +1 more source
The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice
Piezo1 upregulates in cartilage callus during bone repair, where its deletion impairs ossification and healing in mice, while activation enhances these processes. Sirt1 positively regulates Piezo1 expression and activity to promote osteogenesis and bone repair in mice.
Donghao Gan +16 more
wiley +1 more source

