Results 21 to 30 of about 399,190 (328)

RETRACTED: Adenine Combined with Cisplatin Promotes Anticancer Activity against Hepatocellular Cancer Cells through AMPK-Mediated p53/p21 and p38 MAPK Cascades

open access: yesPharmaceuticals, 2022
Cisplatin has been widely used in cancer treatments. Recent evidence indicates that adenine has potential anticancer activities against various types of cancers. However, the effects of the combination of adenine and cisplatin on hepatocellular carcinoma
Jhen-Yu Huang   +4 more
doaj   +1 more source

DGR mutagenic transposition occurs via hypermutagenic reverse transcription primed by nicked template RNA. [PDF]

open access: yes, 2017
Diversity-generating retroelements (DGRs) are molecular evolution machines that facilitate microbial adaptation to environmental changes. Hypervariation occurs via a mutagenic retrotransposition process from a template repeat (TR) to a variable repeat ...
Guo, Huatao   +6 more
core   +3 more sources

Search for interstellar adenine [PDF]

open access: yesAstrophysics and Space Science, 2015
13 pages, 6 figures, Accepted in Astrophys Space ...
Sonali Chakrabarti   +5 more
openaire   +3 more sources

Trypanosoma brucei methylthioadenosine phosphorylase protects the parasite from the antitrypanosomal effect of deoxyadenosine [PDF]

open access: yes, 2016
Trypanosoma brucei causes African sleeping sickness for which no vaccine exists and available treatments are of limited use due to their high toxicity or lack of efficacy. T.
de Koning, Harry P.   +4 more
core   +1 more source

Adenine deaminase and adenine utilization in Saccharomyces cerevisiae [PDF]

open access: yesJournal of Bacteriology, 1992
Compared with other purine salvage and nitrogen catabolism enzymatic activities, adenine deaminase (adenine aminohydrolase [AAH]; EC 3.5.4.2) activity in Saccharomyces cerevisiae is uniquely regulated. AAH specific activity is not induced by adenine and is reduced sevenfold when cells are cultivated in medium containing proline in place of ammonium as ...
openaire   +3 more sources

Immobilization and 3D Hot-Junction Formation of Gold Nanoparticles on Two-Dimensional Silicate Nanoplatelets as Substrates for High-Efficiency Surface-Enhanced Raman Scattering Detection

open access: yesNanomaterials, 2019
We synthesize a high-efficiency substrate for surface-enhanced Raman scattering (SERS) measurements, which is composed of gold nanoparticles (AuNPs) on two-dimensional silicate nanoplatelets acting as an inorganic stabilizer, via the in-situ reduction of
Yen-Chen Lee, Chih-Wei Chiu
doaj   +1 more source

Fluorescence kinetics of flavin adenine dinucleotide in different microenvironments [PDF]

open access: yes, 2013
Fluorescence kinetics of flavin adenine dinucleotide was measured in a wide time and spectral range in different media, affecting its intra- end extramolecular interactions, and analyzed by a new method based on compressed ...
A. Makai   +18 more
core   +2 more sources

HOTSPOT STABILIZATION OF GOLD NANOPARTICLES FOR APPLICATION OF QUANTITATIVE SERS IN BIOANALYTICAL SYSTEMS [PDF]

open access: yesQuímica Nova
A complete procedure including synthesizing gold nanoparticles and further hotspots stabilization is presented. Colloidal gold synthesis followed a citrate reducing reaction, then, an ideal condition for SERS enhancement with quantitative purposes was ...
Mónica B. Mamián-López   +1 more
doaj   +2 more sources

Dissociative multi-photon ionization of isolated uracil and uracil-adenine complexes [PDF]

open access: yes, 2016
Recent multi-photon ionization (MPI) experiments on uracil revealed a fragment ion at m/z 84 that was proposed as a potential marker for ring opening in the electronically excited neutral molecule.
Barc, B.   +7 more
core   +2 more sources

Crystallographic and SAXS studies of S-adenosyl-l-homocysteine hydrolase from Bradyrhizobium elkanii

open access: yesIUCrJ, 2017
S-Adenosyl-l-homocysteine hydrolase (SAHase) from the symbiotic bacterium Bradyrhizobium elkanii (BeSAHase) was crystallized in four ligand complexes with (i) mixed adenosine (Ado) and cordycepin (Cord; 3′-deoxyadenosine), (ii) adenine (Ade), (iii) Ado ...
Tomasz Manszewski   +2 more
doaj   +1 more source

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