Cisplatin has been widely used in cancer treatments. Recent evidence indicates that adenine has potential anticancer activities against various types of cancers. However, the effects of the combination of adenine and cisplatin on hepatocellular carcinoma
Jhen-Yu Huang+4 more
doaj +1 more source
DGR mutagenic transposition occurs via hypermutagenic reverse transcription primed by nicked template RNA. [PDF]
Diversity-generating retroelements (DGRs) are molecular evolution machines that facilitate microbial adaptation to environmental changes. Hypervariation occurs via a mutagenic retrotransposition process from a template repeat (TR) to a variable repeat ...
Guo, Huatao+6 more
core +3 more sources
Search for interstellar adenine [PDF]
13 pages, 6 figures, Accepted in Astrophys Space ...
Sonali Chakrabarti+5 more
openaire +3 more sources
Trypanosoma brucei methylthioadenosine phosphorylase protects the parasite from the antitrypanosomal effect of deoxyadenosine [PDF]
Trypanosoma brucei causes African sleeping sickness for which no vaccine exists and available treatments are of limited use due to their high toxicity or lack of efficacy. T.
de Koning, Harry P.+4 more
core +1 more source
Adenine deaminase and adenine utilization in Saccharomyces cerevisiae [PDF]
Compared with other purine salvage and nitrogen catabolism enzymatic activities, adenine deaminase (adenine aminohydrolase [AAH]; EC 3.5.4.2) activity in Saccharomyces cerevisiae is uniquely regulated. AAH specific activity is not induced by adenine and is reduced sevenfold when cells are cultivated in medium containing proline in place of ammonium as ...
openaire +3 more sources
We synthesize a high-efficiency substrate for surface-enhanced Raman scattering (SERS) measurements, which is composed of gold nanoparticles (AuNPs) on two-dimensional silicate nanoplatelets acting as an inorganic stabilizer, via the in-situ reduction of
Yen-Chen Lee, Chih-Wei Chiu
doaj +1 more source
Fluorescence kinetics of flavin adenine dinucleotide in different microenvironments [PDF]
Fluorescence kinetics of flavin adenine dinucleotide was measured in a wide time and spectral range in different media, affecting its intra- end extramolecular interactions, and analyzed by a new method based on compressed ...
A. Makai+18 more
core +2 more sources
HOTSPOT STABILIZATION OF GOLD NANOPARTICLES FOR APPLICATION OF QUANTITATIVE SERS IN BIOANALYTICAL SYSTEMS [PDF]
A complete procedure including synthesizing gold nanoparticles and further hotspots stabilization is presented. Colloidal gold synthesis followed a citrate reducing reaction, then, an ideal condition for SERS enhancement with quantitative purposes was ...
Mónica B. Mamián-López+1 more
doaj +2 more sources
Dissociative multi-photon ionization of isolated uracil and uracil-adenine complexes [PDF]
Recent multi-photon ionization (MPI) experiments on uracil revealed a fragment ion at m/z 84 that was proposed as a potential marker for ring opening in the electronically excited neutral molecule.
Barc, B.+7 more
core +2 more sources
Crystallographic and SAXS studies of S-adenosyl-l-homocysteine hydrolase from Bradyrhizobium elkanii
S-Adenosyl-l-homocysteine hydrolase (SAHase) from the symbiotic bacterium Bradyrhizobium elkanii (BeSAHase) was crystallized in four ligand complexes with (i) mixed adenosine (Ado) and cordycepin (Cord; 3′-deoxyadenosine), (ii) adenine (Ade), (iii) Ado ...
Tomasz Manszewski+2 more
doaj +1 more source