Results 221 to 230 of about 19,445 (257)

Expanding the genetic toolkit: adenine and cytosine base editors for gene disruption in Aspergillus niger. [PDF]

Microb Cell Fact
Yuan G, Deng S, Dai Z, Hofstad BA, Pomraning KR.   +4 more
europepmc   +1 more source

Transcriptional Regulation of the Novel Theacrine Synthase Gene CsTcS2 by the CsTINY–CsWRKY33 Module Underpins Theacrine Biosynthesis in Camellia sinensis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Theacrine (1,3,7,9‐tetramethyluric acid) is a purine alkaloid detected in multiple wild and specialised tea germplasms (Camellia sinensis) from South China, including Kucha. However, the molecular mechanisms governing its biosynthesis remain poorly understood. Here, we identify CsTcS2 as a novel theacrine synthase in tea plant.
Ting Wu, Lihua Zhu, Chenyu Shao, Siyi Xie, Na Li, Xinyu Li, Fang Wang, Lvwen Peng, Huiying Jin, Fanghuizi Shang, Jianan Huang, Zhonghua Liu, Na Tian, Shuoqian Liu   +13 more
wiley   +1 more source

ABE9 fused to SpRY Cas9 nickase enables precise generation of bystander free mouse models. [PDF]

Sci Rep
Ong JK, Bhunia S, Hilbert B, Kirschner V, Duglosz S, Zimmermann F, Freichel M, Cornean A.   +7 more
europepmc   +1 more source

OsMYB306‐OsRAV11 Regulates Resistance of Rice to Striped Stem Borer by Modulating Serotonin Biosynthesis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Striped stem borer (SSB; Chilo suppressalis Walker) is one of the most destructive pests in rice production. Previous studies have demonstrated that SSB infestation induces transcription of OsT5H (tryptamine‐5‐hydroxylase) and biosynthesis of serotonin, a newly recognised phytohormone, and that disruption of serotonin biosynthesis ...
Jia‐Run Zhang, Long Wang, Yang‐Fan Chen, Xiao‐Hao Guo, Meng Jiang, Yuan‐Yuan Tan, Qing Wang, Qiu Qian, Angharad M. R. Gatehouse, Qing‐Yao Shu   +9 more
wiley   +1 more source

sgRNA amount is a limiting factor in adenine base editing using RNA LNPs. [PDF]

Mol Ther Nucleic Acids
Birkenshaw A, Thomson T, Truong MP, Komaki Y, Ramsden N, Timpano A, Huang C, Blakney AK, Kurek DZ, Kulkarni J, Ross CJD.   +10 more
europepmc   +1 more source

Editing and synthetic engineering of chloroplast genomes. [PDF]

Plant Commun
Fu J, Zhang J.
europepmc   +1 more source

On the Calculations of Electron Impact Ionization Cross-Sections for Selected Nucleosides and Deoxyribose Molecules. [PDF]

Molecules
Możejko P.
europepmc   +1 more source

<i>In vivo</i> adenine base editing rescues brain biochemistry and improves motor deficits in a common phenylketonuria variant. [PDF]

Mol Ther Adv
Gautier MK, King K, Han Y, Said H, Alameh MG, Wang X, Hong X, Musunuru K, Ahrens-Nicklas RC.   +8 more
europepmc   +1 more source

Base editing rescues seizures and sudden death in a SCN8A mutation-associated developmental epileptic encephalopathy model. [PDF]

J Clin Invest
Reever CM, Boscia AR, Deutsch TC, Patel MP, Miralles RM, Kittur S, Fleischel EJ, Buo AM, Yorek MS, Meisler MH, Farber CR, Patel MK.   +11 more
europepmc   +1 more source

Engineering Herbicide Cross‐Resistance in Rapeseed by Generating Stacked BnaALS Mutations via Sequential CBE and ABE8e‐SpRY Editing

Plant Biotechnology Journal, EarlyView.
Sichao Ren, Wenjing Lei, Jiaqi He, Meng Jia, Yu Liu, Jialin Fan, Yumei Wang, Li Lin, Hui Zhang, Youping Wang, Jian Wu   +10 more
wiley   +1 more source