Results 151 to 160 of about 353,387 (184)
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Comparison of the adenine nucleotide translocase in hepatomas and rat liver mitochondria
Biochimica Et Biophysica Acta - Biomembranes, 1979Various biochemical properties of the adenine nucleotide translocase were compared with mitochondria prepared from control and host liver, and Morris hepatomas 7777, 7800 and 5123C. The transport of phosphoenolpyruvate on the adenine nucleotide translocase was found to be three to four times more active, and inhibition of the transporter by palmitoyl ...
Earl Shrago, Stanley Goldfarb
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Increase in the adenine nucleotide translocase content of duckling subsarcolemmal mitochondria during cold acclimation [PDF]
FEBS Letters, 2000 Intermyofibrillar and subsarcolemmal mitochondria were isolated from duckling gastrocnemius muscle. The adenine nucleotide translocase (ANT) content of subsarcolemmal mitochondria was found to be half of that present in intermyofibrillar mitochondria. In
Damien Roussel +2 more
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Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells [PDF]
FEBS Letters, 2004 Mitochondrial adenine nucleotide translocase 1 (ANT1), but not ANT2, can dominantly induce apoptosis [Bauer et al. (1999) J. Cell Biol. 439, 258–262]. Nothing is known, however, about the apoptotic activity of ANT3.
Meritxell Granell
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The evolution of the adenine nucleotide translocase family
Gene, 2004Homologous genes are grouped into families whose evolution may be different in the various organisms. For the variety of the processes and the well-known mechanism of gene gain and gene loss, which takes place in genome evolution, we deal in comparative analyses with a "one-to-many" or a "many-to-many" relationship between homologous genes going from ...
Santamaria M, Lanave C, Saccone C
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Adenine Nucleotide Translocase in the Focus of Cardiovascular Diseases
Trends in Cardiovascular Medicine, 2007Adenine nucleotide translocase (ANT) facilitates the exchange of extramitochondrial adenosine diphosphate and intramitochondrial adenosine triphosphate across the inner mitochondrial membrane and appears to be a member of the mitochondrial permeability transition pore whose opening induces apoptosis.
Andrea, Dörner +1 more
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Chemosensitization by Knockdown of Adenine Nucleotide Translocase-2
Cancer Research, 2006Abstract Mitochondrial membrane permeabilization (MMP) is a rate-limiting step of apoptosis, including in anticancer chemotherapy. Adenine nucleotide translocase (ANT) mediates the exchange of ADP and ATP on the inner mitochondrial membrane in healthy cells.
Le Bras, M. +11 more
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Biochimica Et Biophysica Acta - Bioenergetics, 1982
The adenine nucleotide content (ATP+ADP+AMP) of newborn rabbit liver mitochondria was 6.0 +/- 0.5 nmol/mg mitochondrial protein at birth, increased rapidly to 14.5 +/- 1.7 nmol/mg protein by 2 h postnatal, peaked at 6 h, then decreased gradually to 7.8 +/- 0.6 nmol/mg protein by 4 days postnatal.
June R Aprille, J R Aprille
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The adenine nucleotide content (ATP+ADP+AMP) of newborn rabbit liver mitochondria was 6.0 +/- 0.5 nmol/mg mitochondrial protein at birth, increased rapidly to 14.5 +/- 1.7 nmol/mg protein by 2 h postnatal, peaked at 6 h, then decreased gradually to 7.8 +/- 0.6 nmol/mg protein by 4 days postnatal.
June R Aprille, J R Aprille
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An adenine nucleotide translocase in the procaryote Methanobacterium thermoautotrophicum
Biochemical and Biophysical Research Communications, 1980Abstract ATP synthesis, ATP hydrolysis and ADP uptake by membrane vesicles of Methanobacterium thermoautotrophicum are inhibited by inhibitors of mitochondrial ADP ATP translocases. Atractyloside binds to one of the membrane proteins. These data demonstrate the presence of an eucaryotic type of ADP ATP translocase in a procaryotic ...
H J, Doddema +4 more
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Adenine nucleotide translocase 2 is a key mitochondrial protein in cancer metabolism
Biochimica Et Biophysica Acta - Bioenergetics, 2011 Adenine nucleotide translocase (ANT), a mitochondrial protein that facilitates the exchange of ADP and ATP across the mitochondrial inner membrane, plays an essential role in cellular energy metabolism. Human ANT presents four isoforms (ANT1-4), each with a specific expression depending on the nature of the tissue, cell type, developmental stage and ...
Arnaud Chevrollier +2 more
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The Adenine Nucleotide Translocase 2, a Mitochondrial Target for Anticancer Biotherapy
Current Drug Targets, 2011Apoptosis or programmed cell death is one of the most important signaling pathways, which controls the cell fate and is frequently impaired in cancer cells. The major consequences of apoptosis inhibition are the accumulation of mutated cells and their enhanced resistance to chemotherapeutic agents.
Ossama, Sharaf el dein +3 more
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