Results 1 to 10 of about 1,015 (68)
Astaxanthin Inhibits Mitochondrial Permeability Transition Pore Opening in Rat Heart Mitochondria
Antioxidants, 2019 The mitochondrion is the main organelle of oxidative stress in cells. Increased permeability of the inner mitochondrial membrane is a key phenomenon in cell death. Changes in membrane permeability result from the opening of the mitochondrial permeability
Yulia Baburina +5 more
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Neural Regeneration Research, 2023 The mitochondrial permeability transition pore is a nonspecific transmembrane channel. Inhibition of mitochondrial permeability transition pore opening has been shown to alleviate mitochondrial swelling, calcium overload, and axonal degeneration ...
Yang Yang +12 more
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Antamanide, a derivative of Amanita phalloides, is a novel inhibitor of the mitochondrial permeability transition pore. [PDF]
PLoS ONE, 2011 Antamanide is a cyclic decapeptide derived from the fungus Amanita phalloides. Here we show that antamanide inhibits the mitochondrial permeability transition pore, a central effector of cell death induction, by targeting the pore regulator cyclophilin D.
Luca Azzolin +8 more
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Frontiers in Cell and Developmental Biology, 2023 Acute lymphoblastic leukemia (aLL) is a malignant cancer in the blood and bone marrow characterized by rapid expansion of lymphoblasts. It is a common pediatric cancer and the principal basis of cancer death in children.
Jung Kwon Lee +2 more
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An X-ray micro-tomographic study of the pore space, permeability and percolation threshold of young sea ice [PDF]
The Cryosphere, 2021 The hydraulic permeability of sea ice is an important property that influences the role of sea ice in the environment in many ways. As it is difficult to measure, so far not many observations exist, and the quality of deduced empirical relationships ...
S. Maus, M. Schneebeli, A. Wiegmann
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background The opening of mitochondrial permeability transition pore and inflammation cooperatively progress myocardial ischemia‐reperfusion (IR) injury, which hampers therapeutic effects of primary reperfusion therapy for acute myocardial infarction. We
Gentaro Ikeda +7 more
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Biochemistry Research International, 2020 Mitochondrial permeability transition is characterized by the opening of a transmembranal pore that switches membrane permeability from specific to nonspecific.
Edmundo Chávez +5 more
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The use of the Petri net method in the simulation modeling of mitochondrial swelling [PDF]
The Ukrainian Biochemical Journal, 2016 Using photon correlation spectroscopy, which allows investigating changes in the hydrodynamic diameter of the particles in suspension, it was shown that ultrahigh concentrations of Ca2+ (over 10 mM) induce swelling of isolated mitochondria.
Yu. V. Danylovych +3 more
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The Role of Adenine Nucleotide Translocase in the Mitochondrial Permeability Transition
Cells, 2020 The mitochondrial permeability transition, a Ca2+-induced significant increase in permeability of the inner mitochondrial membrane, plays an important role in various pathologies.
Nickolay Brustovetsky
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Journal of Glaciology, 2022 Sea-ice pore microstructure constrains ice transport properties, affecting fluid flow relevant to oil-in-ice transport and biogeochemical processes. Motivated by a lack of pore microstructural data, in particular for granular ice and across the seasonal ...
Marc Oggier, Hajo Eicken
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