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The objective of this study was to investigate the applicability of liquid chromatography coupled with high resolution product scan (LC/HRPS) mass spectrometry for simultaneous quantification of adenine nucleotides, creatine phosphate, and creatine ...
Pavlo Fedorov+5 more
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Conformationally Restricted Adenine Nucleotide Analogs in Mitochondrial Adenine Nucleotide Transport
Abstract The conformationally restricted adenine nucleotide analogs 8,3′anhydro-8-oxy-9-(β-ᴅ-xylofurano-syl) adenine-5′-O-tri (di) -phosphate (I) , and 8,2′-anhydro-8-oxy-9-(β-ᴅ-arabinofuranosyl) adenine-5′-O-tri (di)-phosphate (II), were prepared chemically as their α-32P-labelled compounds and compared with syn-structured 8-bromo AT(D)
Morio Ikehara+2 more
openaire +3 more sources
Towards RNA life on Early Earth: From atmospheric HCN to biomolecule production in warm little ponds [PDF]
The origin of life on Earth involves the early appearance of an information-containing molecule such as RNA. The basic building blocks of RNA could have been delivered by carbon-rich meteorites, or produced in situ by processes beginning with the synthesis of hydrogen cyanide (HCN) in the early Earth's atmosphere.
arxiv +1 more source
Water dimer driven DNA base superstructure with mismatched hydrogen-bonding [PDF]
The existence of water dimers in equilibrium water vapor at room temperature and their anomalous properties revealed by recent studies suggest the benchmark role of water dimer in both experiment and theory. However, there has been a limited observation of individual water dimers due to the challenge of water separation and generation at the single ...
arxiv +1 more source
The giant mottled eel is a species with high commercial value so overfishing, river management, and water pollution have negatively affected its movement and population numbers. Anguilla marmorata (eel) was listed in the Vietnam Red Data Book 2007 with a
Kieu Thi Huyen, Nguyen Quang Linh
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Vibrational Investigation of Nucleobases by Means of Divide and Conquer Semiclassical Dynamics [PDF]
In this work we report a computational study of the vibrational features of four different nucleobases employing the divide-and-conquer semiclassical initial value representation molecular dynamics method. Calculations are performed on uracil, cytosine, thymine, and adenine.
arxiv +1 more source
Evaluation of functioning of mitochondrial electron transport chain with NADH and FAD autofluorescence [PDF]
We prove the feasibility of evaluation of mitochondrial electron transport chain function in isolated mitochondria of smooth muscle cells of rats from uterus using fluorescence of NADH and FAD coenzymes. We found the inversely directed changes in FAD and
H. V. Danylovych
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Distributions of Bubble Lifetimes and Bubble Lengths in DNA [PDF]
We investigate the distribution of bubble lifetimes and bubble lengths in DNA at physiological temperature, by performing extensive molecular dynamics simulations with the Peyrard-Bishop-Dauxois (PBD) model, as well as an extended version (ePBD) having a sequence-dependent stacking interaction, emphasizing the effect of the sequences' guanine-cytosine (
arxiv +1 more source
Control of ATP homeostasis during the respiro‐fermentative transition in yeast
Respiring Saccharomyces cerevisiae cells respond to a sudden increase in glucose concentration by a pronounced drop of their adenine nucleotide content ([ATP]+[ADP]+[AMP]=[AXP]).
Thomas Walther+6 more
doaj +1 more source
It recently has been established that adenine-containing cofactors, including nicotinamide adenine dinucleotide (NAD+), reduced nicotinamide adenine dinucleotide (NADH), and 3’-desphospho-coenzyme A (dpCoA), can serve as ‘non-canonical initiating ...
Jeremy Bird+2 more
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