Results 241 to 250 of about 116,785 (352)

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing N6‐Methyladenosine Methylation of Myc

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu   +5 more
wiley   +1 more source

Development and implementation of an LC-MS-based multi-attribute method for adeno-associated virus. [PDF]

open access: yesMol Ther Methods Clin Dev
Powers TW   +5 more
europepmc   +1 more source

PRMT5 Mediates Sepsis‐Associated Lung Injury by Modulating JAK1 Arginine Methylation: A Mechanism Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley   +1 more source

Transcription factor EB activation rescues advanced αB-crystallin mutation-induced cardiomyopathy by normalizing desmin localization [PDF]

open access: yes, 2019
Benjamin, Ivor J   +12 more
core   +1 more source

Managing the meniscus Part 2: Traumatic tear patterns, biologic augmentation, transplantation, innovation and future research

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Acute, traumatic meniscus tears are common and should be repaired whenever possible. However, the biological age of the patient, along with the specific tear morphology, may significantly influence the selection of the repair technique, expected clinical outcomes and the postoperative rehabilitation protocol.
Armin Runer   +15 more
wiley   +1 more source

Chinese guidance for the clinical application of adeno-associated virus vector-based gene therapy for hemophilia B (2025). [PDF]

open access: yesBlood Sci
Xue F   +25 more
europepmc   +1 more source

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