Results 281 to 290 of about 396,665 (375)

Direct Identification and Quantification of Recombinant Adeno-Associated Virus in Crude Cell Lysate and Conditioned Medium by Mass Photometry. [PDF]

Anal Chem
Yamaguchi Y, Shimojo S, Shibuya R, Bandoh K, Matsushita A, Fukuhara M, Tsunaka Y, Torisu T, Uchiyama S.   +8 more
europepmc   +1 more source

Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector.

, 1996
Xiao Xiao, Juan Li, R. Jude Samulski
openalex   +2 more sources

High-Titer, Wild-Type Free Recombinant Adeno-Associated Virus Vector Production Using Intron-Containing Helper Plasmids [PDF]

, 2000
Lei Cao, Yuhong Liu, Matthew J. During, Weidong Xiao   +3 more
openalex   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Adeno-associated virus vector modification based on directed evolution technology for gene therapy targeting head and neck squamous cell carcinoma. [PDF]

Front Oncol
Zhu Y, Ji W, Zhang Q, Dong Y, Liu L.
europepmc   +1 more source

Saikosaponin b1 Attenuates Liver Fibrosis by Blocking STAT3/Gli1 Interaction and Inducing Gli1 Degradation

Exploration, EarlyView.
Saikosaponin b1 attenuates liver fibrosis by competitively disrupting the interaction between signal transducer and activator of transcription 3 (STAT3) and glioma‐associated oncogene‐1 (Gli1) in the activated hepatic stellate cells (HSCs). The blocked interaction of STAT3 and Gli1 promotes the degradation of Gli1, inhibits Gli1 transcriptional ...
Meiyu Shao, Xiaoqing Zhang, Jiamei Sun, Hongyan Dong, Xin Han, Qiao Yang, Roufen Chen, Liteng Shen, Lei Xu, Lu Wang, Bo Zhu, Dongxin Tang, Shuosheng Zhang, Keda Lu, Mengyun Peng, Gang Cao   +15 more
wiley   +1 more source

Erratum: Assessment of adeno-associated virus purity by capillary electrophoresis-based western. [PDF]

Mol Ther Methods Clin Dev
Acevedo J, Bi Y, Gee J, Khatwani SL.
europepmc   +1 more source

Gene Therapy Vectors Based on Adeno-Associated Virus Type 1

, 1999
Weidong Xiao, Narendra Chirmule, Scott C. Berta, Beth McCullough, Guangping Gao, James M. Wilson   +5 more
openalex   +1 more source

Nanoplatform‐Enabled Genetic Interventions for Central Nervous System Disorders: Advances in Delivery Strategies and Therapeutic Potential

Advanced Genetics, EarlyView.
This review provides a detailed description of gene mutations and epigenetic mechanisms in central nervous system (CNS) disease, strategies for gene therapy, challenges for CNS gene therapy and gene‐drug nanocarriers. This review also summarizes the applications of nanogenetic therapy platforms in CNS diseases (brain tumors, neurodegenerative diseases,
Fuming Liang, Shizhen Cui, Jing Yang, Zhaohui He, Ling Zhu   +4 more
wiley   +1 more source

Harnessing cell aggregates for enhanced adeno-associated virus manufacturing: Cultivation strategies and scale-up considerations. [PDF]

Biotechnol Prog
Ladd B, Gräslund T, Chotteau V.
europepmc   +1 more source