Results 21 to 30 of about 612,957 (295)

Exploring the Relationship between E-Cadherin and β-Catenin Cell Adhesion Proteins and Periacinar Retraction Clefting in Prostatic Adenocarcinoma

open access: yesDiagnostics
Background: Periacinar retraction clefts represent a histopathological criterion supporting the diagnosis of prostatic adenocarcinoma. The origin of these clefts in prostatic adenocarcinoma remains unclear.
Rinë Limani   +2 more
doaj   +1 more source

PD-L1 expression in squamous-cell carcinoma and adenocarcinoma of the lung

open access: yesRadiology and Oncology, 2017
With introduction of immunotherapy (IT) into the treatment of advanced non-small-cell lung cancer (NSCLC), a need for predictive biomarker became apparent. Programmed death ligand 1 (PD-L1) protein expression is most widely explored predictive marker for
Janzic Urska   +4 more
doaj   +1 more source

The high-density lipoprotein binding protein HDLBP is an unusual RNA-binding protein with multiple roles in cancer and disease

open access: yesRNA Biology
The high-density lipoprotein binding protein (HDLBP) is the human member of an evolutionarily conserved family of RNA-binding proteins, the vigilin protein family.
Jonathan Feicht, Ralf-Peter Jansen
doaj   +1 more source

Primary mucinous adenocarcinoma at the end ileostomy site with multiple metachronous colorectal cancers: A case report

open access: yesWorld Journal of Colorectal Surgery, 2022
Adenocarcinoma occurring at the end ileostomy site is a rare complication, with 70 cases reported in the literature to date. Most patients with adenocarcinoma occurring at the ileostomy site underwent total proctocolectomy for ulcerative colitis and ...
Himanshu Shekhar   +4 more
doaj   +1 more source

Adenocarcinoma of the pancreas [PDF]

open access: yesSeminars in Diagnostic Pathology, 2014
Infiltrating ductal adenocarcinoma of the pancreas is a real enigma. On one hand, it is one of the most deadly of all of the solid malignancies. On the other hand, the neoplastic glands can be remarkably well-differentiated, and it can be difficult to distinguish between a reactive non-neoplastic gland and a gland of invasive adenocarcinoma.
Ralph H. Hruban, David S. Klimstra
openaire   +3 more sources

Adenocarcinoma of the esophagus [PDF]

open access: yesCancer, 1979
The relevant literature is reviewed in an attempt to clarify the true frequency of intraesophageal adenocarcinoma and to evaluate the different treatment modalities and survival of this uncommon type of tumor. The incidence of intraesophageal adenocarcinoma in reported clinical series is about 1%, and data from cancer registries show the incidence to ...
William L. Caldwell   +2 more
openaire   +3 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

Case of adenohypophysis adenocarcinoma according to postmortem results

open access: yesPatologìâ, 2012
This article describes a case of rare disease – adenocarcinoma of adenohypophysis. A tumour had extremely small size and was accompanied by destruction of wall of the sella turcica and invasion of blood vessels, that resulted in development of thrombosis
N. Yu. Ozerova
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

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