Results 21 to 30 of about 426,766 (100)

Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma

Nature Genetics, 2020
Brain metastases from lung adenocarcinoma (BM-LUAD) frequently cause patient mortality. To identify genomic alterations that promote brain metastases, we performed whole-exome sequencing of 73 BM-LUAD cases.
D. Shih, D. Shih, Naema Nayyar, Ivanna V. Bihun, Ivanna V. Bihun, I. Dagogo-Jack, C. Gill, C. Gill, Elisa Aquilanti, Elisa Aquilanti, Mia S Bertalan, Alexander Kaplan, M. D’Andrea, U. Chukwueke, F. M. Ippen, C. Alvarez-Breckenridge, Nicholas D. Camarda, Matthew Lastrapes, Devin McCabe, Devin McCabe, Benjamin M Kuter, B. Kaufman, B. Kaufman, M. Strickland, J. Martinez‐Gutierrez, J. Martinez‐Gutierrez, Deepika Nagabhushan, Magali De Sauvage, Michael D. White, Brandyn Castro, Kaitlin Hoang, Andrew Kaneb, Emily Batchelor, S. Paek, S. H. Park, M. Martinez-Lage, A. Berghoff, Parker Merrill, E. Gerstner, T. Batchelor, M. Frosch, Ryan P. Frazier, D. Borger, A. Iafrate, B. Johnson, S. Santagata, S. Santagata, M. Preusser, D. Cahill, S. Carter, P. Brastianos, P. Brastianos   +51 more
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Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

Proceedings of the National Academy of Sciences of the United States of America, 2001
We have generated a molecular taxonomy of lung carcinoma, the leading cause of cancer death in the United States and worldwide. Using oligonucleotide microarrays, we analyzed mRNA expression levels corresponding to 12,600 transcript sequences in 186 lung
Arindam Bhattacharjee, William G. Richards, Jane Staunton, Cheng Li, Stefano Monti, Priya Vasa, C. Ladd, J. Beheshti, Raphael Bueno, Michael A Gillette, Massimo Loda, G. Weber, Eugene J. Mark, Eric S. Lander, W. Wong, Bruce E. Johnson, Todd R. Golub, D. Sugarbaker, M. Meyerson   +18 more
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Pancreatic Adenocarcinoma, Version 1.2019.

The Journal of the National Comprehensive Cancer Network, 2019
The NCCN Guidelines for Pancreatic Adenocarcinoma discuss the diagnosis and management of adenocarcinomas of the exocrine pancreas and are intended to assist with clinical decision-making.
Margaret Tempero, M. Malafa, E. G. Chiorean, B. Czito, C. Scaife, A. Narang, Christos Fountzilas, B. Wolpin, M. Al-Hawary, H. Asbun, Stephen W. Behrman, Al B. Benson, Ellen F. Binder, D. Cardin, Charles Cha, V. Chung, M. Dillhoff, E. Dotan, C. Ferrone, G. Fisher, J. Hardacre, William Hawkins, Andrew H. Ko, N. Loconte, Andrew M. Lowy, C. Moravek, E. Nakakura, Eileen M. O’Reilly, Jorge V. Obando, S. Reddy, S. Thayer, Robert A. Wolff, Jennifer L. Burns, Griselda Zuccarino-Catania   +33 more
semanticscholar   +1 more source

Cell death-based treatment of lung adenocarcinoma

Cell Death and Disease, 2018
The most common type of lung cancer is adenocarcinoma (ADC), comprising around 40% of all lung cancer cases. In spite of achievements in understanding the pathogenesis of this disease and the development of new approaches in its treatment, unfortunately,
T. Denisenko, I. Budkevich, B. Zhivotovsky   +2 more
semanticscholar   +1 more source

Pancreatic Adenocarcinoma, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.

The Journal of the National Comprehensive Cancer Network, 2017
Ductal adenocarcinoma and its variants account for most pancreatic malignancies. High-quality multiphase imaging can help to preoperatively distinguish between patients eligible for resection with curative intent and those with unresectable disease ...
M. Tempero, M. Malafa, M. Al-Hawary, H. Asbun, Andrew J. Bain, S. Behrman, A. Benson, E. Binder, D. Cardin, Charles Cha, E. Chiorean, V. Chung, B. Czito, Mary E. Dillhoff, E. Dotan, C. Ferrone, J. Hardacre, W. Hawkins, J. Herman, A. Ko, S. Komanduri, A. Koong, N. Loconte, A. Lowy, C. Moravek, E. Nakakura, E. O’Reilly, Jorge V. Obando, S. Reddy, C. Scaife, S. Thayer, C. Weekes, R. Wolff, B. Wolpin, J. Burns, S. Darlow   +35 more
semanticscholar   +1 more source

Predicting EGFR mutation status in lung adenocarcinoma on computed tomography image using deep learning

European Respiratory Journal, 2019
Epidermal growth factor receptor (EGFR) genotyping is critical for treatment guidelines such as the use of tyrosine kinase inhibitors in lung adenocarcinoma.
Shuo Wang, Jingyun Shi, Z. Ye, D. Dong, Dongdong Yu, Mu Zhou, Y. Liu, O. Gevaert, Kun Wang, Yongbei Zhu, Hongyu Zhou, Zhenyu Liu, Jie Tian   +12 more
semanticscholar   +1 more source

Pancreatic Ductal Adenocarcinoma: Current and Evolving Therapies

International Journal of Molecular Sciences, 2017
Pancreatic ductal adenocarcinoma (PDAC), which constitutes 90% of pancreatic cancers, is the fourth leading cause of cancer-related deaths in the world.
A. Adamska, A. Domenichini, M. Falasca
semanticscholar   +1 more source

Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction.

New England Journal of Medicine, 2001
BACKGROUND Surgical resection of adenocarcinoma of the stomach is curative in less than 40 percent of cases. We investigated the effect of surgery plus postoperative (adjuvant) chemoradiotherapy on the survival of patients with resectable adenocarcinoma ...
J. Macdonald, S. Smalley, J. Benedetti, S. Hundahl, N. Estes, G. Stemmermann, D. Haller, J. Ajani, L. Gunderson, J. Jessup, J. Martenson   +10 more
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International Endocervical Adenocarcinoma Criteria and Classification (IECC): A New Pathogenetic Classification for Invasive Adenocarcinomas of the Endocervix

American Journal of Surgical Pathology, 2018
We sought to classify endocervical adenocarcinomas (ECAs) based on morphologic features linked to etiology (ie, human papillomavirus [HPV] infection), unlike the World Health Organization 2014 classification. The International Endocervical Adenocarcinoma
S. Stolnicu, Iulia Bârsan, L. Hoang, Prusha Patel, C. Terinte, A. Pesci, S. Aviel‐Ronen, T. Kiyokawa, I. Alvarado-Cabrero, M. Pike, E. Oliva, Kay J. Park, R. Soslow   +12 more
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Mucinous colorectal adenocarcinoma: clinical pathology and treatment options

Cancer Communications, 2019
Mucinous colorectal adenocarcinoma is a distinct subtype of colorectal cancer (CRC) characterized by the presence of abundant extracellular mucin which accounts for at least 50% of the tumor volume.
C. Luo, S. Cen, Guojun Ding, Wei Wu
semanticscholar   +1 more source