Results 31 to 40 of about 426,766 (100)
A Prospective, Molecular Epidemiology Study of EGFR Mutations in Asian Patients with Advanced Non–Small-Cell Lung Cancer of Adenocarcinoma Histology (PIONEER)
Journal of Thoracic Oncology, 2014 Introduction: PIONEER (NCT01185314) was a prospective, multinational, epidemiological study of epidermal growth factor receptor (EGFR) mutations in patients from Asia with newly diagnosed advanced lung adenocarcinoma. Methods: Eligible patients (aged ≥20 Yuankai Shi, J. Au, S. Thongprasert, S. Srinivasan, C. Tsai, M. T. Khoa, K. Heeroma, Y. Itoh, G. Cornelio, Pan‐Chyr Yang +9 moresemanticscholar +1 more sourcePerioperative chemotherapy compared with surgery alone for resectable gastroesophageal adenocarcinoma: an FNCLCC and FFCD multicenter phase III trial.
Journal of Clinical Oncology, 2011 PURPOSE
After curative resection, the prognosis of gastroesophageal adenocarcinoma is poor. This phase III trial was designed to evaluate the benefit in overall survival (OS) of perioperative fluorouracil plus cisplatin in resectable gastroesophageal ...M. Ychou, V. Boige, J. Pignon, T. Conroy, O. Bouché, G. Lebreton, M. Ducourtieux, L. Bedenne, J. Fabre, B. Saint‐Aubert, J. Genève, P. Lasser, P. Rougier +12 moresemanticscholar +1 more sourceCo-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities.
Cancer Discovery, 2015 UNLABELLED
The molecular underpinnings that drive the heterogeneity of KRAS-mutant lung adenocarcinoma are poorly characterized. We performed an integrative analysis of genomic, transcriptomic, and proteomic data from early-stage and chemorefractory lung F. Skoulidis, L. Byers, L. Diao, V. Papadimitrakopoulou, P. Tong, J. Izzo, C. Behrens, H. Kadara, E. Parra, J. R. Canales, Jianjun Zhang, U. Giri, J. Gudikote, M. Cortez, Chaoxu Yang, Youhong Fan, M. Peyton, L. Girard, K. Coombes, C. Toniatti, T. Heffernan, Murim Choi, G. Frampton, V. Miller, J. Weinstein, R. Herbst, Kwok-kin Wong, Jianhua Zhang, Padmanee Sharma, G. Mills, W. Hong, J. Minna, J. Allison, A. Futreal, Jing Wang, I. Wistuba, J. Heymach +36 moresemanticscholar +1 more sourceSubtypes of Pancreatic Ductal Adenocarcinoma and Their Differing Responses to Therapy
Nature Network Boston, 2011 Pancreatic ductal adenocarcinoma (PDA) is a lethal disease. Overall survival is typically 6 months from diagnosis. Numerous phase 3 trials of agents effective in other malignancies have failed to benefit unselected PDA populations, although patients do ...E. Collisson, A. Sadanandam, P. Olson, W. J. Gibb, Morgan L. Truitt, Shenda Gu, J. Cooc, Jennifer Weinkle, Grace E. Kim, L. Jakkula, H. Feiler, A. Ko, A. Olshen, Kathleen Danenberg, M. Tempero, P. Spellman, D. Hanahan, J. Gray +17 moresemanticscholar +1 more sourceThe Circular RNA circPRKCI Promotes Tumor Growth in Lung Adenocarcinoma.
Cancer Research, 2018 Somatic copy number variations (CNV) may drive cancer progression through both coding and noncoding transcripts. However, noncoding transcripts resulting from CNV are largely unknown, especially for circular RNAs.M. Qiu, W. Xia, Rui-Pei Chen, Siwei Wang, Youtao Xu, Zhifei Ma, Weizhang Xu, E. Zhang, Jie Wang, T. Fang, Jing-wen Hu, Gaochao Dong, R. Yin, Jun Wang, Lin Xu +14 moresemanticscholar +1 more sourceMicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma.
Journal of the American Medical Association (JAMA), 2008 CONTEXT
MicroRNAs have potential as diagnostic biomarkers and therapeutic targets in cancer. No study has evaluated the association between microRNA expression patterns and colon cancer prognosis or therapeutic outcome.Aaron J. Schetter, S. Leung, Jane J. Sohn, Krista A. Zanetti, E. Bowman, N. Yanaihara, S. Yuen, T. Chan, D. Kwong, G. Au, Chang-gong Liu, G. Calin, C. Croce, C. Harris +13 moresemanticscholar +1 more sourceGenomic and immune profiling of pre-invasive lung adenocarcinoma
Nature Communications, 2019 Adenocarcinoma in situ and minimally invasive adenocarcinoma are the pre-invasive forms of lung adenocarcinoma. The genomic and immune profiles of these lesions are poorly understood.Haiquan Chen, Jian Carrot-Zhang, Yue Zhao, Haichuan Hu, S. Freeman, Su-Huan Yu, G. Ha, Alison M. Taylor, Ashton C. Berger, Lindsay C. Westlake, Yuanting Zheng, Jiyang Zhang, A. Ramachandran, Q. Zheng, Yunjian Pan, Difan Zheng, Shanbo Zheng, Chao Cheng, Muyu Kuang, Xiaoyan Zhou, Yang Zhang, Hang Li, T. Ye, Yuan Ma, Zhendong Gao, Xiaoting Tao, Han Han, Jun Shang, Ying Yu, Ding Bao, Yechao Huang, Xiangnan Li, Ya-wei Zhang, J. Xiang, Yihua Sun, Yuan Li, A. Cherniack, Joshua D. Campbell, Leming Shi, M. Meyerson +39 moresemanticscholar +1 more sourceProteogenomic characterization of pancreatic ductal adenocarcinoma
Cell, 2021 L. Cao, Chen Huang, D. Zhou, Yingwei Hu, T. M. Lih, Sara R. Savage, Karsten Krug, D. Clark, M. Schnaubelt, Lijun Chen, F. Leprevost, R. V. Eguez, Weiming Yang, Jianbo Pan, Bo Wen, Yongchao Dou, Wen Jiang, Yuxing Liao, Zhiao Shi, Nadezhda V. Terekhanova, Song Cao, Rita Jui-Hsien Lu, Yize Li, Ruiyang Liu, Houxiang Zhu, Peter Ronning, Yige Wu, Matthew A. Wyczalkowski, H. Easwaran, Ludmila V. Danilova, A. Mer, S. Yoo, Joshua M Wang, Wenke Liu, B. Haibe-Kains, M. Thiagarajan, S. Jewell, G. Hostetter, Chelsea J. Newton, Q. K. Li, M. Roehrl, D. Fenyö, Pei Wang, A. Nesvizhskii, D. Mani, G. Omenn, Emily Boja, M. Mesri, A. Robles, H. Rodriguez, O. Bathe, D. Chan, R. Hruban, L. Ding, Bing Zhang, Hui Zhang, Mitual B. Amin, E. An, Christine Ayad, Thomas Bauer, Chet Birger, M. Birrer, S. Boca, William Bocik, M. Borucki, S. Cai, Steve Carr, Sandra R. Cerda, Huan Chen, Steven F. Chen, David W. Chesla, A. Chinnaiyan, A. Colaprico, S. Cottingham, Magdalena Derejska, S. Dhanasekaran, M. Domagalski, B. Druker, Elizabeth Duffy, Maureen A. Dyer, Nathan J. Edwards, M. Ellis, J. Eschbacher, Alicia Francis, Jesse Francis, S. Gabriel, N. Gabrovski, J. Gardner, G. Getz, Michael A. Gillette, C. A. Goldthwaite, Pamela Grady, Shuai Guo, P. Hariharan, Tara Hiltke, B. Hindenach, K. Hoadley, Jasmine Huang, Corbin D. Jones, K. Ketchum, C. Kinsinger, J. Koziak, K. Kuśnierz, Tao Liu, J. Long, D. Mallery, S. Mareedu, R. Matteotti, Nicollette Maunganidze, P. McGarvey, P. Minoo, O. Paklina, A. Paulovich, S. Payne, O. Potapova, B. Pruetz, L. Qi, Nancy V. Roche, K. Rodland, D. Rohrer, E. Schadt, A. Shabunin, T. Shelton, Y. Shutack, Shilpi Singh, Michael V. Smith, Richard D. Smith, L. Sokoll, J. Suh, Ratna R. Thangudu, S. Tsang, K. S. Um, Dana R. Valley, Negin Vatanian, Wenyi Wang, G. Wilson, M. Wiznerowicz, Zhen Zhang, Grace Zhao +138 moresemanticscholar +1 more source