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Adenocarcinoma of the lung [PDF]

open access: bronzeThorax, 1969
The clinical and histological features of 53 cases of adenocarcinoma of the lung are presented. In more than one-third of the patients the tumour was a solitary nodule, raising the possibility that it might be a metastatic focus. Although histological features may suggest an origin from such sources as the kidney, uterus, ovary or bowel, nearly all ...
J. R. Hinds, George Hitchcock
openalex   +4 more sources

Hepatoid Adenocarcinoma of the Lung [PDF]

open access: yesTechnology in Cancer Research & Treatment, 2021
Hepatoid adenocarcinoma of the lung (HAL) is an comparatively rare malignant tumor originating from the lung with shorter survival. HAL morphologically and pathologically exhibits hepatocellular carcinoma (HCC)-like characteristics, while its clinical features resemble pulmonary adenocarcinoma.
Meihui Li, Ying Fan, Hongyang Lu
openaire   +3 more sources

ATF1 promotes the malignancy of lung adenocarcinoma cells by transcriptionally regulating ZNF143 expression

open access: yesActa Biochimica et Biophysica Sinica, 2023
The clinical oncogenic functions and mechanisms of activating transcription factor 1 (ATF1) in the progression of lung adenocarcinoma have not been completely elucidated.
Mei Jinhong   +8 more
doaj   +1 more source

Epidemiological characteristics and risk factors of lung adenocarcinoma: A retrospective observational study from North China

open access: yesFrontiers in Oncology, 2022
BackgroundThe main aim of the study was to determine the risk factors of lung adenocarcinoma and to analyze the variations in the incidence of lung adenocarcinoma according to time, sex, and smoking status in North China.MethodsPatients with lung cancer ...
Daojuan Li   +5 more
doaj   +1 more source

Immune Resistance in Lung Adenocarcinoma [PDF]

open access: yesCancers, 2021
Lung cancer is the leading cancer killer worldwide, imposing grievous challenges for patients and clinicians. The incidence of lung adenocarcinoma (LUAD), the main histologic subtype of lung cancer, is still increasing in current-, ex-, and even non-smokers, whereas its five-year survival rate is approximately 15% as the vast majority of patients ...
Magda Spella, Georgios T. Stathopoulos
openaire   +3 more sources

High GNG4 expression is associated with poor prognosis in patients with lung adenocarcinoma

open access: yesThoracic Cancer, 2022
Background The purpose of this study was to explore the reason for guanine nucleotide binding‐protein gamma subunit‐4 (GNG4) overexpression and the relationship between GNG4 overexpression and the poor prognosis of lung adenocarcinoma (LUAD) patients ...
Bodong Zhou   +7 more
doaj   +1 more source

Expression of MAD2L1 in Lung Adenocarcinoma and Its Effect on Immune Microenvironment

open access: yesZhongliu Fangzhi Yanjiu, 2022
Objective To investigate the expression of MAD2L1 in lung adenocarcinoma and its effect on the prognosis and immune microenvironment of patients. Methods The difference of MAD2L1 expression in lung adenocarcinoma tissue and normal lung tissue was ...
LIU Yingbo   +3 more
doaj   +1 more source

UCHL1 acts as a potential oncogene and affects sensitivity of common anti-tumor drugs in lung adenocarcinoma

open access: yesWorld Journal of Surgical Oncology, 2022
Background Lung adenocarcinoma is the leading cause of cancer death worldwide. Recently, ubiquitin C-terminal hydrolase L1 (UCHL1) has been demonstrated to be highly expressed in many tumors and plays the role of an oncogene.
Jianbo Yao   +9 more
doaj   +1 more source

ARNTL2 is an indicator of poor prognosis, promotes epithelial-to-mesenchymal transition and inhibits ferroptosis in lung adenocarcinoma

open access: yesTranslational Oncology, 2022
Objectives: ARNTL2, as a circadian transcription factor, has been recently proposed to play an important role in a variety of tumors. however, the role of ARNTL2 in lung carcinogenesis and progression remains unclear.
Huan Zhang   +10 more
doaj   +1 more source

Veillonella parvula promotes the proliferation of lung adenocarcinoma through the nucleotide oligomerization domain 2/cellular communication network factor 4/nuclear factor kappa B pathway

open access: yesDiscover Oncology, 2023
Enrichment of Veillonella parvula in the lung microbiota is strongly associated with non-small cell lung cancer (NSCLC) and induces the progression of lung adenocarcinoma in vivo, but its actual role and mechanism remain unexplored.
Wen Zeng   +7 more
doaj   +1 more source

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