Results 31 to 40 of about 478,988 (359)

GMDS knockdown impairs cell proliferation and survival in human lung adenocarcinoma

BMC Cancer, 2018
Background Lung adenocarcinoma is the most common type of lung cancer and one of the most lethal and prevalent cancers. Aberrant glycosylation was common and essential in tumorigenesis, with fucosylation as one of the most common types disrupted in ...
Xing Wei, Kun Zhang, Haifeng Qin, Jinlong Zhu, Qiaoxi Qin, Yang Yu, Hong Wang   +6 more
doaj   +1 more source

Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications. [PDF]

, 2015
Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic behavior and also development, differentiation, growth, and survival.
Helsten, Teresa, Kurzrock, Razelle, Schwaederle, Maria   +2 more
core   +2 more sources

Effects of lncRNA PKD2-2-3 on cell proliferation, clone formation, migration, and invasion of lung adenocarcinoma [PDF]

Zhongguo aizheng zazhi, 2023
Background and purpose: Long non-coding RNA (lncRNA) is abnormally expressed in lung adenocarcinoma patients, and closely related to tumor occurrence, development and chemotherapy resistance.
JIA Liqing, GE Xiaolu, JIANG Lin, ZHOU Xiaoyan
doaj   +1 more source

Modulation of 5-Aminolevulinic acid mediated photodynamic therapy induced cell death in a human lung adenocarcinoma cell line [PDF]

, 2016
Photodynamic therapy (PDT) is a cancer treatment involving the administration of a photosensitising drug which selectively accumulates in tumor tissue, followed by irradiation with appropriate wavelength light.
Battle, A., Diez, Berenice Andrea, Fukuda, Haydee, Teijo, Maria Julieta   +3 more
core   +2 more sources

Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFβ2-bioenergetics-mitochondrial priming. [PDF]

, 2016
The impact of EGFR-mutant NSCLC precision therapy is limited by acquired resistance despite initial excellent response. Classic studies of EGFR-mutant clinical resistance to precision therapy were based on tumor rebiopsies late during clinical tumor ...
Bagai, Rakesh, Bivona, Trever G, Danielpour, David, Feng, Yan, Leahy, Patrick, Lindner, Daniel, Ma, Patrick C, Rosell, Rafael, Shi, Ivy, Thiagarajan, Praveena S, Veigl, Martina, Wu, Xiaoliang, Yin, Lihong, Zhang, Wei, Zhang, Zhenfeng   +14 more
core   +1 more source

DEPDC1 is Highly Expressed in Lung Adenocarcinoma and Promotes Tumor Cell Proliferation

Chinese Journal of Lung Cancer, 2021
Background and objective Lung cancer is the leading cause of death worldwide, and lung adenocarcinoma is the main subtype of lung cancer. DEP domain-containing 1 (DEPDC1) has been proved to be closely related to the occurrence and development of most ...
Jian SHEN, Mengmeng XI
doaj   +1 more source

Dual EGFR inhibition in combination with anti-VEGF treatment: a phase I clinical trial in non-small cell lung cancer. [PDF]

, 2013
BackgroundPreclinical data indicate EGFR signals through both kinase-dependent and independent pathways and that combining a small-molecule EGFR inhibitor, EGFR antibody, and/or anti-angiogenic agent is synergistic in animal models.MethodsWe conducted a ...
Bastida, Christel, Falchook, Gerald S, Fu, Siqing, Hong, David S, Jiang, Yunfang, Kurzrock, Razelle, Morgan-Linnell, Sonia K, Naing, Aung, Piha-Paul, Sarina A, Tsimberidou, Apostolia M, Wheler, Jennifer J, Zinner, Ralph   +11 more
core   +2 more sources

Long noncoding RNA expression profiles of lung adenocarcinoma ascertained by microarray analysis. [PDF]

PLoS ONE, 2014
BACKGROUND:Long noncoding RNAs (lncRNAs) have been shown to be involved in the development and progression of lung cancer. However, the roles of lncRNAs in lung cancer are not well understood.
Gang Xu, Jie Chen, Qinshi Pan, Keta Huang, Jingye Pan, Wenhui Zhang, Jian Chen, Fangyou Yu, Tieli Zhou, Yumin Wang   +9 more
doaj   +1 more source

Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repair [PDF]

, 2011
Jaagsiekte sheep retrovirus (JSRV) is a unique oncogenic virus with distinctive biological properties. JSRV is the only virus causing a naturally occurring lung cancer (ovine pulmonary adenocarcinoma, OPA) and possessing a major structural protein that ...
A Giangreco, A Harris, A Ortin, A Winkelmann, AB Bahnson, AD Miller, AL Payne, AS Zolotukhin, B Chessa, BB Zhou, BJ Bradley, C Cousens, C Johnson, CF Kim, CG Plopper, Claudio Murgia, D Salvatori, DG Miller, DI Nisbet, DW Verwoerd, E Beytut, EL Rawlins, EL Rawlins, F Arnaud, F Arnaud, F Schwenter, G Zavala, Gabriella Di Francesco, H Fan, JA Platt, JA Whitsett, JC DeMartini, JE Donello, JE Visvader, JM Coffin, JM Sharp, JM Sharp, JP Scheerlinck, K McGee-Estrada, K McGee-Estrada, K McGee-Estrada, K Perk, K Quade, L Naldini, LH Rosai JaS, M Bray, M Caporale, M Caporale, M Caporale, M De Las Heras, M De las Heras, M Palmarini, M Palmarini, M Palmarini, M Palmarini, M Palmarini, M Palmarini, M Palmarini, M Palmarini, M Palmarini, Marcelo de las Heras, Marco Caporale, Massimo Palmarini, MF Clarke, MH Kubbutat, Michael Emerman, MJ Holland, N Maeda, N Maeda, N Maeda, N Rosenberg, Nicola Ferri, Ousman Ceesay, P Banerjee, PF Lewis, RM Dakessian, RP Hill, S Zaffran, SK Rai, SK Rai, SK Wootton, SK Wootton, SL Kauffman, SL Liu, SL Liu, SL Liu, SL Liu, T Reya, T Roe, TB Zeltner, TB Zeltner, TE Allen, U O'Doherty, Vincenzo Varasano   +93 more
core   +6 more sources

Overexpression of RhoV Promotes the Progression and EGFR-TKI Resistance of Lung Adenocarcinoma

Frontiers in Oncology, 2021
BackgroundThe Rho GTPase family with ~20 member genes play central roles in a wide variety of cellular processes and tumor cell migration and metastasis.
Hongjin Chen, Ruixue Xia, Long Jiang, Yong Zhou, Haojun Xu, Weiwei Peng, Chengyun Yao, Guoren Zhou, Yijie Zhang, Hongping Xia, Hongping Xia, Hongping Xia, Yongsheng Wang   +12 more
doaj   +1 more source