Results 31 to 40 of about 310,885 (317)
Adenocarcinoma of the lung mimicking interstitial lung disease
Gülhane Tıp DergisiAtypical radiologic and clinical patterns may be observed within subgroups of lung adenocarcinoma. A 74-year-old man with progressive dyspnea and productive cough unresponsive to antibiotherapy showed bilateral interstitial changes in the lung parenchyma
Sümeyye Kodalak Cengiz +3 more
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Lung adenocarcinoma promotion by air pollutants
Nature, 2023 A complete understanding of how exposure to environmental substances promotes cancer formation is lacking. More than 70 years ago, tumorigenesis was proposed to occur in a two-step process: an initiating step that induces mutations in healthy cells, followed by a promoter step that triggers cancer development1.
William Hill +211 more
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Invasive mucinous adenocarcinoma of the lung [PDF]
Translational Cancer Research, 2019 Invasive mucinous adenocarcinoma (IMA) is a unique histological subtype of adenocarcinoma. Due to its low incidence rates, survival data for IMA is scarce and often contradictory. The clinical manifestations of IMA are not precise as compared to other adenocarcinomas, with some patients having bronchial mucus overflow. Difference in immunohistochemical
Chenghui Li, Hongyang Lu, Lu Xu
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Frontiers in Pharmacology, 2022 Tumor microenvironment plays an important role in the development, progression, and prognosis of lung adenocarcinoma. Exploring new biomarkers based on the immune microenvironment of lung adenocarcinoma can effectively predict the prognosis and provide ...
Xin Wang +8 more
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TENET 2.0: Identification of key transcriptional regulators and enhancers in lung adenocarcinoma.
PLoS Genetics, 2020 Lung cancer is the leading cause of cancer-related death and lung adenocarcinoma is its most common subtype. Although genetic alterations have been identified as drivers in subsets of lung adenocarcinoma, they do not fully explain tumor development ...
Daniel J Mullen +8 more
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Papillary Adenocarcinoma: A Rare Subtype of Lung Adenocarcinoma
Cureus, 2023 Papillary adenocarcinoma (PA) of the lung is a specific form of lung cancer characterized by papillary structures in tumor cells. This type of cancer is relatively rare and has distinct pathological and radiological features that differentiate it from other types of lung adenocarcinomas.
Thouil, Afaf +4 more
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FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Expression of CDC20 in lung adenocarcinoma tissues and its effect on the proliferation and invasion of lung adenocarcinoma cells [PDF]
Zhongguo aizheng zazhiBackground and purpose: Lung adenocarcinoma has the characteristics of difficult early detection, rapid tumor progression and low surgical resection rate.
ZHOU Xueqin, LUAN Yanchao, ZHAO Li, RONG Chaochao, YANG Na
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Scientific Reports, 2021 Genetic alterations underlying the development of lung cancer in individuals with idiopathic pulmonary fibrosis (IPF) have remained unclear. To explore whether genetic alterations in IPF tissue contribute to the development of IPF-associated lung cancer,
Yasuto Yoneshima +11 more
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Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source