Results 91 to 100 of about 34,811 (221)
Glucose Metabolism Regulating Colorectal Cancer Initiation and Progression
Cancer Science, Volume 117, Issue 5, Page 1199-1208, May 2026.Drugs and compounds targeting glycolysis in CRC and the mechanisms by which these drugs inhibit their respective targets. ABSTRACT Colorectal cancer (CRC) is one of the most common types of invasive cancer worldwide, which has the characteristics of poor curative effect and poor prognosis. Increasing evidence suggests that hyperactivated glucose uptake
Meiyi Lin, Junpeng Cui
wiley +1 more source
Congenital hypertrophy of the retinal pigment epithelium in Gardner's syndrome
The Pan African Medical Journal, 2014 A 20-year-old woman presented for a routine eye examination. Her best-corrected visual acuity was 20/20 in the right eye and 20/25 in the left eye.
Mina Laghmari, Omar Lezrek
doaj +1 more source
Cell Reports, 2017 Adenomatous polyposis coli (APC) is a polarity regulator and tumor suppressor associated with familial adenomatous polyposis and colorectal cancer development.
Sonia Agüera-González +9 more
doaj +1 more source
In the Beginning There Was Colectomy: Current Surgical Options in Familial Adenomatous Polyposis [PDF]
, 2004 Multiple colonic polyps, almost guaranteed colorectal cancer by the age of forty-five and an increased risk of non-colonic cancers characterise the autosomal dominant condition Familial Adenomatous Polyposis (FAP) 1.
McGrath Daniel R, Spigelman Allan D
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Targeting Inflammation and Immune Regulation in Chronic Inflammation Associated Cancers
Cancer Science, Volume 117, Issue 5, Page 1209-1222, May 2026.Chronic inflammation sustains activation of key inflammatory pathways, including Nuclear factor kappa B (NF‐κB), Interleukin‐6‐signal transducer and activator of transcription 3 (IL6‐STAT3), Phosphoinositide 3‐kinase/Akt (PI3K/Akt), and Wingless/β‐catenin (Wnt/β‐catenin) signaling. This promotes immune dysregulation through the expansion and functional
Lawan Rabiu +5 more
wiley +1 more source
Clinical Endocrinology, Volume 104, Issue 6, Page 682-692, June 2026.
Ram Moorthy +10 more
wiley +1 more source
Beyond the chaos: How architecture structures tumour biology
The FEBS Journal, Volume 293, Issue 9, Page 2519-2540, May 2026.Tissue architecture shapes tumour initiation and progression through multiple interconnected layers continuously remodelled over time. This review outlines how physical forces, biochemical cues, cellular niches and systemic influences contribute to tumour evolution.
Lea Dörner +3 more
wiley +1 more source
Human Pathology: Case Reports, 2018 We report the case of a 57-year-old woman with familial adenomatous polyposis (FAP) who presented with bilateral ovarian microcystic stromal tumors (MCSTs) and a cribriform-morular variant of papillary thyroid carcinoma, as well as concurrent noninvasive
Michelle Stoffel +6 more
doaj +1 more source
Colonic Polyps in Children and Adolescents
Canadian Journal of Gastroenterology, 2007 Colonic polyps most commonly present with rectal bleeding in children. The isolated juvenile polyp is the most frequent kind of polyp identified in children.
Carol A Durno
doaj +1 more source
Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours [PDF]
, 2017 The mutation cluster region (MCR) of adenomatous polyposis coli (APC) is located within the central part of the open reading frame, overlapping with the region encoding the 20 amino acid repeats (20R) that are β-catenin-binding sites.
Behrens, Jürgen +4 more
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