Results 91 to 100 of about 22,051 (209)

Genetics, genomics and clinical features of adenomatous polyposis [PDF]

Adenomatous polyposis syndromes are hereditary conditions characterised by the development of multiple adenomas in the gastrointestinal tract, particularly in the colon and rectum, significantly increasing the risk of colorectal cancer and, in some cases,
Valle, Laura, Joo, Jihoon E., Viana Errasti, Julen, Buchanan, Daniel D.   +3 more
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Clinical outcomes of gastric polyps and neoplasms in patients with familial adenomatous polyposis

Endoscopy International Open, 2017
Background and study aims Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome caused by a germline mutation in the adenomatous polyposis coli (APC) gene, characterized by the presence of more than 100 adenomatous polyps in the ...
Keiko Nakamura, Satoru Nonaka, Takeshi Nakajima, Tatsuo Yachida, Seiichiro Abe, Taku Sakamoto, Haruhisa Suzuki, Shigetaka Yoshinaga, Ichiro Oda, Takahisa Matsuda, Shigeki Sekine, Yukihide Kanemitsu, Hitoshi Katai, Yutaka Saito, Seiichi Hirota   +14 more
doaj   +1 more source

Alcohol consumption, alcohol dehydrogenase 3 polymorphism, and colorectal adenomas. [PDF]

, 2003
Alcohol is a probable risk factor with regard to colorectal neoplasm and is metabolized to the carcinogen acetaldehyde by the genetically polymorphic alcohol dehydrogenase 3 (ADH3) enzyme.
Ocké, Marga C, Wark, P.A., Kok, F.J., Kampman, Ellen, Bunschoten, Annelies, Bunschoten, A., Kok, Frans J., Otten, M.H., Otten, Marten H., Ocké, Marga C., Tiemersma, Edine W, Ocké, M.C., Wark, Petra A, Kampman, E., Tiemersma, Edine W., Wark, Petra A.; id_orcid, Tiemersma, E.W., Otten, Marten H, Kok, Frans J   +18 more
core  

Extracolonic cancer risk in Dutch patients with APC (adenomatous polyposis coli)-associated polyposis [PDF]

, 2017
Background Screening of patients with familial adenomatous polyposis (FAP) have led to a substantial reduction in mortality due to colorectal cancer (CRC).
Langers, AMJ, Ben JM Witteman, Langers, Alexandra Mj, Vasen, Hans F. A., Koornstra, Jan J., Poley, Jan-Werner, Hardwick, James Ch, Witteman, Ben Jm, Ghorbanoghli, Zeinab, Barbara AJ Bastiaansen, Nagengast, F.M., James CH Hardwick, Witteman, Ben J. M., Ghorbanoghli, Z, Dekker, E., Sanduleanu, S, Cappel, Wouter H. de Vos tot Nederveen, Jan J Koornstra, Morreau, H, Hardwick, J.C.H., Silvia Sanduleanu, Koornstra, J.J., Langers, Alexandra M. J., Morreau, H., Vasen, H.F.A., Witteman, BJM, H Morreau, Vasen, Hans Fa, Sanduleanu, S., Nagengast, FM, Vasen, HFA, Hardwick, James C. H., Evelien Dekker, Jan-Werner Poley, Hans FA Vasen, Nagengast, Fokko M., Cappel, W, Langers, A.M.J., Bastiaansen, BAJ, Ghorbanoghli, Z., Bastiaansen, Barbara A. J., Alexandra MJ Langers, Fokko M Nagengast, de Vos tot Nederveen Cappel, Wouter H., Zeinab Ghorbanoghli, Poley, J.W., Hardwick, JCH, Witteman, B.J.M., Sanduleanu, Silvia, Bastiaansen, B.A.J., Cappel, W.H.D.T.N., Koornstra, JJ, Dekker, Evelien, Dekker, E, Bastiaansen, Barbara Aj, Wouter H de Vos tot Nederveen Cappel   +55 more
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Evaluation and Management of Thyroid Nodules: A Joint Consensus Statement From the British Thyroid Association (BTA), British Association of Endocrine and Thyroid Surgeons (BAETS) and Collaborating Bodies

Clinical Endocrinology, Volume 104, Issue 6, Page 682-692, June 2026.
Ram Moorthy, Saba P. Balasubramanian, Kate Farnell, Mairead Kelly, Gitta Madani, Mufaddal Moonim, Carla Moran, Julia Priestley, Michael Stechman, Emma Watts, Kristien Boelaert   +10 more
wiley   +1 more source

A porcine model of familial adenomatous polyposis.

, 2012
We created gene-targeted pigs with mutations in the adenomatous polyposis coli (APC) gene (APC) that are orthologous to those responsible for human familial adenomatous polyposis (FAP).
Flisikowska, T;Merkl, C;Landmann, M;Eser, S;Rezaei, N;Cui, X;Kurome, M;Zakhartchenko, V;Kessler, B;Wieland, H;Rottmann, O;Schmid, RM;Schneider, G;Kind, A;Wolf, E;Saur, D;Schnieke, A, Flisikowska, Tatiana;Merkl, Claudia;Landmann, Martina;Eser, Stefan;Rezaei, Nousin;Cui, Xinxin;Kurome, Mayuko;Zakhartchenko, Valeri;Kessler, Barbara;Wieland, Hagen;Rottmann, Oswald;Schmid, Roland M.;Schneider, Günter;Kind, Alexander;Wolf, Eckhard;Saur, Dieter;Schnieke, Angelika   +1 more
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An uncommon intersection: Familial adenomatous polyposis and solid pseudopapillary neoplasm of the pancreas: A case report and review of the literature

Radiology Case Reports
The co-occurrence of both Familial Adenomatous Polyposis (FAP) and Solid Pseudopapillary Neoplasms (SPN) of the pancreas is extremely uncommon, with limited reports published in the literature. FAP is a rare inherited disorder caused by a mutation in the
Hajra Arshad, Charles K. Crawford, Elliot K. Fishman   +2 more
doaj   +1 more source

Recurrent Fistula between Ileal Pouch and Vagina—Successful Treatment with a Gracilis Muscle Flap

Case Reports in Medicine, 2009
Fistulae between an ileal pouch and the vagina are an uncommon complication of ileal pouch-anal anastomosis following proctocolectomy and mucosectomy in patients with familial adenomatous polyposis coli.
Feride Aydin, Claus Ferdinand Eisenberger, Andreas Raffel, Alexander Rehders, Stefan Benedikt Hosch, Wolfram Trudo Knoefel   +5 more
doaj   +1 more source

Increased colorectal cancer incidence in obligate carriers of heterozygous mutations in MUTYH

, 2002
Background & Aims: MUTYH-associated polyposis (MAP) is an autosomal recessive disorder caused by mutations in the MUTYH gene. Patients with MAP are at extremely high risk of colorectal cancer, but the risks of colorectal and other cancers in ...
Jones, Natalie, Maher, Eamonn, Sampson, Julian Roy, Edwards, Emma, Christian, Daria, Evans, D Gareth, Vasen, Hans F., Wark, Petra A., Sampson, Julian R, Eccles, Diana, Aretz, Stefan, Nielsen, Maartje, Maher, Eamonn R., Wark, Petra A, Vogt, Stefanie, Wark, Petra A.; id_orcid, Hes, Frederik J, Hes, Frederik J., Evans, D. Gareth, Sampson, Julian R., Vasen, Hans F, Maher, Eamonn R   +21 more
core   +1 more source

A New Germline Stop Codon Mutation in Exon 15 of the Gene Predisposing to Familial Adenomatous Polyposis

The International Journal of Biological Markers, 2013
Familial adenomatous polyposis (FAP) is an autosomal dominant disorder related to germline mutations of the adenomatous polyposis coli ( APC ) gene. It is characterized by the detection of numerous adenomatous polyps that, if untreated, develop into ...
Laura Schirosi, Marcello Pellegrino, Paolo Tarantino, Salvatore Mauro, Andrea Tinelli, Marilena Greco PhD   +5 more
doaj   +1 more source