Results 101 to 110 of about 22,051 (209)

Peripheral nerve sheath tumors in the head and neck in patients with APC gene deletion mutations: a case report and scoping review of the literature [PDF]

Clinical and Experimental Pediatrics
Adenomatous polyposis coli (APC) is a tumor suppressor gene expressed throughout the body. APC mutations increase the risk of malignancy and are often characterized by syndromes that encompass a spectrum of neoplastic manifestations, such as familial ...
Koral M. Blunt, Monirah Albathi, Miriam Conces, Tendy Chiang   +3 more
doaj   +1 more source

Hereditary non-polyposis colorectal carcinoma (HNPCC) : morphological and immunohistochemical studies

, 2005
Includes bibliographical references.Families with hereditary non-polyposis colorectal carcinoma (HNPCC) are not uncommon along the West-Coast of South Africa.
Holm, Hannes
core  

The adenomatous polyposis coli (APC) tumour suppressor--genetics, function and disease.

, 2000
Mutations in the adenomatous polyposis coli (APC) gene are the basis of familial adenomatous polyposis and the majority of sporadic colorectal cancer.
Lamlum, H, Tomlinson, IP, Sieber, OM
core   +1 more source

Multidisciplinary management and genetic findings in an Ashkenazi Jewish male: case report of pathogenic BRCA2 and adenomatous polyposis coli mutations

Academia Oncology
This case report describes the multidisciplinary management and genetic findings of a 66-year-old Ashkenazi Jewish male with a history of thyroid cancer who was diagnosed with muscle-invasive bladder cancer (MIBC) and invasive human epidermal ...
Daniela Guevara, Majd Assaad, Jyothi Manohar, Michael Sigouros, John Otilano, Abigail King, Christina Fedorov, Anna Butusova, Arina Aghajanyan, Valentin Channov, Alexandra Boyko, Olivier Elemento, Juan Miguel Mosquera, Cora N. Sternberg   +13 more
doaj   +1 more source

Ficus Ficus Exasperata Suppresses Early Events in Colorectal Carcinogenesis by Down Regulating the Expression of Beta-Catenin, Enhancing Adenomatous Polyposis Coli and Boosting the Immune System.

Journal of Experimental and Molecular Biology
Wingless (Wnt) signaling is a cascade known in the regulation of development and physiology. Abnormalities in the components of the Wnt/β-catenin signaling pathway have been a major cause of cancer especially in colorectal cancer (CRC).
Olayemi Mujidat Olude
doaj   +1 more source

Trabid patient mutations impede the axonal trafficking of adenomatous polyposis coli to disrupt neurite growth. [PDF]

Elife, 2023
Frank D, Bergamasco M, Mlodzianoski MJ, Kueh A, Tsui E, Hall C, Kastrappis G, Voss AK, McLean C, Faux M, Rogers KL, Tran B, Vincan E, Komander D, Dewson G, Tran H.   +15 more
europepmc   +1 more source

An immunohistochemical study of beta-catenin in HNPCC colon tumours

, 2004
Includes bibliographical references (leaves 49-55).Beta-catenin is normally complexed with adenomatous polyposis coli (APC) protein and E-cadherin adhesion molecule, and localized on the cell membrane.
Watkins, Jennifer G
core  

Familial adenomatous polyposis: Diagnosis and surveillance strategies: Review article

, 2020
Familial adenomatous polyposis is characterized by over 100 colorectal adenomas in the colorectum. The disease equally affects both sexes, with an incidence estimated at 1.14025-1.8300.
Jokar, M.H., Aghaei, M., Mohamadkhani, A., Sedighi, S., Moradzadeh, M.   +4 more
core  

The Tumor Suppressor Adenomatous Polyposis Coli (apc) Is Required for Neural Crest-Dependent Craniofacial Development in Zebrafish. [PDF]

J Dev Biol, 2023
Liu X, Jones WD, Quesnel-Vallières M, Devadiga SA, Lorent K, Valvezan AJ, Myers RL, Li N, Lengner CJ, Barash Y, Pack M, Klein PS.   +11 more
europepmc   +1 more source

Valor de la ortopantomografía en la poliposis familiar de colon

Revista Cubana de Medicina, 1996
El hecho de existir entre nuestros pacientes varias familias con poliposis cólica familiar nos motivó a realizarles estudios panorámicos de mandíbula, en busca de osteomas.
Graciela Jiménez Mesa, María Aurora López Barbán, Olga Hano García   +2 more
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