Results 171 to 180 of about 34,811 (221)

Pouch cancer in familial adenomatous polyposis. Incidence, risk factors and literature review: a propos of three rare cases. [PDF]

open access: yesArq Bras Cir Dig
Campos FG   +6 more
europepmc   +1 more source

Profuse familial adenomatous polyposis with an Adenomatous Polyposis Coli exon 3 mutation

Familial Cancer, 2001
The attenuated form of familial adenomatous polyposis coli (AAPC) is associated with mutations in the adenomatous polyposis coli (APC) gene which cluster in the 5' region of the gene. It has been proposed that a 'genotype-phenotype boundary' exists at codons 159-163, and mutations that are 5' of this boundary will produce AAPC.
S, Nasioulas   +5 more
openaire   +2 more sources

Presymptomatic diagnosis of familial adenomatous polyposis coli

Diseases of the Colon & Rectum, 1994
Familial adenomatous polyposis (FAP), an autosomal dominant inherited disease, confers a high risk of colon cancer, and recently the gene responsible for FAP, termed adenomatous polyposis coli (APC) gene, was identified and fully characterized.For the presymptomatic diagnosis of FAP, we have performed linkage studies using two polymorphic systems close
J G, Park   +3 more
openaire   +2 more sources

Dental anomalies in familial adenomatous polyposis coli

Acta Odontologica Scandinavica, 1987
Forty-seven Danish and 50 Finnish patients with familial adenomatous polyposis coli (FPC) were studied by panoramic tomography (PTG) of the mandible, which showed dental abnormalities in 17% of the cases. Eleven patients (11%) had supernumerary teeth and/or compound osteomas, and nine patients (9%) had impacted permanent teeth.
J O, Søndergaard   +5 more
openaire   +2 more sources

Adenomatous polyposis coli proteins and cell adhesion

Current Opinion in Cell Biology, 2004
Adenomatous polyposis coli (APC) is an important tumour suppressor in the mammalian intestinal epithelium. It binds to beta-catenin and its role as a tumour suppressor depends predominantly on its ability to downregulate soluble beta-catenin, a key effector of the Wnt signalling pathway.
Mariann, Bienz, Fumihiko, Hamada
openaire   +2 more sources

Unusual adenomatous polyps in juvenile polyposis coli

The American Journal of Surgical Pathology, 1982
A 14-year-old boy had an ileocolectomy for juvenile polyposis coli. Twenty-five years later he developed peculiar adenomatous polyps in his rectum. The polyps had irregularly shaped glands lined by cells with stratified, atypical nuclei. Some glands were distended with mucus, but otherwise the polyps did not resemble juvenile polyps. Two other types of
S E, Mills, R E, Fechner
openaire   +2 more sources

Adenomatous polyposis coli and translational medicine

The Lancet, 1996
See page 433 Advances in molecular biological techniques in recent years have greatly increased our level of understanding about the mechanisms underlying carcinogenesis. Such advances have also enabled identification of genetic mutations associated with specific cancers.
openaire   +2 more sources

Adenomatous polyposis coli gene large deletions in Iranian patients with familial adenomatous polyposis

Indian Journal of Cancer, 2014
Context: Familial adenomatous polyposis (FAP) is one type of hereditary colon cancer with a large number of precancerous polyps that initiation to growth in childhood and adolescent. Mutation in adenomatous polyposis coli (APC) gene is the cause of FAP.
R, Kishani Farahani   +7 more
openaire   +2 more sources

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