Results 91 to 100 of about 24,916 (232)
Cancer Cell International, 2022 Background Colon cancer is often driven by mutations of the adenomatous polyposis coli (APC) gene, an essential tumor suppressor gene of the Wnt β-catenin signaling pathway. APC and its cytoplasmic interactions have been well studied.
Nayra M. Al-Thani +4 more
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Cells, 2023 The Wnt signaling pathway is a highly conserved regulator of metazoan development and stem cell maintenance. Activation of Wnt signaling is an early step in diverse malignancies.
Chenchen Li +3 more
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Cell Biochemistry and Function, Volume 44, Issue 7, July 2026.ABSTRACT Photobiomodulation (PBM) has gained recognition as a promising, non‐invasive strategy to enhance the differentiation of adipose‐derived stem cells (ADSCs) into smooth muscle cells (SMCs), particularly when used together with a three‐dimensional (3D) hydrogel culture system.
Christevie Mbuyu +2 more
wiley +1 more source
MACF1 promotes preosteoblast migration by mediating focal adhesion turnover through EB1
Biology Open, 2020 Microtubule actin crosslinking factor 1 (MACF1) is a widely expressed cytoskeletal linker and plays an essential role in various cells’ functions by mediating cytoskeleton organization and dynamics.
Peihong Su +7 more
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International Journal of Cancer, Volume 159, Issue 1, Page 144-158, 1 July 2026.What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho +7 more
wiley +1 more source
Neuronal Nicotinic Synapse Assembly Requires the Adenomatous Polyposis Coli Tumor Suppressor Protein [PDF]
The Journal of Neuroscience, 2004 Normal cognitive and autonomic functions require nicotinic synaptic signaling. Despite the physiological importance of these synapses, little is known about molecular mechanisms that direct their assembly during development. We show here that the tumor-suppressor protein adenomatous polyposis coli (APC) functions in localizing α3 ...
Murali Krishna, Temburni +4 more
openaire +2 more sources
Scientific Reports, 2021 Adenomatous polyposis coli (APC) is a tumor-suppressing protein whose inactivation triggers the formation of colorectal polyps. Numerous studies using cell lines or genetically engineered mice have revealed its role in suppressing Wnt/β-catenin signaling
Daisuke Yamazaki +4 more
doaj +1 more source
Chemical and Technological Aspects of Magnetic Particles for Cancer Liquid Biopsy Applications
ChemistryOpen, Volume 15, Issue 7, July 2026.Magnetic bead engineering for liquid biopsy diagnostics reviews advances in magnetic bead design for the selective enrichment of circulating tumor DNA (ctDNA), circulating tumor cells (CTCs), and extracellular vesicles (EVs) from complex biofluids.
Beatriz Naranjo‐Martínez +9 more
wiley +1 more source
Desmoplastic fibroma of the mandible: a rare gnathic bone tumor with a review of the literature
Autopsy and Case Reports, 2019 Desmoplastic fibroma (DF) is a rare bone tumor, which is known to involve mostly the gnathic bones. In this setting, the clinical presentation is usually represented by a bulging tumor of the face. Radiologically, the tumor is usually characterized by an
Manoj Gopal Madakshira +2 more
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A specific upregulated long noncoding RNA in colorectal cancer promotes cancer progression
JCI Insight, 2022 Long noncoding RNA (lncRNA) plays a crucial role in the pathogenesis of various diseases, including colorectal cancer (CRC). The gene mutations of adenomatous polyposis coli (APC) were found in most patients with CRC.
Junshu Li +18 more
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