Results 121 to 130 of about 24,916 (232)

Role of the Wnt/β-catenin signaling pathway in the development of HCC

Frontiers in Immunology
Abnormalities in the Wnt/β-catenin pathway promote the development of hepatocellular carcinoma (HCC). Mutations in CTNNB1, which encodes β-catenin, are frequently found in clinical HCC samples, as are loss-of-function mutations in signaling pathway ...
Bo Lin, Mengsen Li, Mengsen Li
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Mutations in APC, CTNNBI and K-ras genes and expression of hMLHI in sporadic colorectal carcinomas from the Netherlands Cohort Study [PDF]

, 2005
22.08.14 KB.
de Goeij, AFPM, de Bruïne Adriaan P, Luchtenborg, M, Saritas A Merdan, van Muijen, Goos NP, Saritas, AM, Weijenberg, MP, van Muijen, GNP, Saritas, A.M., Weijenberg, Matty P., Piet A van den Brandt, Roemen, GMJM, Adriaan P de Bruïne, de Goeij, Anton F P M, Wark, P.A., de Goeij Anton FPM, van Muijen, G.N.P., de Bruine, AP, de Bruine, A.P., Anton FPM de Goeij, de Bruïne, Adriaan P., Matty P Weijenberg, Lüchtenborg, Margreet, Margreet Lüchtenborg, van Muijen Goos NP, Roemen, G.M., A Merdan Saritas, Roemen, Guido M J M, Brandt, P.A. van den, Saritas, A. Merdan, Wark, PA, Wark Petra A, Muijen, G.N.P. van, Saritas, A Merdan, van den Brandt, Piet A, Weijenberg Matty P, Wark, Petra A.; id_orcid, van den Brandt, PA, Goos NP van Muijen, Weijenberg, Matty P, Roemen, G.M.J.M., van den Brandt, Piet A., de Bruïne, Adriaan P, van den Brandt Piet A, Guido MJM Roemen, de Goeij, Anton FPM, Lüchtenborg Margreet, Merdan Saritas, M., Bruine, A.P. de, van den Brandt, P.A., Luchtenborg, M., Goeij, A.F. de, Weijenberg, M.P., Wark, Petra A, Roemen Guido MJM, Roemen, Guido MJM, Petra A Wark, de Goeij, A.F., van Muijen, Goos N P   +58 more
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Familial adenomatous polyposis: Diagnosis and surveillance strategies: Review article

, 2020
Familial adenomatous polyposis is characterized by over 100 colorectal adenomas in the colorectum. The disease equally affects both sexes, with an incidence estimated at 1.14025-1.8300.
Jokar, M.H., Aghaei, M., Mohamadkhani, A., Sedighi, S., Moradzadeh, M.   +4 more
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Hereditary non-polyposis colorectal carcinoma (HNPCC) : morphological and immunohistochemical studies

, 2005
Includes bibliographical references.Families with hereditary non-polyposis colorectal carcinoma (HNPCC) are not uncommon along the West-Coast of South Africa.
Holm, Hannes
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An immunohistochemical study of beta-catenin in HNPCC colon tumours

, 2004
Includes bibliographical references (leaves 49-55).Beta-catenin is normally complexed with adenomatous polyposis coli (APC) protein and E-cadherin adhesion molecule, and localized on the cell membrane.
Watkins, Jennifer G
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Doctor of Philosophy

, 2007
dissertationThe Adenomatous Polyposis Coli (APC) tumor suppressor gene is responsible for an inherited predisposition to colon cancer through the development of multiple colorectal adenomas.
Logan, Jennifer Sue
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Regulation of cell migration by dynamic microtubules [PDF]

, 2011
Microtubules define the architecture and internal organization of cells by positioning organelles and activities, as well as by supporting cell shape and mechanics. One of the major functions of microtubules is the control of polarized cell motility.
Irina Kaverina, Anne Straube, Kaverina, Irina, Straube, Anne   +3 more
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Large Extent of Disorder in Adenomatous Polyposis Coli Offers a Strategy to Guard Wnt Signalling against Point Mutations

, 2013
Mutations in the central region of the signalling hub Adenomatous Polyposis Coli (APC) cause colorectal tumourigenesis. The structure of this region remained unknown.
Rüdiger, Stefan G. D., Sub Crystal and Structural Chemistry, Maurice, Madelon M., Sub Cellular Protein Chemistry, Radli, Martina, Forneris, Federico, Minde, David P., Cellular Protein Chemistry   +7 more
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Molecular and clinical characteristics in 32 families affected with familial adenomatous polyposis

, 2001
Germ-line mutations in the 5' half of the Adenomatous Polyposis Coli (APC) gene are found in about 80% of the patients affected with familial adenomatous polyposis (FAP). The vast majority of these are nonsense or frameshift mutations which result in the
Couturier, A., Membrez, V, Chappuis, P. O., Couturier, A, Delozier-Blanchet, C., Soravia, C., Schorderet, D F, Soravia, Claudio, Hutter, Pierre, Membrez, V., Chappuis, Pierre, Rey-Berthod, C, Joris, F., Murphy, Anne Elisabeth, Delozier-Blanchet, C, Joris, F, Hutter, P., Rey-Berthod, C., Murphy, A., Schorderet, D. F.   +19 more
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Immunoprophylaxie des cancers colorectaux par des glucides indigestibles fermentables : études chez la souris Min [PDF]

, 1999
Certaines fibres alimentaires réduiraient l'apparition des cancers colorectaux mais l'hypothèse reste controversée. Un des mécanismes fait intervenir la production par fermentation de butyrate.
Pierre, Fabrice, Pierre, Fabrice H.F.
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