Results 181 to 190 of about 617,017 (357)

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

open access: yesAdvanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen   +11 more
wiley   +1 more source

Contrasting functions of CD73 and adenosine in CD8+ T-cell exhaustion during antitumor immunity. [PDF]

open access: yesOncoimmunology
Saavedra-Almarza J   +15 more
europepmc   +1 more source

Adenosine Receptors

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2011
openaire   +2 more sources

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

open access: yesAdvanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang   +7 more
wiley   +1 more source

On-chip selection of adenosine aptamer using graphene oxide-coated magnetic nanoparticles

open access: green, 2022
Hosub Lim   +7 more
openalex   +2 more sources

Oncostatin M upregulates CD73 via the MAPK pathway in keratinocytes to promote an adenosine-dependent anti-inflammatory response in psoriasis. [PDF]

open access: yesFront Immunol
Giraulo C   +8 more
europepmc   +1 more source

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