Results 161 to 170 of about 486,199 (215)

Adenosine and adenosine receptors in colorectal cancer

International Immunopharmacology, 2020
CD39 (nucleoside triphosphate diphosphohydrolase) and Ecto-5-nucleotidase (CD73) have been recognized as important factors mediating various pathological and physiological responses in the tumor microenvironment. Elevated expression of CD73 and CD39 is correlated with the over-production of adenosine in the tumor region.
Farnaz, Hajizadeh, Ali, Masjedi, Sima, Heydarzedeh Asl, Fariba, Karoon Kiani, Makwan, Peydaveisi, Ghasem, Ghalamfarsa, Farhad, Jadidi-Niaragh, Andrey, Sevbitov   +7 more
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Adenosine and Adenosine Receptors

American Journal of Respiratory Cell and Molecular Biology, 1990
In the last decade, there has been renewed interest in extracellular signaling by adenosine and adenine nucleotides. The potent cardiovascular effects of these agents were originally described by Drury and Szent-Gy6rgyi in 1929 (1). This report was followed by a flurry of interest in the use of adenosine as an antihypertensive agent, which subsided ...
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Adenosine Receptors

Annual Review of Physiology, 1992
Our knowledge of A1 and A2ARs has grown dramatically since they were first defined by Burnstock. With the recent purification of the A1AR and the cDNA cloning of the A2AR, an even more rapid expansion of information regarding their structure, function, and regulation should now ensue.
M E, Olah, G L, Stiles
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Cardioprotective actions of adenosine and adenosine analogs

1996
Adenosine contributes to the physiological regulation of cardiovascular function and it clearly plays important roles under pathophysiological conditions. The nucleoside functions intracellularly as a major contributor to the general cellular economy and extracellularly as an important signalling molecule.
M A, Cook, M, Karmazyn
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