Results 201 to 210 of about 734,488 (357)

Seipin‐Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu, Junxia Zhang, Yusi Chen, Geng Shen, Yufei Han, Zihao Zhou, Jinxuan Chen, Xuya Kang, Huilin Qu, Jiaxin Duanmu, Haibao Shang, Yingjia Li, Wei Huang, Yan Zhang   +13 more
wiley   +1 more source

Caffeine Mitigates Adenosine-Mediated Angiogenic Properties of Choroidal Endothelial Cells Through Antagonism of A₁ Adenosine Receptor and PI3K-AKT Axis. [PDF]

Cells
Park S, Song YS, Feng X, Sorenson CM, Sheibani N.   +4 more
europepmc   +1 more source

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

Hypoxia as a Central Regulator of Plasma Membrane Phosphohydrolase Enzymes: Possible Roles in Extracellular Phosphate Generation and Adenosine Metabolism. [PDF]

Membranes (Basel)
de Oliveira PHS, Silva-Freitas BB, Meyer-Fernandes JR, Lacerda-Abreu MA.   +3 more
europepmc   +1 more source

Discovery of a potent, selective, and tumor-suppressing antibody antagonist of adenosine A2A receptor

Linya Wang, Pankaj Garg, Kara Y. Chan, Tom Z. Yuan, Ana González Hernández, Zhen Han, Sean M. Peterson, Emily Tuscano, Crystal Safavi, Eric Kwan, Mouna Villalta, Melina Mathur, Joyce Lai, Fumiko Axelrod, Colby Souders, Chloe Emery, Aaron K. Sato   +16 more
openalex   +2 more sources

AB204. Research on adenosine signal in renal fibrosis originated from unilateral ureteral obstruction

, 2014
Bing Xia, Yuxin Tang
openalex   +1 more source

Adenosine Receptors

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2011
openaire   +2 more sources

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source

Adenosine in human atrial fibrillation modulates and re-distributes atria-wide dominant frequencies and directs to reentry ablation sites with improved outcome. [PDF]

Sci Rep
Calvo D, Salinas L, Martínez-Camblor P, Salgado M, Álvarez-Velasco R, Martínez-León A, Soroa M, García-Iglesias D, Filgueiras-Rama D, Gonzalez-Ferrer JJ, Cañadas V, Salgado R, Cruz A, Quintanilla J, Redondo A, Rodrigo M, Pérez-Villacastín J, Pérez-Castellano N, Berenfeld O.   +18 more
europepmc   +1 more source

Effects of rapid administration of adenosine triphosphate in patients with symptomatic bradycardia

, 1990
Hiroshi Yoshimura, Toshiyuki Ishikawa, S. Hayashi, Hideyuki Yakuwa, Toshio Sano, TOYO NIHEI, Masao Ishii   +6 more
openalex   +1 more source