Ion gradients and the accumulation of various amino acids by mouse ascites-tumour cells depleted of adenosine of adenosine triphosphate [PDF]
Allison A. Eddy+2 more
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Multiple therapeutic modalities combined in a synergistic way that can modulate different immune axes are demonstrated potentially effective in boosting immunotherapy. A nucleic acid‐locked smart carrier (NASC) performed as an “all‐in‐one” nanoplatform is constructed for efficient eliciting chemo‐ and photothermal‐amplified immunogenic cell death to ...
Jiayang Zhang+6 more
wiley +1 more source
Astrocytes at the heart of sleep: from genes to network dynamics. [PDF]
Bellier F+5 more
europepmc +1 more source
The adenylate kinase of human plasma, erythrocytes and platelets in relation to the degradation of adenosine diphosphate in plasma [PDF]
RJ HASLAM, D. C. B. Mills
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During the G2/M phase, mucin1 (MUC1) activates protein phosphatase 2A (PP2A), leading to reduced phosphorylation of protein kinase C ζ (PKCζ) and NUMB, which promotes symmetric division and expansion of cancer stem‐like cells (CSLCs), thereby driving tumorigenesis. Combined inhibition of the MUC1–PP2A axis using LB100/GO203 with etoposide restores PKCζ
Shengze Li+15 more
wiley +1 more source
Adenosine receptor subtype modulators: Insight into molecular mechanisms and their therapeutic application. [PDF]
Solanki N+14 more
europepmc +1 more source
Some properties of a kidney adenosine triphosphatase relevant to active cation transport [PDF]
KP Wheeler, R. Whittam
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Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu+9 more
wiley +1 more source
SAM transmethylation pathway and adenosine recycling to ATP are essential for systemic regulation and immune response. [PDF]
Nedbalová P+4 more
europepmc +1 more source
The biological significance of the linkages in adenosine triphosphoric acid
J. H. Gillespie
openalex +2 more sources