Results 271 to 280 of about 869,856 (392)

Pancreatic Cancer‐Derived Extracellular Vesicles Enriched with miR‐223‐5p Promote Skeletal Muscle Wasting Associated with Cachexia

Advanced Science, EarlyView.
EVs and EV‐microRNAs (miRNAs) mediate PDAC‐skeletal muscle communication. miR‐223‐5p reduces METTL14 transcription by targeting MAFA, which subsequently decreases m6A methylation in skeletal muscles, ultimately leading to muscle wasting. This study highlights the absorption of miRNA in PDAC‐derived EVs by skeletal muscles and reveals a previously ...
Kangjing Xu, Rongxi Shen, Li Zhang, Xuejin Gao, Xinbo Wang, Changhua Zhang, Xi Chen, Xinying Wang   +7 more
wiley   +1 more source

Valerenic Acid and Pinoresinol as Positive Allosteric Modulators: Unlocking the Sleep-Promoting Potential of Valerian Extract Ze 911. [PDF]

Molecules
Senn R, Schertler L, Bussmann H, Drewe J, Boonen G, Butterweck V.   +5 more
europepmc   +1 more source

HISTOCHEMICAL DEMONSTRATION OF MITOCHONDRIAL ADENOSINE TRIPHOSPHATASE ACTIVITY IN TISSUE SECTIONS [PDF]

, 1962
M. Wachstein, MAIRE BRADSHAW, José Ortíz   +2 more
openalex   +1 more source

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

Nature reviews. Drug discovery, 2006
G. Haskó, J. Linden, B. Cronstein, P. Pacher   +3 more
semanticscholar   +1 more source

Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis

Advanced Science, EarlyView.
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves, Darius Lane, Adam Wahida, Md. Jakaria, Pawel Kalinowski, Adam Southon, Abdel Ali Belaidi, Teresa Samperi‐Esteve, Triet Phu Minh Nguyen, Peng Lei, Marcus Krueger, Stefan Mueller, Marcus Conrad, Puja Agarwal, Sue E Leurgans, Julie Schneider, Ashley I. Bush, Scott Ayton   +17 more
wiley   +1 more source

Structural basis for the substrate specificity of Helix pomatia AMP deaminase and a chimeric ADGF adenosine deaminase. [PDF]

J Biol Chem
Kaur G, Horton JR, Tzertzinis G, Zhou J, Schildkraut I, Cheng X.   +5 more
europepmc   +1 more source

CHANGE DUE TO AGING OF POTASSIUM CONTENT, CARBONIC ANHYDRASE AND HEMOLYSIS OF THE COLD STORED HUMAN ERYTHROCYTE, AND EFFECT OF SOME GLUCIDES, THIOL COMPOUNDS AND ADENOSINE TRIPHOSPHATE ON THEM

, 1959
EIIGHI KIKKAWA, K Kuriaki
openalex   +1 more source

GHSR‐Foxo1 Signaling in Macrophages Promotes Liver Fibrosis via Inflammatory Response and Hepatic Stellate Cell Activation

Advanced Science, EarlyView.
Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim, Quan Pan, Zeyu Liu, Weiqi Ai, Hye Won Han, Sakhila K. Banu, Robert Y.L. Tsai, Gus A. Wright, Shaodong Guo, Yuxiang Sun   +9 more
wiley   +1 more source

Research progress of CD73-adenosine signaling regulating hepatocellular carcinoma through tumor microenvironment. [PDF]

J Exp Clin Cancer Res
Shan L, Gong M, Zhai D, Meng X, Liu J, Lv X.   +5 more
europepmc   +1 more source

Further Studies on Chloroplast Adenosine Triphosphatase Activation by Acid-Base Transition

, 1968
Jack H. Kaplan, André T. Jagendorf
openalex   +1 more source