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Oncogenic RAS activity is linked to immune priming and adenosine-driven immune evasion in lung adenocarcinoma

de Carné Trécesson S, East P, Pillsbury CE, dos Santos MS, Cha H, Colliver E, Gilmore T, Rana S, Moore C, Lighterness S, Caswell D, Boumelha J, Tomaschko M, Baer R, Eyles J, Teixeira B, Saeed M, Litchfield K, Molina-Arcas M, Lee S, MacRae JI, Hobson P, Swanton C, Downward J.   +23 more
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Adenosine and Adenosine Receptors

American Journal of Respiratory Cell and Molecular Biology, 1990
In the last decade, there has been renewed interest in extracellular signaling by adenosine and adenine nucleotides. The potent cardiovascular effects of these agents were originally described by Drury and Szent-Gy6rgyi in 1929 (1). This report was followed by a flurry of interest in the use of adenosine as an antihypertensive agent, which subsided ...
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Adenosine Receptors

Annual Review of Physiology, 1992
Our knowledge of A1 and A2ARs has grown dramatically since they were first defined by Burnstock. With the recent purification of the A1AR and the cDNA cloning of the A2AR, an even more rapid expansion of information regarding their structure, function, and regulation should now ensue.
M E, Olah, G L, Stiles
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Adenosine transporters

General Pharmacology: The Vascular System, 1996
1. In mammals, nucleoside transport is an important determinant of the pharmacokinetics, plasma and tissue concentration, disposition and in vivo biological activity of adenosine as well as nucleoside analogues used in antiviral and anticancer therapies. 2.
J A, Thorn, S M, Jarvis
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Adenosine and adenosine receptors in colorectal cancer

International Immunopharmacology, 2020
CD39 (nucleoside triphosphate diphosphohydrolase) and Ecto-5-nucleotidase (CD73) have been recognized as important factors mediating various pathological and physiological responses in the tumor microenvironment. Elevated expression of CD73 and CD39 is correlated with the over-production of adenosine in the tumor region.
Farnaz, Hajizadeh, Ali, Masjedi, Sima, Heydarzedeh Asl, Fariba, Karoon Kiani, Makwan, Peydaveisi, Ghasem, Ghalamfarsa, Farhad, Jadidi-Niaragh, Andrey, Sevbitov   +7 more
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Adenosine Diphosphate, Adenosine Triphosphate

1955
The increasing importance for animals and bacteria of adenosine diphosphate (ADP) and adenosine triphosphate (ATP) in energy-transfer mechanisms involving such widely diverse processes as muscular contraction, nerve conduction, fire fly luminescence, coenzyme syntheses, tumor growth, polysaccharide synthesis and many other key reactions (McElroy and ...
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