Results 31 to 40 of about 712,877 (361)
Blocking Adenosine/A2AR Pathway for Cancer Therapy
Chinese Journal of Lung Cancer, 2022 Adenosine is a metabolite produced abundantly in the tumor microenvironment, dampening immune response in inflamed tissues via adenosine A2A receptor (A2AR) which is widely expressed on immune cells, inhibiting anti-tumor immune response accordingly ...
Jia LIU +6 more
doaj +1 more source
Adenosine and preeclampsia [PDF]
Molecular Aspects of Medicine, 2017 Adenosine is an endogenous nucleoside with pleiotropic effects in different physiological processes including circulation, renal blood flow, immune function, or glucose homeostasis. Changes in adenosine membrane transporters, adenosine receptors, and corresponding intracellular signalling network associate with development of pathologies of pregnancy ...
Fabián Pardo +12 more
openaire +6 more sources
PAP and NT5E inhibit nociceptive neurotransmission by rapidly hydrolyzing nucleotides to adenosine
Molecular Pain, 2011 Background Prostatic acid phosphatase (PAP) and ecto-5'-nucleotidase (NT5E, CD73) produce extracellular adenosine from the nucleotide AMP in spinal nociceptive (pain-sensing) circuits; however, it is currently unknown if these are the main ...
Vihko Pirkko +7 more
doaj +1 more source
Stability of Diluted Adenosine Solutions in Polyolefin Infusion Bags [PDF]
, 2013 Background Intravenous or intracoronary adenosine is used in the cardiac catherization lab to achieve maximal coronary blood flow and determine fractional flow reserve.
Almagambetova, Elise +3 more
core +2 more sources
The role of adenosine in preconditioning by brief pressure overload in rats
Journal of the Formosan Medical Association, 2015 Brief pressure overload of the left ventricle reduced myocardial infarct (MI) size in rabbits has been previously reported. Its effects in other species are not known. This study investigates effects of pressure overload and the role of adenosine in rats
Cheng-Hsiung Huang +4 more
doaj +1 more source
Frontiers in Neurology, 2019 Epilepsy is a neurological disorder characterized by a long term propensity to produce unprovoked seizures and by the associated comorbidities including neurological, cognitive, psychiatric, and impairment the quality of life.
Fan Chen +3 more
doaj +1 more source
Biosensor measurement of purine release from cerebellar cultures and slices [PDF]
, 2010 We have previously described an action-potential and Ca2+-dependent form of adenosine release in the molecular layer of cerebellar slices. The most likely source of the adenosine is the parallel fibres, the axons of granule cells. Using microelectrode
Dale, Nicholas +2 more
core +3 more sources
Stability of diluted adenosine solutions in polyvinyl chloride infusion bags [PDF]
, 2011 Purpose The stability of diluted adenosine solutions in polyvinyl chloride infusion bags was studied. Methods Adenosine 50-, 100-, and 220-μg/mL solutions were prepared in 50-mL polyvinyl chloride (PVC) infusion bags containing 0.9% sodium chloride ...
Bollinger, Jessica E. +3 more
core +2 more sources
Human Adenosine A2A Receptor: Molecular Mechanism of Ligand Binding and Activation
Frontiers in Pharmacology, 2017 Adenosine receptors (ARs) comprise the P1 class of purinergic receptors and belong to the largest family of integral membrane proteins in the human genome, the G protein-coupled receptors (GPCRs).
Byron Carpenter, Guillaume Lebon
doaj +1 more source
Frontiers in Pharmacology, 2021 Extracts of the tropical Cinderella plant Synedrella nodiflora are used traditionally to manage convulsive conditions in the West African sub-region.
Patrick Amoateng +8 more
doaj +1 more source