Results 181 to 190 of about 124,204 (359)

Reduction of postischemic brain damage and memory deficits following treatment with the selective adenosine A1 receptor agonist [PDF]

, 1996
Dag K.J.E. Von Lubitz, Mark P. Beenhakker, Rick C.S. Lin, Margaret F. Carter, Ian A. Paul, Norbert Bischofberger, Kenneth A. Jacobson   +6 more
openalex   +1 more source

Adaptations to hypoxia in the vertebrate retina

The Journal of Physiology, EarlyView.
Abstract figure legend Most animals, including mammals, are susceptible to the damaging effects of hypoxia or ischaemia, where the result is neuronal cell death in the brain. By contrast, some neurons of the mammalian retina are less sensitive to hypoxia. In both brain and retina, neurons may survive if first preconditioned with ischaemia.
Michael G. Jonz
wiley   +1 more source

Adenozin által okozott T limfocita diszfunkció szepszisben = The role of adenosine in septic T lymphocyte dysfunction [PDF]

, 2009
A projekt során in vitro Th1/Th2 polarizációs rendszer, Th1 és Th2 irányba differenciáltnak tekinthető hibridóma sejtek, illetve in vivo immunizálással nyert Th1 és Th2 sejtek felhasználásával, valamint A2A receptor specifikus agonista CGS21680, A2A ...
Haskó, György
core  

Targeting Immune Checkpoints: Basic Signaling Pathways and Clinical Translation in Cancer Therapeutics

MedComm – Oncology, Volume 4, Issue 3, September 2025.
Immune checkpoints in tumor immunotherapy. Ligand binding to the receptor inhibits immune cell function, promotes tumor cell immune escape, and suppresses the immune response. The pathways of action are VISTA‐IGSF11, TIM‐3‐Ceacam1, CD47‐SIRPα, CTLA‐4‐CD80/CD86, PD‐L1‐PD‐1, MHC‐1‐LILRB, and CD24 ‐ Siglec ‐10. There are also other immune checkpoints such
Han Sun, Dan Huang, Huiling Zhang, Mingyuan Dong, Simiao Wang, Man Sun, Jiayi Liu, Yiqi Wang, Xiaojie Qu, Xuefeng Li, Zhaogang Yang   +10 more
wiley   +1 more source

ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Adenosine Stimulates Glutamate Release From Astrocytes via A2a Adenosine Receptors

Journal of Pharmacological Sciences, 2004
Adenosine enhanced intracellular Ca2+ concentrations in astrocytes via A2a adenosine receptors involving protein kinase A (PKA) activation. The Ca2+ rise is inhibited by brefeldin A, an inhibitor of vesicular transport; but not by neomycin and U73122 ...
Tomoyuki Nishizaki
doaj  

Adenosine A_2A Receptors Shut Down Adenosine A₁ Receptor-Mediated Presynaptic Inhibition to Promote Implementation of Hippocampal Long-Term Potentiation. [PDF]

Biomolecules, 2023
Lopes CR, Gonçalves FQ, Olaio S, Tomé AR, Cunha RA, Lopes JP.   +5 more
europepmc   +1 more source

Effects of KW-3902, a Novel Adenosine A1-Receptor Antagonist, on Cephaloridine-Induced Acute Renal Failure in Rats

, 1994
Ken Nagashima, Hideaki Kusaka, Kiyoshi Sato, Akira Karasawa   +3 more
openalex   +1 more source

Chronic NMDA receptor stimulation: therapeutic implications of its effect on adenosine A1 receptors [PDF]

, 1995
Dag K.J.E. Von Lubitz, Jeongho Kim, Mark P. Beenhakker, Margaret F. Carter, Rick C.S. Lin, Yacov Meshulam, John W. Daly, Dan Shi, Liming Zhou, Kenneth A. Jacobson   +9 more
openalex   +1 more source

Adenosine A1 receptor antagonist rolofylline alleviates axonopathy caused by human Tau ΔK280

Proceedings of the National Academy of Sciences of the United States of America, 2016
Frank J A Dennissen, M. Anglada-Huguet, A. Sydow, E. Mandelkow, E. Mandelkow   +4 more
semanticscholar   +1 more source

Insights Into the Conformational Dynamics of the Cytoplasmic Domain of Metal‐Sensing Sensor Histidine Kinase ZraS

Proteins: Structure, Function, and Bioinformatics, Volume 93, Issue 9, Page 1465-1480, September 2025.
ABSTRACT ZraS is a metal sensor integral to ZraPSR, a two‐component signaling system found in enterobacters. It belongs to a family of bifunctional sensor histidine kinases (SHKs) and is speculated to sense zinc‐induced stress on the bacterial envelope.
Nilima Mahapatra, Pranjal Mahanta, Shubhant Pandey, Rudresh Acharya   +3 more
wiley   +1 more source