Results 1 to 10 of about 1,615,435 (305)
Pharmacology of the Adenosine A3 Receptor in the Vasculature and Essential Hypertension. [PDF]
PLoS ONE, 2016 BACKGROUND:Essential hypertension is considered to be a multifactorial disorder and its aetiology has yet to be clearly identified. As the adenosine receptors have a significant role in mediating vasodilation, alterations in their structures or ...
Ming-Fen Ho +2 more
doaj +1 more source
The role of muscarinic receptors in the beneficial effects of adenosine against myocardial reperfusion injury in rats. [PDF]
PLoS ONE, 2011 Adenosine, a catabolite of ATP, displays a wide variety of effects in the heart including regulation of cardiac response to myocardial ischemia and reperfusion injury.
Lei Sun +8 more
doaj +1 more source
Pharmaceuticals, 2021 The G protein-coupled adenosine A2B receptor is suggested to be involved in various pathological processes accompanied by increased levels of adenosine as found in inflammation, hypoxia, and cancer.
Marcel Lindemann +9 more
doaj +1 more source
Frontiers in Physiology, 2023 Background: The basolateral potassium channels play an important role in maintaining the membrane transport in the renal proximal tubules (PT) and adenosine receptors have been shown to regulate the trans-epithelial Na+ absorption in the PT.
Hao Liu +5 more
doaj +1 more source
Influence of adenosine receptor ligands on ketamine-induced anesthesia in mice
Current Issues in Pharmacy and Medical Sciences, 2012 The influence of adenosine receptor ligands on anesthetic activity of ketamine was studied in mice. Ketamine-induced anesthesia (100 mg/kg) was significantly increased by the higher doses of CPA (selective A1 adenosine receptor agonist) and NECA (A1 ...
Sylwia Fidecka, Marcin Mandryk
doaj +1 more source
Molecular Vibration-Activity Relationship in the Agonism of Adenosine Receptors [PDF]
Genomics & Informatics, 2013 The molecular vibration-activity relationship in the receptor-ligand interaction of adenosine receptors was investigated by structure similarity, molecular vibration, and hierarchical clustering in a dataset of 46 ligands of adenosine receptors.
Hyun Keun Chee, S. June Oh
doaj +1 more source
Adenosine-Related Mechanisms in Non-Adenosine Receptor Drugs
Cells, 2020 Many ligands directly target adenosine receptors (ARs). Here we review the effects of noncanonical AR drugs on adenosinergic signaling. Non-AR mechanisms include raising adenosine levels by inhibiting adenosine transport (e.g., ticagrelor, ethanol, and ...
Kenneth A. Jacobson, Marc L. Reitman
doaj +1 more source
The Role of Adenosine Receptor Agonists in Regulation of Hematopoiesis
Molecules, 2011 The review summarizes data evaluating the role of adenosine receptor signaling in murine hematopoietic functions. The studies carried out utilized either non-selective activation of adenosine receptors induced by elevation of extracellular adenosine or ...
Michal Hofer +3 more
doaj +1 more source
Journal of Pharmacological Sciences, 2005 The aim of the present study is to clarify the mechanism for the decrease in intraocular pressure by 2-alkynyladenosine derivatives in rabbits. The receptor binding analysis revealed that 2-(1-octyn-1-yl)adenosine (2-O-Ado) and 2-(6-cyano-1-hexyn-1-yl ...
Takashi Konno +5 more
doaj +1 more source
Natural Product Communications, 2022 Our previous study demonstrated that an extract of Cordyceps militaris (CM) derived from Samia Cynthia ricini inhibits testosterone-induced prostate hypertrophy in an animal model.
Kazuya Kusama +8 more
doaj +1 more source