Results 241 to 250 of about 127,904 (323)

Selatogrel: Potential to redefine timely anti‐platelet intervention

British Journal of Pharmacology, Volume 182, Issue 22, Page 5435-5452, November 2025.
Acute coronary syndrome (ACS) encompasses a number of heart diseases that cause a sudden decrease in coronary perfusion, precipitating cardiomyocyte necrosis or heightened risk thereof. This pathology is a major burden of cardiovascular disease.
Rudy N. Zalzal, Peter P. Salem, Ali H. Dakroub, Ali H. Eid   +3 more
wiley   +1 more source

Frameshift Variant in Novel Adenosine-A1-Receptor Homolog Associated With Bovine Spastic Syndrome/Late-Onset Bovine Spastic Paresis in Holstein Sires. [PDF]

Front Genet, 2020
Krull F, Hirschfeld M, Wemheuer WE, Brenig B.   +3 more
europepmc   +1 more source

Discovery of Highly Potent Adenosine A₁ Receptor Agonists: Targeting Positron Emission Tomography Probes. [PDF]

ACS Chem Neurosci, 2021
Guo M, Bakhoda A, Gao ZG, Ramsey JM, Li Y, O'Conor KA, Kelleher AC, Eisenberg SM, Kang Y, Yan X, Javdan C, Fowler JS, Rice KC, Hooker JM, Jacobson KA, Kim SW, Volkow ND.   +16 more
europepmc   +1 more source

Central activation of the A1 adenosine receptor in fed mice recapitulates only some of the attributes of daily torpor

, 2017
Maria A. Vicent, Ethan D. Borre, Steven J. Swoap   +2 more
openalex   +2 more sources

Characterization of Drug–Drug Interactions for Remdesivir, an Intravenous Antiviral for SARS‐CoV‐2, in Healthy Participants

Clinical and Translational Science, Volume 18, Issue 11, November 2025.
ABSTRACT Remdesivir is an intravenous antiviral approved worldwide for the treatment of COVID‐19 in adults and children. Remdesivir, as a prodrug inhibitor of RNA polymerase, undergoes intracellular activation to form the active metabolite along with 2 inactive circulating metabolites, GS‐704277 and GS‐441524. Based on drug–drug interaction (DDI) risks
Jack Chang, Aryun Kim, Rita Humeniuk, Naveed A. Shaik, Helen Winter, Chi‐Chi Peng, Deqing Xiao, Mazin Abdelghany, Joe Llewellyn, Santosh Davies, Kandace Golden, Shuguang Chen, Robert H. Hyland, Luzelena Caro   +13 more
wiley   +1 more source

Pharmacology of Adenosine A₁ Receptor Agonist in a Humanized Esterase Mouse Seizure Model Following Soman Intoxication. [PDF]

Neurotox Res
Shih TM, Munoz C, Acon-Chen C, Keith ZM.
europepmc   +1 more source

Zinc finger protein 91 loss induces cardiac hypertrophy through adenosine A1 receptor down-regulation under pressure overload status. [PDF]

J Cell Mol Med, 2020
Wu X, You W, Wu Z, Ye F, Chen S.
europepmc   +1 more source

Input-selective adenosine A₁ receptor-mediated synaptic depression of excitatory transmission in dorsal striatum. [PDF]

Sci Rep, 2021
Fritz BM, Yin F, Atwood BK.
europepmc   +1 more source

Functionalized congeners of adenosine: preparation of analogs with high affinity for A1-adenosine receptors

, 1985
Kenneth A. Jacobson, Kenneth L. Kirk, William L. Padgett, John W. Daly   +3 more
openalex   +2 more sources

Protection From Demyelination by the Novel Adenosine Dual A2A/A2B Receptor Antagonist P626 in EAE and Cultured Oligodendrocyte Precursor Cells

Journal of Cellular and Molecular Medicine, Volume 29, Issue 22, November 2025.
ABSTRACT Multiple sclerosis (MS) is a chronic inflammatory disease characterised by myelin and axonal loss. Lack of remyelination is primarily attributed to the failure of oligodendrocyte progenitor cells (OPCs) to differentiate into mature oligodendrocytes.
M. Morozzi, F. Cherchi, C. Sasia, L. Frulloni, G. Videtta, M. Venturini, D. Catarzi, F. Varano, S. Calenda, C. Ceni, G. Vagnoni, V. Colotta, E. Coppi, A. M. Pugliese, N. Galeotti   +14 more
wiley   +1 more source