Results 41 to 50 of about 1,574,376 (193)
On the basis of sex: male vs. female rat adenosine A1/A2A receptor affinity
BMC Research Notes, 2023 Objective To ensure reproducibility in biomedical research, the biological variable sex must be reported; yet a reason for using male (instead of female) rodents is seldom given.
Helena D. Janse van Rensburg +2 more
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The role of the large conductance Ca2+-activated K+ channel in adenosine receptor-mediated cytoprotection [PDF]
, 2009 The rat embryonic cardiomyoblast-derived H9c2 cell line is increasingly used for studies into cardioprotection, as these cells display similar properties to primary cardiomyocytes.
Fretwell, Laurice V, Fretwell, LV
core
Frontiers in Pharmacology, 2016 Both adenosine A1 receptor and cGMP inhibit synaptic transmission at the hippocampus and recently it was found that A1 receptor increased cGMP levels in hippocampus, but the role of cGMP on A1 receptor-mediated inhibition of synaptic transmission remains
Isa ePinto +5 more
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The dynamics of single spike-evoked adenosine release in the cerebellum [PDF]
, 2011 The purine adenosine is a potent neuromodulator in the brain, with roles in a number of diverse physiological and pathological processes. Modulators such as adenosine are difficult to study as once released they have a diffuse action (which can affect ...
Boris P. Klyuch +7 more
core +1 more source
Regulación de receptores de neurotransmisores y neuromoduladores por proteínas estructurales [PDF]
, 2003 [cat] Los receptores acoplados a proteína G o de siete dominios transmembrana (GPCRs o 7TMR) constituyen la mayor superfamilia de receptores de membrana involucrados en la transducción de una señal extracelular al interior de la célula.
Burgueño Hurtado, Javier
core +6 more sources
Neural Regeneration Research, 2017 The activation of adenosine A1 receptors is important for protecting against ischemic brain injury and pretreatment with electroacupuncture has been shown to mitigate ischemic brain insult.
Qin-xue Dai +7 more
doaj +1 more source
Anticonvulsant activity of B2, an adenosine analog, on chemical convulsant-induced seizures. [PDF]
PLoS ONE, 2013 Epilepsy is a chronic neurological disorder characterized by recurrent seizures. However, approximately one-third of epilepsy patients still suffer from uncontrolled seizures. Effective treatments for epilepsy are yet to be developed. N (6)-(3-methoxyl-4-
Min Li +4 more
doaj +1 more source
Central adenosinergic system and its clinical importance
Psychiatry and Clinical Psychopharmacology, 2021 Adenosine is a neuromodulator widely distributed throughout the body. Since it is continuously synthesized, it can be concluded that there is a basal adenosinergic tonus, which has inhibitory effects in general.
Hakan Kayır, I. Tayfun Uzbay
doaj
Molecules, 2012 This study was undertaken in order to investigate the effect of chronic treatment with 5′-chloro-5′-deoxy-(±)-ENBA, a potent and highly selective agonist of human adenosine A1 receptor, on thermal hyperalgesia and mechanical ...
Livio Luongo +10 more
doaj +1 more source
Anti-inflammatory preconditioning by agonists of adenosine A1 receptor. [PDF]
PLoS ONE, 2008 BackgroundAdenosine levels rise during inflammation and modulate inflammatory responses by engaging with four different G protein-coupled receptors. It is suggested that adenosine exhibits pro-inflammatory effects through its A(1) receptor (A(1)R), and ...
Sigal Nakav +7 more
doaj +1 more source