Results 61 to 70 of about 1,574,376 (193)

A1 adenosine receptor evoked Ca2+ signals in astrocytes

Current Directions in Biomedical Engineering
In addition to neurons, glial cells make up the nervous system. These glial cells are divided into macroglial cells - including astrocytes - and microglial cells.
Kienleitner Filip, Lenk Kerstin
doaj   +1 more source

NEW INSIGHTS AND POSSIBLE THERAPEUTIC IMPLICATIONS OF ADENOSINE ANALOGS AND PULSED ELECTROMAGNETIC FIELDS (PEMFs) IN OSTEOARTICULAR PATHOLOGIES [PDF]

, 2009
Objective: The aim of this study was to characterize adenosine receptors in synovial fibroblasts (SFs) and to investigate the potential link between adenosine pathway and pulsed electromagnetic fields (PEMFs).
Masieri, Federica Francesca
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A depletable pool of adenosine in area CA1 of the rat hippocampus [PDF]

, 2001
Adenosine plays a major modulatory and neuroprotective role in the mammalian CNS. During cerebral metabolic stress, such as hypoxia or ischemia, the increase in extracellular adenosine inhibits excitatory synaptic transmission onto vulnerable neurons via
Darren Caldwell, Caldwell, Darren, Feruza Nuritova, Bruno G. Frenguelli, Dale, Nicholas, Pearson, Tim, Nuritova, Feruza, Frenguelli, Bruno G., Tim Pearson, Nicholas Dale   +9 more
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Reducing Extracellular Ca2+ Induces Adenosine Release via Equilibrative Nucleoside Transporters to Provide Negative Feedback Control of Activity in the Hippocampus

Frontiers in Neural Circuits, 2017
Neural circuit activity increases the release of the purine neuromodulator adenosine into the extracellular space leading to A1 receptor activation and negative feedback via membrane hyperpolarization and inhibition of transmitter release.
Rebecca Diez, Magnus J. E. Richardson, Mark J. Wall   +2 more
doaj   +1 more source

Atividade antinociceptiva da inosina em camundongos: participação dos receptores A1 e A2A [PDF]

, 2008
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaA inosina, um nucleosídeo endógeno, e o primeiro metabolito da adenosina, e e sintetizada atraves da adenosina pela ...
Nascimento, Francisney Pinto do
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Protective effect of Adenosine A1 receptor and ascorbic acid on hippocampal neuronal density and memory disorder in ischemia reperfusion induced Rats

مجله دانشگاه علوم پزشکی گرگان, 2012
Background and Objective: Brain ischemia is one of the most important factor of morbidity and mortality and leaving many people with mental and physical disabilities.
Zamani M (MSc), Rasooli H (PhD), Mehdizadeh M (PhD), Nobakht M (PhD), Zamani F (BSc), Soleimani M (PhD)   +5 more
doaj  

ALTERED EXPRESSION AND FUNCTIONALITY OF A2A ADENOSINE RECEPTORS IN HUNTINGTON’S DISEASE AND OTHER POLYGLUTAMINE DISORDERS [PDF]

, 2009
Several studies have suggested the possible involvement of A2A adenosine receptors in the pathogenesis of neuronal disorders, including Huntington’s disease.
Vincenzi, Fabrizio
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The Effects of the Adenosine Receptor Antagonists on the Reverse of Cardiovascular Toxic Effects Induced by Citalopram In-Vivo Rat Model of Poisoning

Balkan Medical Journal, 2015
Background: Citalopram is a selective serotonin reuptake inhibitor that requires routine cardiac monitoring to prevent a toxic dose. Prolongation of the QT interval has been observed in acute citalopram poisoning.
Müjgan Büyükdeligöz, Nil Hocaoğlu, Kubilay Oransay, Yeşim Tunçok, Şule Kalkan   +4 more
doaj   +1 more source

Impairment of adenosine signaling disrupts early embryo development: unveiling the underlying mechanisms

Frontiers in Pharmacology
Purinergic signaling has been implicated in many biological functions, including development. In this study, we investigate the functions of extracellular adenosine and adenosine receptors using a mouse embryonic stem cell (ESC) line and morula stages ...
Talita Glaser, Patrícia Martins, Renata Beco, Carolina Adriane Bento, Angelica R. Cappellari, Sophia La Banca Oliveira, Christian Albert Merkel, Vanessa Fernandes Arnaud-Sampaio, Claudiana Lameu, Ana Maria Battastini, Henning Ulrich   +10 more
doaj   +1 more source

Models for the PET quantitative imaging of the adenosine receptor radioligand [11C] SCH442416 in humans [PDF]

, 2010
Positron Emission Tomography is an important imaging technique, that enables regional function to be assayed in a fully quantitative and noninvasive manner. It is based on the use of radioactive tracers: [11C]SCH442416, which is the compound of interest
Boscolo Galazzo, Ilaria
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