Results 51 to 60 of about 1,574,376 (193)

THE A3 ADENOSINE RECEPTOR: A LINK BETWEEN INFLAMMATION AND CANCER. [PDF]

, 2010
Adenosine is an endogenous and ubiquitous nucleoside that exerts many biological functions through interaction with 4 distinct subtypes of G protein-coupled receptors divided into A1, A2A, A2B, and A3.
Sacchetto, Valeria
core  

Targeting Adenosine A2b Receptor Promotes Penile Rehabilitation of Refractory Erectile Dysfunction

Advanced Science
The mechanisms of adenosine and specific adenosine receptor subtypes in promoting penile rehabilitation remain unclear. Single‐cell RNA sequencing of human corpus cavernosum,  adenosine deaminase (ADA) and adenosine receptors knock‐out mice (ADA−/−, A1−/−
Yang Xiong, Feng Qin, Shanzun Wei, Xingliang Yang, Jun Li, Changjing Wu, Fuxun Zhang, Jiuhong Yuan   +7 more
doaj   +1 more source

Adenosine Receptor Agonists Modulate Visceral Hyperalgesia in the Rat

Gut and Liver, 2008
Background/Aims: Adenosine is an endogenous modulator of nociception. Its role in visceral nociception, particularly in visceral hyperalgesia, has not been studied.
doaj   +1 more source

Cross-communication between Gi and Gs in a G-protein-coupled receptor heterotetramer guided by a receptor C-terminal domain

BMC Biology, 2018
Background G-protein-coupled receptor (GPCR) heteromeric complexes have distinct properties from homomeric GPCRs, giving rise to new receptor functionalities.
Gemma Navarro, Arnau Cordomí, Marc Brugarolas, Estefanía Moreno, David Aguinaga, Laura Pérez-Benito, Sergi Ferre, Antoni Cortés, Vicent Casadó, Josefa Mallol, Enric I. Canela, Carme Lluís, Leonardo Pardo, Peter J. McCormick, Rafael Franco   +14 more
doaj   +1 more source

Synergistic Effects of Adenosine A2A Antagonist and L-DOPA on Rotational Behaviors in 6-Hydroxydopamine-Induced Hemi-Parkinsonian Mouse Model

Journal of Pharmacological Sciences, 2007
In this study, we examined the combination effects of L-DOPA and adenosine receptor antagonists on rotational behaviors in a hemi-Parkinsonian mouse model induced by unilateral 6-hydroxydopamine (6-OHDA) injection. The adenosine A2A antagonist SCH-58261,
Takahiro Matsuya, Kazuhiro Takuma, Kosuke Sato, Makoto Asai, Yoshihiro Murakami, Sosuke Miyoshi, Akihiro Noda, Taku Nagai, Hiroyuki Mizoguchi, Shintaro Nishimura, Kiyofumi Yamada   +10 more
doaj   +1 more source

Influência do sistema adenosinérgico nas respostas comportamentais de ansiedade, tolerância e reforço positivo induzidas pelo etanol em camundongos [PDF]

, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.Um número crescente de evidências tem apontado para o neuromodulador adenosina como um importante mediador de várias
Batista, Luciano da Conceição
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Electroacupuncture Pretreatment Prevents Cognitive Impairment Induced by Cerebral Ischemia–Reperfusion via Adenosine A1 Receptors in Rats

Frontiers in Aging Neuroscience, 2021
A previous study has demonstrated that pretreatment with electroacupuncture (EA) induces rapid tolerance to focal cerebral ischemia. In the present study, we investigated whether adenosine receptor 1 (A1 R) is involved in EA pretreatment-induced ...
Yiyi Shi, Qinxue Dai, Binbin Ji, Luping Huang, Xiuxiu Zhuang, Yunchang Mo, Junlu Wang   +6 more
doaj   +1 more source

Interação entre os sistemas adenosinérgico e endocanabinóide, através dos receptores A1 e CB1, no controle da memória espacial [PDF]

, 2011
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaOs sistemas endocanabinóide e adenosinérgico, através dos receptores A1 e CB1, compartilham uma série de características ...
Assini, Fabrício Luiz
core  

In vivo co-ordinated interactions between inhibitory systems to control glutamate mediated hippocampal excitability. [PDF]

, 2013
We present an overview of the long-term adaptation of hippocampal neurotransmission to cholinergic and GABAergic deafferentation caused by excitotoxic lesion of the medial septum.
Rodríguez Allué, Manuel José, Robledo, Patricia, Mahy Gehenne, Josette Nicole, Andrade, Carmen   +3 more
core   +1 more source

An Allosteric Modulator of the Adenosine A1 Receptor Improves Cardiac Function Following Ischaemia in Murine Isolated Hearts

Pharmaceuticals, 2013
The effect of an allosteric modulator of the adenosine A1 receptors was investigated using an ischaemia-reperfusion protocol in murine isolated hearts. Isolated hearts were perfused with Kreb-Henseleit solution gassed with carbogen gas (95% O2 and 5% CO2)
Roselyn B. Rose'Meyer, Shane M. Devine, Peter J. Scammells, Paul J. White, Anna Butcher   +4 more
doaj   +1 more source