Results 121 to 130 of about 215,850 (301)
Background & Objective: Adenosine deaminase is an enzyme which catalyses adenosine to Inosine. The determination of adenosine deaminase in body fluids is important for the diagnosis of tuberculosis.
Hamid Reza Joshaghani+3 more
doaj
Tissue-characteristic forms of adenosine deaminase [PDF]
Newton Ressler
openalex +1 more source
ADAR1 mRNA quantification for predicting HSIL in persons with HIV and abnormal anal cytology
What's new? This study introduces ADAR1 mRNA quantification as a promising biomarker for improving high‐grade squamous intraepithelial lesion (HSIL) prediction in HIV‐positive individuals with abnormal anal cytology. With 92% specificity, it reduces unnecessary high‐resolution anoscopies (HRA) by 77%, offering a more efficient and targeted screening ...
Melissa Bello‐Perez+15 more
wiley +1 more source
Adenosine deaminase acting on RNA 1 (ADAR1) edits adenosine to inosine. Here the authors, using parallel analysis of RNA secondary structure sequencing, provide evidence that ADAR1 induces sequence-context-dependent RNA secondary structures changes ...
Oz Solomon+16 more
doaj +1 more source
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu+7 more
wiley +1 more source
Effect of Adenosine Deaminase upon the Antiviral Activity In Vitro of Adenine Arabinoside for Vaccinia Virus [PDF]
James D. Connor+4 more
openalex +1 more source
Engineered Cas12j‐8 is a Versatile Platform for Multiplexed Genome Modulation in Mammalian Cells
Engineered through structure‐guided protein engineering, enCas12j‐8 significantly enhances the editing efficiency of compact Cas12j‐8 while maintaining high specificity. It enables efficient multiplexed genome editing and base editing using a single crRNA array, demonstrating broad applicability and therapeutic potential in genome engineering ...
Ru Meng+14 more
wiley +1 more source
Purification and crystallization of adenosine deaminase in Pseudomonas iodinum IFO 3558 [PDF]
Takuo Sakai, Hong-Ki Jun
openalex +1 more source
A Case of Refractory Nephrotic Syndrome Complicated With Tuberculous Pleurisy and Literature Review
ABSTRACT Nephrotic syndrome(NS) can be classified into steroid‐sensitive nephrotic syndrome (SSNS) and steroid‐resistant nephrotic syndrome (SRNS). Rifampicin is potentially leading to treatment resistance in NS. Here we report a case of SRNS secondary to rifampicin‐induced drug interactions during antituberculosis therapy.
Jiang‐min Wan+5 more
wiley +1 more source