Results 131 to 140 of about 238,585 (333)

Mutant adenosine deaminase 2 in a polyarteritis nodosa vasculopathy.

New England Journal of Medicine, 2014
BACKGROUND Polyarteritis nodosa is a systemic necrotizing vasculitis with a pathogenesis that is poorly understood. We identified six families with multiple cases of systemic and cutaneous polyarteritis nodosa, consistent with autosomal recessive ...
Paulina Navon Elkan, S. Pierce, R. Segel, T. Walsh, J. Barash, S. Padeh, A. Zlotogorski, Y. Berkun, Joseph J Press, M. Mukamel, I. Voth, P. Hashkes, L. Harel, V. Hoffer, E. Ling, F. Yalçınkaya, O. Kasapcopur, Ming K. Lee, R. Klevit, P. Renbaum, A. Weinberg-Shukron, E. Şener, B. Schormair, S. Zeligson, D. Marek‐Yagel, T. Strom, M. Shohat, A. Singer, A. Rubinow, E. Pras, J. Winkelmann, M. Tekin, Y. Anikster, M. King, E. Levy-Lahad   +34 more
semanticscholar   +1 more source

AMPK Regulation of Mouse Oocyte Meiotic Resumption in Vitro [PDF]

, 2006
We have previously shown that the adenosine analog 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR), an activator of AMP-activated protein kinase (AMPK), stimulates an increase in AMPK activity and induces meiotic resumption in mouse oocytes ...
Chang, Aimee S., Chen, Jing, Chi, Maggie M., Downs, Stephen M., Hardie, D. Grahame, Hudson, Emma R., Moley, Kelle H.   +6 more
core   +2 more sources

Frenkel Exciton Model of Ultrafast Excited State Dynamics in AT DNA Double Helices [PDF]

J. Photochem. and Photobiol. A 190, 328-334 (2007), 2006
Recent ultrafast experiments have implicated intrachain base-stacking rather than base-pairing as the crucial factor in determining the fate and transport of photoexcited species in DNA chains. An important issue that has emerged concerns whether or not a Frenkel excitons is sufficient one needs charge-transfer states to fully account for the dynamics.
arxiv  

Implications for soluble iron accumulation, oxidative stress, and glial glutamate release in motor neuron death associated with sporadic amyotrophic lateral sclerosis

Neuropathology, EarlyView.
Oxidative stress in sporadic amyotrophic lateral sclerosis (ALS) has been evidenced by accumulation of oxidatively modified products of nucleic acids, lipids, sugars, and proteins in the motor neuron system of brains and spinal cords obtained at autopsy from the patients.
Noriyuki Shibata, Ikuko Kataoka, Yukinori Okamura, Kumiko Murakami, Yoichiro Kato, Tomoko Yamamoto, Kenta Masui   +6 more
wiley   +1 more source

Adenosine Deaminase

Definitions, 2020
P. Sears
semanticscholar   +2 more sources

Coulomb Interaction as the Source of Muscle Force [PDF]

arXiv, 2007
Myosin motor is the machine, which performs mechanical work in the course of adenosine triphosphate molecule hydrolysis and myosin head conformations accompanying this process. For displacement of individual fragments of large molecule relative to each other to arise and work to be performed, force must be born inside protein.
arxiv  

An RNA editor, adenosine deaminase acting on double-stranded RNA (ADAR1).

Journal of Interferon and Cytokine Research, 2014
Adenosine deaminase acting on RNA1 (ADAR1) catalyzes the C6 deamination of adenosine (A) to produce inosine (I) in regions of RNA with double-stranded (ds) character. This process is known as A-to-I RNA editing. Alternative promoters drive the expression
C. George, Lijo John, C. E. Samuel
semanticscholar   +1 more source

Hematopoietic Stem Cell Transplantation Outcomes in Diamond–Blackfan Anemia Patients Based on Myeloablative Conditioning Regimen With or Without Total Body Irradiation: A Systematic Review and Meta‐Analysis

eJHaem, Volume 6, Issue 3, June 2025.
ABSTRACT Diamond–Blackfan anemia (DBA) is a rare, congenital bone marrow failure syndrome characterized by hypoplastic anemia. Earliest descriptions of this disease date back to 1936, and since then, a plethora of treatment strategies have been used to control or treat the disease.
Parsa Fathi, Leila Jafari, Afshin Fathi, Ayat Ahmadi, Yalda Karamlou, Maryam Behfar, Amir Ali Hamidieh   +6 more
wiley   +1 more source

Disinhibition of hippocampal CA3 neurons induced by suppression of an adenosine A1 receptor-mediated inhibitory tonus: Pre- and postsynaptic components [PDF]

, 1993
Intracellular recordings were performed on hippocampal CA3 neuronsin vitro to investigate the inhibitory tonus generated by endogenously produced adenosine in this brain region.
Alzheimer, Alzheimer, Alzheimer, Alzheimer, Andreasen, Arai, Ault, Ault, B. Sutor, Bauer, Beavo, Beavo, Ben-Ari, Bruns, Bruns, C. Alzheimer, Chamberlin, Daly, Dragunow, Dragunow, Dunwiddie, Dunwiddie, Dunwiddie, Fredholm, G. Ten Bruggencate, Gerber, Greene, Greene, Haas, Hablitz, Hablitz, Jackisch, Johnston, Linden, Linden, Llinás, Lohse, Madison, Malenka, Meghji, Miles, Moraidis, Nicholson, Pockett, Prestwich, Prince, Scholz, Schubert, Schubert, Smellie, Smellie, Smith, Snyder, Snyder, Sutor, Tanaka, Thompson, Thompson, Van Calker, Williams, Zetterström   +60 more
core   +1 more source

Atypical phenotype of an old disease or typical phenotype of a new disease: deficiency of adenosine deaminase 2

The Turkish Journal of Pediatrics, 2019
Deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessive autoinflammatory disorder caused by mutations in CECR1 (cat eye syndrome chromosome region, canditate 1) gene, which encodes the enzyme adenosine deaminase 2 necessary for endothelial
Mustafa Çakan, Nuray Aktay-Ayaz, Şerife Gül Karadağ, Eda Tahir-Turanlı, Kelsey Stafstrom, Wayne Bainter, Raif S Geha, Janet Chou   +7 more
doaj   +1 more source