Results 51 to 60 of about 238,585 (333)
The Diagnostic Efficacy of Adenosine Deaminase in Tubercular Effusion
Oman Medical Journal, 2013 Objective: This study aims to evaluate the diagnostic efficacy of adenosine deaminase in tubercular effusions.Methods: This study was conducted at the Department of General Medicine and Cardiovascular and Thoracic Surgery, SKIMS, for a period of two ...
Mohd Arif Kelam +6 more
doaj +1 more source
Kissing loop interaction in adenine riboswitch: insights from umbrella sampling simulations [PDF]
BMC Bioinformatics 2015, 16(Suppl 9):S6, 2015 Riboswitches are cis-acting regulatory RNA elements prevalently located in the leader sequences of bacterial mRNA. An adenine sensing riboswitch cis-regulates adeninosine deaminase gene (add) in Vibrio vulnificus. The structural mechanism regulating its conformational changes upon ligand binding mostly remains to be elucidated.
arxiv +1 more source
Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis
Brain : a journal of neurology, 2019 Using metabolic screening, Allen et al. identify an adenosine to inosine deamination defect in astrocytes from ALS patients. This defect is the result of reduced expression of adenosine deaminase, leading to increased susceptibility to adenosine-mediated
Scott P. Allen +22 more
semanticscholar +1 more source
DNA editing in DNA/RNA hybrids by adenosine deaminases that act on RNA. [PDF]
, 2017 Adenosine deaminases that act on RNA (ADARs) carry out adenosine (A) to inosine (I) editing reactions with a known requirement for duplex RNA. Here, we show that ADARs also react with DNA/RNA hybrid duplexes.
Beal, Peter A +2 more
core +1 more source
The Scientific World Journal, 2012 L-arginine is conditionally essetcial amino acid, required for normal cell growth, protein synthesis, ammonia detoxification, tissue growth and general performance, proposed in the treatment of men sterility and prevention of male impotence.
G. Kocic +8 more
doaj +1 more source
Nature Communications, 2018 Systematic exploration of cancer cell vulnerabilities can inform the development of novel cancer therapeutics. Here, through analysis of genome-scale loss-of-function datasets, we identify adenosine deaminase acting on RNA (ADAR or ADAR1) as an essential
Hugh S. Gannon +15 more
semanticscholar +1 more source
New insights into the biological role of mammalian ADARs; the RNA editing proteins [PDF]
, 2015 The ADAR proteins deaminate adenosine to inosine in double-stranded RNA which is one of the most abundant modifications present in mammalian RNA.
Arieti, Fabiana +4 more
core +2 more sources
A role for adenosine deaminase in Drosophila larval development. [PDF]
PLoS Biology, 2005 Adenosine deaminase (ADA) is an enzyme present in all organisms that catalyzes the irreversible deamination of adenosine and deoxyadenosine to inosine and deoxyinosine.
Tomas Dolezal +3 more
doaj +2 more sources
Jornal Brasileiro de Pneumologia, 2004 INTRODUÇÃO: O diagnóstico da tuberculose pleural permanece um desafio, pois a sensibilidade dos testes tradicionais é baixa. O exame histopatológico da pleura é o método mais preciso, com até 80% de sensibilidade.
Morrys Casagrande Kaisemann +3 more
doaj +1 more source
The Kinetic Study of Adenosine Deaminase Activity in Renal Failure Patients [PDF]
Kirkuk Journal of Science, 2011 Serum adenosine deaminase levels was measured in patients with acute renal failure and compare them with the results of healthy individuals. Serum adenosine deaminase levels were found to be significantly higher in patient with acute renal failure than ...
Lutfia M. Hassan, Parween A. Ismahail
doaj +1 more source