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adenosine deaminase deficiency
Citation: 'adenosine deaminase deficiency' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12847 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual ...
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Effect of endogenous adenosine augmentation on ischemia and reperfusion injury to the liver [PDF]
Ishizaki, N +8 more
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Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage [PDF]
Doctor, Allan +2 more
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Adenosine deaminase inhibition
International Journal of Biological Macromolecules, 2019Adenosine deaminase is a critical enzyme in purine metabolism that regulates intra and extracellular adenosine concentrations by converting it to inosine. Adenosine is an important purine that regulates numerous physiological functions by interacting with its receptors.
Bagheri, S., Saboury, A.A., Haertle, T.
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Adenosine Deaminase Deficiency
Hospital Practice, 1987Inherited deficiency of the purine salvage enzyme adenosine deaminase (ADA) is responsible for approximately half the cases of autosomal recessive Severe Combined Immunodeficiency (SCID). Deficiency of ADA can also result in a much later-onset, milder immunodeficiency, while lesser degrees of enzyme deficiency can result in either late-onset ...
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Adenosine deaminase inhibitors: Differential effects on multiple forms of adenosine deaminase
Biochemical and Biophysical Research Communications, 1978Summary Three forms of calf intestine adenosine deaminase were resolved by gel filtrat in Sephacryl C-200 into species of 38,000 (E S ), 57,000 (E I ) and greater than 200,00 (E L ) daltons. The sensitivities of the three forms of adenosine deaminase to the adenosine deaminase inhibitors, 2′-deoxycoformycin (dCF) and erythro-9-(2-hydroxynonyl)adenine
J, Constine, R I, Glazer, D G, Johns
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Treatment of Adenosine Deaminase Deficiency with Polyethylene Glycol–Modified Adenosine Deaminase
New England Journal of Medicine, 1987We treated two children who had adenosine deaminase deficiency and severe combined immunodeficiency disease by injecting bovine adenosine deaminase modified by conjugation with polyethylene glycol. The modified enzyme was rapidly absorbed after intramuscular injection and had a half-life in plasma of 48 to 72 hours.
Michael S. Hershfield +10 more
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Methods in enzymology, 1977
Adenosine deaminase plays a key role in adenosine metabolism. This nueleoside has some important pharmacological and toxic effects. An adenosine deaminase deficiency observed in some cases of severe congenital immunodeficiency represents the first link between an immunological and enzymic defect.
Ronca G +2 more
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Adenosine deaminase plays a key role in adenosine metabolism. This nueleoside has some important pharmacological and toxic effects. An adenosine deaminase deficiency observed in some cases of severe congenital immunodeficiency represents the first link between an immunological and enzymic defect.
Ronca G +2 more
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