Impulse oscillometry identifies peripheral airway dysfunction in children with adenosine deaminase deficiency. [PDF]
, 2015 Adenosine deaminase-deficient severe combined immunodeficiency (ADA-SCID) is characterized by impaired T-, B- and NK-cell function. Affected children, in addition to early onset of infections, manifest non-immunologic symptoms including pulmonary ...
Candotti, Fabio +6 more
core +2 more sources
Journal of Biological Chemistry, 2019 Herbert “Herb” Tabor, who celebrated his 100th birthday this past year, served the Journal of Biological Chemistry as a member of the Editorial Board beginning in 1961, as an Associate Editor, and as Editor-in-Chief for 40 years, from 1971 until 2010 ...
C. E. Samuel
semanticscholar +1 more source
Ultraslow water-mediated transmembrane interactions regulate the activation of A$_{\text{2A}}$ adenosine receptor [PDF]
Biophys. J. (2016) vol. 111, 1180-1191, 2016 Water molecules inside G-protein coupled receptor have recently been spotlighted in a series of crystal structures. To decipher the dynamics and functional roles of internal waters in GPCR activity, we studied A$_{\text{2A}}$ adenosine receptor using $\mu$sec-molecular dynamics simulations.
arxiv +1 more source
Trypanosoma brucei methylthioadenosine phosphorylase protects the parasite from the antitrypanosomal effect of deoxyadenosine [PDF]
, 2016 Trypanosoma brucei causes African sleeping sickness for which no vaccine exists and available treatments are of limited use due to their high toxicity or lack of efficacy. T.
de Koning, Harry P. +4 more
core +1 more source
Adenosine deaminase production by an endophytic bacterium (Lysinibacillus sp.) from Avicennia marina [PDF]
, 2013 The present study was carried out with the following objectives: (1) to isolate the endophytic bacilli strains from the leaves of mangrove plant Avicennia marina, (2) to screen the potential strains for the production of adenosine deaminase, (3) to ...
Kandasamy Kathiresan +3 more
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The Iraqi Journal of Veterinary Medicine, 2000 The present investigation aimed to study the Adenosine Deaminase activity in induction Cytogentic and histopathological change in skin and eyes of sumicidine treated rats. The study Included. 1-Adenosine deaminase activity . 2-Total serum protein.
Bushra Ibrahim Al-Qaisi
doaj +1 more source
Effect of diabetes/hyperglycemia on the rat retinal adenosinergic system. [PDF]
PLoS ONE, 2013 The early stages of diabetic retinopathy (DR) are characterized by alterations similar to neurodegenerative and inflammatory conditions such as increased neural apoptosis, microglial cell activation and amplified production of pro-inflammatory cytokines.
Joana Vindeirinho +4 more
doaj +1 more source
Broadband terahertz time-domain spectroscopy and fast FMCW imaging: principle and applications [PDF]
, 2020 We report a broadband terahertz time-domain spectroscopy (THz-TDS) which enables twenty vibrational modes of adenosine nucleoside to be resolved in a wide frequency range of 1-20 THz. The observed spectroscopic features of adenosine are in good agreement with the published spectra obtained using Fourier Transform Infrared Spectroscopy (FTIR) and Raman ...
arxiv +1 more source
A new intrinsic thermal parameter for enzymes reveals true temperature optima [PDF]
, 2004 Two established thermal properties of enzymes are the Arrhenius activation energy and thermal stability. Arising from anomalies found in the variation of enzyme activity with temperature, a comparison has been made of experimental data for the activity ...
Daniel, Roy M. +4 more
core +2 more sources
Pleural adenosine deaminase estimation: A Potential marker to distinguish between tubercular and non-tubercular effusion [PDF]
Al Ameen Journal of Medical Sciences, 2018 Background: Tuberculosis is a common cause of pleural effusion in countries like India where it is highly endemic. The biochemical markers are more sensitive and reliable in the diagnosis of pleural tuberculosis.
Anil C. Byakod, M.S. Biradar
doaj