Results 111 to 120 of about 90,132 (350)

Salvage enzymes in nucleotide biosynthesis [PDF]

, 2007
Balanced pools of deoxyribonucleoside triphosphates (dNTPs), the building blocks of DNA, and ribonucleoside triphosphates (NTPs), the precursors of RNA, are crucial for a controlled cell proliferation.
Kosinska, Urszula
core  

Nucleotides: Structure and Properties [PDF]

, 2005
Nucleotides consist of a nitrogen-containing base, a five-carbon sugar, and one or more phosphate groups. Cells contain many types of nucleotides, which play a central role in a wide variety of cellular processes, including metabolic regulation and the ...
Bowater, RP
core   +1 more source

The effect of trimetazidine on cardiac haemodynamics and mitochondrial function in wild‐type transthyretin amyloidosis

ESC Heart Failure, EarlyView.
Abstract Aims Wild‐type transthyretin cardiac amyloidosis (ATTRwt) is a cardiomyopathy causing myocardial hypoperfusion and impaired cardiac mitochondrial function. Trimetazidine is an antianginal agent used in patients with stable angina pectoris, which improves cardiac contractility and mitochondrial function.
Bertil Thyrsted Ladefoged, Anders Lehmann Dahl Pedersen, Anne Mette Dybro, Tor Skibsted Clemmensen, Julian Gillmore, Steen Hvitfeldt Poulsen   +5 more
wiley   +1 more source

Advancements in left ventricular assist devices to prevent pump thrombosis and blood coagulopathy

Journal of Anatomy, Volume 242, Issue 1, Page 29-49, January 2023., 2023
Left ventricular assist device (LVAD)‐related blood coagulopathy: Pump thrombosis is one of the most severe adverse events caused by LVADs. The contact of blood with artificial materials of LVAD pumps and cannulas triggers the coagulation cascade. Abstract Mechanical circulatory support (MCS) devices, such as left ventricular assist devices (LVADs) are
Grainne Malone, Gerges Abdelsayed, Fianait Bligh, Fatma Al Qattan, Saifullah Syed, Prateepan Varatharajullu, Augustin Msellati, Daniela Mwipatayi, Maimoona Azhar, Andrew Malone, Saulat H. Fatimi, Claire Conway, Aamir Hameed   +12 more
wiley   +1 more source

ATP Hysteresis in Tripartite Synapses [PDF]

arXiv, 2009
Recent experimental studies strongly suggest the influence of glial purinergic transmission in the modulation of synaptic dynamics. By releasing adenosine triphosphate (ATP), which accumulates as adenosine, astrocytes tonically suppressed synaptic transmission. The delayed multi-step feedback of the glial adenosine with the neuron suggest the existence
arxiv  

Association of plasma metabolites and cardiac mitochondrial function with heart failure progression

ESC Heart Failure, EarlyView.
Abstract Aims Plasma metabolites are prognostic in heart failure with reduced ejection fraction (HFrEF), with citric acid cycle metabolites linked to ejection fraction (EF) changes. We investigated these mechanisms in a canine chronic HFrEF model. We tested associations between changes in plasma metabolites, left ventricular (LV) end‐diastolic volume ...
Vandana Revathi Venkateswaran, Ruicong She, Stephen J. Gardell, Jasmine A. Luzum, Ramesh Gupta, Kefei Zhang, L. Keoki Williams, Hani N. Sabbah, David E. Lanfear   +8 more
wiley   +1 more source

Direct Growth Graphene on Cu Nanoparticles by Chemical Vapor Deposition as Surface-Enhanced Raman Scattering Substrate for Label-Free Detection of Adenosine [PDF]

arXiv, 2015
We present a graphene/Cu nanoparticle hybrids (G/CuNPs) system as a surface-enhanced Raman scattering (SERS) substrate for adenosine detection. The Cu nanoparticles wrapped around a monolayer graphene shell were directly synthesized on flat quartz by chemical vapor deposition in a mixture of methane and hydrogen.
arxiv  

A Simple and Rapid Determination of ATP, ADP and AMP Concentrations in Pericarp Tissue of Litchi Fruit by High Performance Liquid Chromatography

Food Technology and Biotechnology, 2006
A simple and rapid method using high performance liquid chromatography (HPLC) was developed to determine levels of adenosine triphosphate (ATP), adenosine diphosphate (ADP) and adenosine monophosphate (AMP) in litchi fruit pericarp tissue.
Weibo Jiang, Yunbo Luo, Hai Liu, Yueming Jiang   +3 more
doaj  

Electron microscopic findings predict clinical outcomes in patients with non‐ischaemic cardiomyopathy

ESC Heart Failure, EarlyView.
Abstract Aims Electron microscopy reveals microstructural alterations in cardiomyocyte nuclei and myofilaments in non‐ischaemic cardiomyopathy (NICM), particularly in dilated cardiomyopathy (DCM). Nevertheless, the correlation between such observations and clinical outcomes, including prognosis and left ventricular reverse remodelling (LVRR), remains ...
Rie Higuchi, Shozo Konishi, Tomohito Ohtani, Fusako Sera, Misato Chimura, Machiko Kanzaki, Themistoklis Katsimichas, Masahiro Seo, Tetsuya Watanabe, Takahiro Okumura, Toyoaki Murohara, Hiroyuki Takahama, Atsushi Okada, Chisato Izumi, Masaru Hatano, Issei Komuro, Yoshihiko Ikeda, Yoshihiro Asano, Hatsue Ishibashi‐Ueda, Yasushi Sakata   +19 more
wiley   +1 more source

Computational Study of Molecular Mechanisms of Caffeine Actions [PDF]

arXiv, 2015
Caffeine (CAF) is one of the most widely and regularly consumed biologically active substances. We use computer simulation approach to the study of CAF activity by searching for its possible complexes with biopolymer fragments. The principal CAF target at physiologically important concentrations refers to adenosine receptors.
arxiv