Results 181 to 190 of about 105,286 (352)

Thiamine supplementation modulates oxidative stress by inhibiting hepatic adenosine diphosphate (ADP)-ribosylation in obese diabetic rats

open access: diamond, 2019
Yuka Kohda   +10 more
openalex   +2 more sources

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1617-1627, 15 March 2026.
What's new? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman   +15 more
wiley   +1 more source

Remote delivery of cancer genetic testing in veterans with metastatic prostate cancer: A Million Veteran Program pilot study

open access: yesCancer, Volume 132, Issue 3, 1 February 2026.
Abstract Background Germline pathogenic variants can inform targeted therapy for metastatic prostate cancer (mPC), and improve cancer early detection and risk reduction for family members. Guidelines recommend germline genetic testing be offered to all men with mPC, yet uptake of testing is only 10%–12%. Methods This prospective study enrolled veterans
Bruce Montgomery   +18 more
wiley   +1 more source

Acute Hypoxia Decreases Maximum Fat Oxidation Rate During Step Incremental Exercise Normalized to Respiratory Compensation Point

open access: yesEuropean Journal of Sport Science, Volume 26, Issue 2, February 2026.
ABSTRACT Whether fat oxidation (FATox) is altered during exercise in hypoxia remains equivocal due to differences in experimental protocols. Furthermore, to date no investigation has reported the effect of hypoxia on maximal fat oxidation rate (MFO).
Youmna Elsayed Hassanein   +3 more
wiley   +1 more source

Risk of Stroke in Patients With High On-Clopidogrel Platelet Reactivity to Adenosine Diphosphate After Percutaneous Coronary Intervention [PDF]

open access: bronze, 2014
Nevio Taglieri   +10 more
openalex   +1 more source

Home - About - Disclaimer - Privacy