Results 181 to 190 of about 105,286 (352)
What's new? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman +15 more
wiley +1 more source
Reduced adenosine diphosphate sensitivity in skeletal muscle mitochondria increases reactive oxygen species production in mouse models of aging and oxidative stress but not denervation. [PDF]
Pharaoh G +4 more
europepmc +1 more source
Abstract Background Germline pathogenic variants can inform targeted therapy for metastatic prostate cancer (mPC), and improve cancer early detection and risk reduction for family members. Guidelines recommend germline genetic testing be offered to all men with mPC, yet uptake of testing is only 10%–12%. Methods This prospective study enrolled veterans
Bruce Montgomery +18 more
wiley +1 more source
Starch Granule-bound Adenosine Diphosphate Glucose-Starch Glucosyltransferases of Maize Seeds
Tadami Akatsuka, Oliver E. Nelson
openalex +1 more source
Properties of Purified Calf Thymus Poly(Adenosine Diphosphate Ribose) Polymerase. Comparison of the DNA-Independent and the DNA-Dependent Enzyme [PDF]
Claude Niedergang +2 more
openalex +1 more source
ABSTRACT Whether fat oxidation (FATox) is altered during exercise in hypoxia remains equivocal due to differences in experimental protocols. Furthermore, to date no investigation has reported the effect of hypoxia on maximal fat oxidation rate (MFO).
Youmna Elsayed Hassanein +3 more
wiley +1 more source
Risk of Stroke in Patients With High On-Clopidogrel Platelet Reactivity to Adenosine Diphosphate After Percutaneous Coronary Intervention [PDF]
Nevio Taglieri +10 more
openalex +1 more source

