Anti-platelet therapy: ADP receptor antagonists. [PDF]
, 2011 The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis.
Heptinstall, S, Wijeyeratne, YD
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The membrane bound N-terminal domain of human adenosine diphosphate ribosylation factor-1 (ARF1) [PDF]
, 2003 The small G protein adenosine diphosphate ribosylation factor-1 (ARF1) is activated by cell membrane binding of a self-folding N-terminal domain. We present a model of the human ARF1 N-terminal peptide in planar lipid bilayers, determined from neutron ...
Amor +22 more
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ADMINISTRATION OF FRUCTOSE 1,6-DIPHOSPHATE DURING EARLY REPERFUSION SIGNIFICANTLY IMPROVES RECOVERY OF CONTRACTILE FUNCTION IN THE POSTISCHEMIC HEART [PDF]
, 1998 Objectives: Fructose-1,6-diphosphate is a glycolytic intermediate that has been shown experimentally to cross the cell membrane and lead to increased glycolytic flux.
Cao-Danh, Hung +7 more
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Ischemic preconditioning attenuates portal venous plasma concentrations of purines following warm liver ischemia in man [PDF]
, 2005 Background/Aims: Degradation of adenine nucleotides to adenosine has been suggested to play a critical role in ischemic preconditioning (IPC). Thus, we questioned in patients undergoing partial hepatectomy whether (i) IPC will increase plasma purine ...
Chouker, A. +9 more
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Phosphoproteins and protein-kinase activity in isolated envelopes of pea (Pisum sativum L.) chloroplasts [PDF]
, 1985 A protein kinase was found in envelope membranes of purified pea (Pisum sativum L.) chloroplasts. Separation of the two envelope membranes showed that most of the enzyme activity was localized in the outer envelope.
D.G. Robinson +17 more
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Dynamics of Microtubule Growth and Catastrophe [PDF]
Phys. Rev. E 76, 041907 (2007), 2007 We investigate a simple model of microtubule dynamics in which a microtubule evolves by: (i) attachment of guanosine triphosphate (GTP) to its end at rate lambda, (ii) GTP converting irreversibly to guanosine diphosphate (GDP) at rate 1, and (iii) detachment of GDP from the end of a microtubule at rate mu.
arxiv +1 more source
Role of APD-ribosylation in bone health and disease [PDF]
, 2019 The transfer of adenosine diphosphate (ADP)-ribose unit(s) from nicotinamide adenine dinucleotide ...
Mbalaviele, Gabriel, Wang, Chun
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Dynamics of Microtubule Instabilities [PDF]
J. Stat. Mech. (2007) L05004, 2007 We investigate the dynamics of an idealized model of microtubule growth that evolves by: (i) attachment of guanosine triphosphate (GTP) at rate lambda, (ii) conversion of GTP to guanosine diphosphate (GDP) at rate 1, and (iii) detachment of GDP at rate mu. As a function of these rates, a microtubule can grow steadily or its length can fluctuate wildly.
arxiv +1 more source
Interlinked GTPase cascades provide a motif for both robust switches and oscillators [PDF]
J. R. Soc. Interface 16, 20190198 (2019), 2019 GTPases regulate a wide range of cellular processes, such as intracellular vesicular transport, signal transduction, and protein translation. These hydrolase enzymes operate as biochemical switches by toggling between an active guanosine triphosphate (GTP)-bound state and an inactive guanosine diphosphate (GDP)-bound state.
arxiv +1 more source
Enzymatic regeneration of adenosine triphosphate cofactor [PDF]
, 1974 Regenerating adenosine triphosphate (ATP) from adenosine diphosphate (ADP) by enzymatic process which utilizes carbamyl phosphate as phosphoryl donor is technique used to regenerate expensive cofactors.
Marshall, D. L.
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