Results 21 to 30 of about 89,334 (262)

Clinical Implications of “Tailored” Antiplatelet Therapy in Patients With Chronic Total Occlusion

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Clopidogrel nonresponsiveness is a prognostic marker after percutaneous coronary intervention. Prasugrel and ticagrelor provide a better platelet inhibition and represent the first‐line antiplatelet treatment in acute coronary syndrome.
Maria Grazia De Gregorio, Rossella Marcucci, Angela Migliorini, Anna Maria Gori, Betti Giusti, Ruben Vergara, Rita Paniccia, Nazario Carrabba, Niccolò Marchionni, Renato Valenti   +9 more
doaj   +1 more source

Role of APD-ribosylation in bone health and disease [PDF]

, 2019
The transfer of adenosine diphosphate (ADP)-ribose unit(s) from nicotinamide adenine dinucleotide ...
Mbalaviele, Gabriel, Wang, Chun
core   +2 more sources

Inhibition of Gastric Erosion Formations in Rats by Adenosine, 5 /-Adenosine Monophosphate and 5 /- Adenosine Diphosphate [PDF]

, 2009
Gastric erosions were induced in rats with indomethacin, 5-hydoxytryptamine (5-HT) or reserpine. Three adenine compounds adenosine, adenosine, 5 /-adenosine monophosphate (AMP) and 5 /- adenosine diphosphate (ADP) were found to protect against the ...
Anosike, CA, Ezekwe, CI, Nwodo, OFC
core   +2 more sources

Neurogenetics of the Human Adenosine Receptor Genes: Genetic Structures and Involvement in Brain Diseases [PDF]

Journal of Caffeine and Adenosine Research, New Rochelle, N.Y. : Mary Ann Liebert, Inc., [2018]-, 2019, 9 (3), pp.73-88, 2020
Adenosine receptors are G-protein-coupled receptors involved in a wide range of physiological and pathological phenomena in most mammalian systems. All four receptors are widely expressed in the central nervous system, where they modulate neurotransmitter release and neuronal plasticity. A large number of gene association studies have shown that common
arxiv   +1 more source

Platelet aggregation and quality control of platelet concentrates produced in the Amazon Blood Bank

Revista Brasileira de Hematologia e Hemoterapia, 2011
BACKGROUND: The study of platelet aggregation is essential to assess in vitro platelet function by different platelet activation pathways. OBJECTIVE: To assess aggregation and biochemical parameters of random platelet concentrates produced at the ...
Maria José Dantas Coêlho, Taysa de Castro Monteiro, Felicien Gonçalves Vasquez, Kátia Luz Torres Silva, Kleber Sandro Brasil dos Santos, Viviana Maria Araújo de Oliveira, Francimary de Oliveira Cavalcante   +6 more
doaj   +1 more source

Altered chemomechanical coupling causes impaired motility of the kinesin-4 motors KIF27 and KIF7. [PDF]

, 2018
Kinesin-4 motors play important roles in cell division, microtubule organization, and signaling. Understanding how motors perform their functions requires an understanding of their mechanochemical and motility properties.
Blasius, T Lynne, Cochran, Jared C, Grant, Barry J, Jariwala, Shashank, Verhey, Kristen J, Walker, Benjamin, Yue, Yang, Zhang, Stephanie   +7 more
core   +2 more sources

Utilization of a deoxynucleoside diphosphate substrate by HIV reverse transcriptase [PDF]

, 2008
Background: Deoxynucleoside triphosphates (dNTPs) are the normal substrates for DNA sysnthesis is catalyzed by polymerases such as HIV-1 reverse transcriptase (RT).
A Bevington, A Mas, AJ Smith, B Selmi, BA Barshop, BA Mulder, BR Bochner, C Cruchaga, C Isnard Bagnis, CK Tan, D Arion, EF Pettersen, G Pontarin, G Pontarin, G Yang, G Yang, GJ Kemp, H Huang, H Ling, H Pelletier, H Pelletier, HK Schachman, IA Nazarenko, K Bebenek, KL White, Kornberg, Linqi Zhang, M Rigourd, MC Franklin, Michael A. Parniak, MJ Bessman, MK Kukhanova, N Sluis-Cremer, PJ Rothwell, PL Boyer, PM Burgers, PM Burgers, PR Meyer, PR Meyer, PR Meyer, PR Meyer, PR Meyer, RS Fletcher, S Dharmasena, Scott J. Garforth, SJ Garforth, SV Doronin, SV Doronin, TA Kunkel, TA Rozovskaya, TA Steitz, UM Parikh, Vinayaka R. Prasad, Z Gu   +53 more
core   +7 more sources

Crystallization of Adenylylsulfate Reductase from Desulfovibrio gigas: A Strategy Based on Controlled Protein Oligomerization [PDF]

, 2011
Adenylylsulfate reductase (adenosine 5′-phosphosulfate reductase, APS reductase or APSR, E.C.1.8.99.2) catalyzes the conversion of APS to sulfite in dissimilatory sulfate reduction. APSR was isolated and purified directly from massive anaerobically grown
Chan, Sunney I., Chen, Chun-Jung, Chiang, Yuan-Lan, Chuankhayan, Phimonphan, Fang, Jou-Yin, Hsieh, Yin-Cheng, Huang, Yen-Chieh, Liu, Ming-Yih, Wang, Vincent C.-C., Yang, Ming-Chi   +9 more
core   +1 more source

Neurochemical measurement of adenosine in discrete brain regions of five strains of inbred mice. [PDF]

PLoS ONE, 2014
Adenosine (ADO), a non-classical neurotransmitter and neuromodulator, and its metabolites adenosine triphosphate (ATP), adenosine diphosphate (ADP) and adenosine monophosphate (AMP), have been shown to play an important role in a number of biochemical ...
Amar K Pani, Yun Jiao, Kenneth J Sample, Richard J Smeyne   +3 more
doaj   +1 more source

The ART of tumor immune escape

OncoImmunology, 2022
We recently identified the adenosine-5′-diphosphate (ADP)–ribosyltransferase-1 (ART1) as a novel immune checkpoint expressed by cancer cells. ART1 utilizes free nicotinamide adenine dinucleotide (NAD+) in the tumor microenvironment (TME) to mono-ADP ...
Erik Wennerberg, Sumit Mukherjee, Ricardo M. Sainz, Brendon M. Stiles   +3 more
doaj   +1 more source