Adenosine Triphosphate and Carbon Efficient Route to Second Generation Biofuel Isopentanol. [PDF]
, 2020 Climate change necessitates the development of CO2 neutral or negative routes to chemicals currently produced from fossil carbon. In this paper we demonstrate a pathway from the renewable resource glucose to next generation biofuel isopentanol by pairing
Chiniquy, Jennifer +9 more
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Ultraslow water-mediated transmembrane interactions regulate the activation of A$_{\text{2A}}$ adenosine receptor [PDF]
Biophys. J. (2016) vol. 111, 1180-1191, 2016 Water molecules inside G-protein coupled receptor have recently been spotlighted in a series of crystal structures. To decipher the dynamics and functional roles of internal waters in GPCR activity, we studied A$_{\text{2A}}$ adenosine receptor using $\mu$sec-molecular dynamics simulations.
arxiv +1 more source
Apyrase treatment prevents ischemia–reperfusion injury in rat lung isografts [PDF]
, 2009 ObjectiveEndothelial cells express the ectoenzyme ectonucleoside adenosine triphosphate diphosphohydrolase, an apyrase that inhibits vascular inflammation by catalyzing the hydrolysis of adenosine triphosphate and adenosine diphosphate.
Chen, Ridong +11 more
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Broadband terahertz time-domain spectroscopy and fast FMCW imaging: principle and applications [PDF]
, 2020 We report a broadband terahertz time-domain spectroscopy (THz-TDS) which enables twenty vibrational modes of adenosine nucleoside to be resolved in a wide frequency range of 1-20 THz. The observed spectroscopic features of adenosine are in good agreement with the published spectra obtained using Fourier Transform Infrared Spectroscopy (FTIR) and Raman ...
arxiv +1 more source
Potentiation of thrombus instability: a contributory mechanism to the effectiveness of antithrombotic medications [PDF]
, 2018 © The Author(s) 2018The stability of an arterial thrombus, determined by its structure and ability to resist endogenous fibrinolysis, is a major determinant of the extent of infarction that results from coronary or cerebrovascular thrombosis.
A Gast +66 more
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UV resistance of nucleosides -- an experimental approach [PDF]
, 2020 The emergence of life on Earth is a highly discussed but still unsolved question. Current research underlines the importance of environments within close proximity to the Earth's surface as they can solve long-standing problems such as polymerization of nucleotides and phosphorylation of nucleosides.
arxiv +1 more source
Platelet inhibitory effects of the Phase 3 anticancer and normal tissue cytoprotective agent, RRx-001. [PDF]
, 2018 The platelet inhibitory effects of the Phase 3 anticancer agent and nitric oxide (NO) donor, RRx-001, (1-bromoacetyl-3,3-dinitroazetidine) were examined ex vivo and compared with the diazeniumdiolate NO donor, diethylenetriamine NONOate (DETA-NONOate ...
Bryan Oronsky +3 more
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Model for the unidirectional motion of a dynein molecule [PDF]
Phys. Rev. E 77, 051916 (2008), 2008 Cytoplasmic dyneins transport cellular organelles by moving on a microtubule filament. It has been found recently that depending on the applied force and the concentration of the adenosine triphosphate (ATP) molecules, dynein's step size varies. Based on these studies, we propose a simple model for dynein's unidirectional motion taking into account the
arxiv +1 more source
Inhibition of Gastric Erosion Formations in Rats by Adenosine, 5 /-Adenosine Monophosphate and 5 /- Adenosine Diphosphate [PDF]
, 2009 Gastric erosions were induced in rats with indomethacin, 5-hydoxytryptamine (5-HT) or reserpine. Three adenine compounds adenosine, adenosine, 5 /-adenosine monophosphate (AMP) and 5 /- adenosine diphosphate (ADP) were found to protect against the ...
Anosike, CA, Ezekwe, CI, Nwodo, OFC
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The plant Nudix hydrolase family. [PDF]
, 2008 Nudix hydrolases are a family of proteins defined by a conserved amino-acid sequence GX(5)-EX(7)REUXEEXGU, where U is a hydrophobic residue. These enzymes are widely distributed among all classes of organisms and catalyze, with varying degrees of ...
Kraszewska, Elzbieta
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