Results 61 to 70 of about 288,808 (285)

Disruption of insulin signalling preserves bioenergetic competence of mitochondria in ageing Caenorhabditis elegans [PDF]

, 2010
Background: The gene daf-2 encodes the single insulin/insulin growth factor-1-like receptor of Caenorhabditis elegans. The reduction-of-function allele e1370 induces several metabolic alterations and doubles lifespan.
Braeckman, Bart, Brys, Kristel, Castelein, Natascha, Matthijssens, Filip, Vanfleteren, Jacques   +4 more
core   +3 more sources

IS THE SYNTAX SCORE SUFFICIENT TO ASSESS THE RISK FOR PATIENTS UNDERGOING ELECTIVE PERCUTANEOUS CORONARY INTERVENTIONS?

Атеротромбоз, 2017
The article presents a comparative evaluation of the current clinical angiographic scales in the risk stratification for patients with stable coronary artery disease undergoing elective percutaneous coronary interventions.
E. S. Novikova, A. L. Komarov, E. V. Gus’kova, O. O. Shakhmatova, A. D. Deyev, A. B. Dobrovolsky, A. N. Samko, E. P. Panchenko   +7 more
doaj   +1 more source

Apyrase treatment prevents ischemia–reperfusion injury in rat lung isografts [PDF]

, 2009
ObjectiveEndothelial cells express the ectoenzyme ectonucleoside adenosine triphosphate diphosphohydrolase, an apyrase that inhibits vascular inflammation by catalyzing the hydrolysis of adenosine triphosphate and adenosine diphosphate.
Chen, Ridong, Das, Nitin A., Gelman, Andrew E., Jeong, Soon Seog, Kreisel, Daniel, Krupnick, Alexander S., Lai, Jiaming, Li, Wenjun, Lin, Xue, Okazaki, Mikio, Patterson, G.A., Sugimoto, Seiichiro   +11 more
core   +1 more source

Ectonucleoside Triphosphate Diphosphohydrolase-1/CD39 Affects the Response to ADP of Female Rat Platelets

Frontiers in Pharmacology, 2020
There is evidence that an imbalance of extracellular purine levels may be associated with increased cardiovascular risk. Platelets play a pivotal role in vascular homeostasis and thrombosis and are important source of purine nucleotides and nucleosides ...
Elisabetta Caiazzo, Rossella Bilancia, Antonietta Rossi, Armando Ialenti, Carla Cicala   +4 more
doaj   +1 more source

Validation of a Fast and Simple HPLC-UV Method for the Quantification of Adenosine Phosphates in Human Bronchial Epithelial Cells

Molecules, 2021
A new HPLC method for the simultaneous quantitative analysis of adenosine triphosphate (ATP), adenosine diphosphate (ADP), and adenosine monophosphate (AMP) was developed and validated.
Ana Teresa Juarez-Facio, Violaine Martin de Lagarde, Christelle Monteil, Jean-Marie Vaugeois, Cécile Corbiere, Tiphaine Rogez-Florent   +5 more
doaj   +1 more source

KATP Channel Openers Have Opposite Effects on Mitochondrial Respiration Under Different Energetic Conditions [PDF]

, 2008
Mitochondrial (m) KATP channel opening has been implicated in triggering cardiac preconditioning. Its consequence on mitochondrial respiration, however, remains unclear. We investigated the effects of two different KATP channel openers and antagonists on
Camara, Amadou K.S., Eells, Janis T., Heinen, André, Henry, Michele M., Riess, Matthias L., Stowe, David F.   +5 more
core   +2 more sources

Characterization of a novel pyruvate kinase from Trichinella spiralis and its participation in sugar metabolism, larval molting and development

PLoS Neglected Tropical Diseases, 2022
Background Pyruvate kinase widely exists in many parasites and plays an important role in the energy production for the parasites. Pyruvate kinase might be a potential drug target for killing the parasites.
Wen Wen Yue, Shu Wei Yan, Ru Zhang, Yong Kang Cheng, Ruo Dan Liu, Shao Rong Long, Xi Zhang, Zhong Quan Wang, Jing Cui   +8 more
doaj  

Nucleotides: Structure and Properties [PDF]

, 2005
Nucleotides consist of a nitrogen-containing base, a five-carbon sugar, and one or more phosphate groups. Cells contain many types of nucleotides, which play a central role in a wide variety of cellular processes, including metabolic regulation and the ...
Bowater, RP
core   +1 more source

The plant Nudix hydrolase family. [PDF]

, 2008
Nudix hydrolases are a family of proteins defined by a conserved amino-acid sequence GX(5)-EX(7)REUXEEXGU, where U is a hydrophobic residue. These enzymes are widely distributed among all classes of organisms and catalyze, with varying degrees of ...
Kraszewska, Elzbieta
core  

Attenuation of ischemic liver injury by monoclonal anti-endothelin antibody, awETN40 [PDF]

, 1997
Background: Enhanced production of endothelin-1 (ET1), vasoconstrictive 21 amino acids produced by endothelial cells during ischemia and after reperfusion of the liver, is known to cause sinusoidal constriction and microcirculatory disturbances, which ...
Ishizaki, N, Jin, MB, Lee, R, Shimamura, T, Starzl, TE, Subbotin, V, Todo, S, Totsuka, E, Urakami, A, Zhang, S, Zhu, Y   +10 more
core   +1 more source