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Adenosine monophosphate deaminase deficiency

Definitions, 2020
Adenosine monophosphate (AMP) deaminase deficiency is a condition that can affect the muscles used for movement (skeletal muscles). In many affected individuals, AMP deaminase deficiency does not cause any symptoms.
G. Berghe
semanticscholar   +1 more source

A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling

Nature Communications, 2021
Cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) is normally induced by innate immunity sensing for protection from pathogens. Here the authors show that cGAMP is also upstream of DNA damage signaling by activating ATM-CHK2-mediated repair ...
Daipayan Banerjee, Kurt Langberg, Salar Abbas, Eric Odermatt, Praveen Yerramothu, Martin Volaric, Matthew A. Reidenbach, Kathy J. Krentz, C. Dustin Rubinstein, David L. Brautigan, Tarek Abbas, Bradley D. Gelfand, Jayakrishna Ambati, Nagaraj Kerur   +13 more
doaj   +1 more source

Hydrophilic interaction liquid chromatography coupled to quadrupole-time-of-flight mass spectrometry for determination of nuclear and cytoplasmatic contents of nucleotides, nucleosides and their nucleobases in food yeasts

Talanta Open, 2021
Hydrophilic interaction liquid chromatography using a zwitterionic phase, coupled with high-resolution mass spectrometry based on quadrupole and time-of-flight mass analyser (HILIC-Q-TOF-MS) is applied for the determination of four nucleobases (adenine ...
Marta Pastor-Belda, Inmaculada Fernández-Caballero, Natalia Campillo, Natalia Arroyo-Manzanares, Manuel Hernández-Córdoba, Pilar Viñas   +5 more
doaj   +1 more source

Dietary intake of fructose increases purine de novo synthesis: A crucial mechanism for hyperuricemia

Frontiers in Nutrition, 2022
BackgroundFructose consumption is a potential risk factor for hyperuricemia because uric acid (UA) is a byproduct of fructose metabolism caused by the rapid consumption of adenosine triphosphate and accumulation of adenosine monophosphate (AMP) and other
Pengfei Zhang, Pengfei Zhang, Huimin Sun, Xinyu Cheng, Yajing Li, Yanli Zhao, Wuxuan Mei, Xing Wei, Hairong Zhou, Yunbo Du, Changchun Zeng   +10 more
doaj   +1 more source

Cyclic Guanosine Monophosphate–Adenosine Monophosphate Synthase (cGAS), a Multifaceted Platform of Intracellular DNA Sensing

Frontiers in Immunology, 2021
Innate immune pathways are the first line of cellular defense against pathogen infections ranging from bacteria to Metazoa. These pathways are activated following the recognition of pathogen associated molecular patterns (PAMPs) by membrane and cytosolic
Eloi R. Verrier, Christelle Langevin
doaj   +1 more source

Alkaline Phosphatase, Soluble Extracellular Adenine Nucleotides, and Adenosine Production after Infant Cardiopulmonary Bypass.

PLoS ONE, 2016
RationaleDecreased alkaline phosphatase activity after infant cardiac surgery is associated with increased post-operative cardiovascular support requirements.
Jesse A Davidson, Tracy Urban, Suhong Tong, Mark Twite, Alan Woodruff, Paul E Wischmeyer, Jelena Klawitter   +6 more
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Normobaric oxygen therapy attenuates hyperglycolysis in ischemic stroke

Neural Regeneration Research, 2021
Normobaric oxygen therapy has gained attention as a simple and convenient means of achieving neuroprotection against the pathogenic cascade initiated by acute ischemic stroke.
Zhe Cheng, Feng-Wu Li, Christopher R Stone, Kenneth Elkin, Chang-Ya Peng, Redina Bardhi, Xiao-Kun Geng, Yu-Chuan Ding   +7 more
doaj   +1 more source

Differences in growth and alkaline phosphatase activity between Microcystis aeruginosa and Chlorella pyrenoidosa in response to media with different organic phosphorus

Journal of Limnology, 2011
The growth of Microcystis aeruginosa and Chlorella pyrenoidosa in three dissolved organic phosphorus sources (glucose-1- phosphate, adenosine triphosphate, cyclic-adenosine monophosphate) were studied in cultures separated by a dialysis membrane. Results
Yang YU, Min ZHANG, Fanxiang KONG, Xiaoli SHI, Shanqin QIAN   +4 more
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Hepatitis B Virus Evasion From Cyclic Guanosine Monophosphate–Adenosine Monophosphate Synthase Sensing in Human Hepatocytes

Hepatology, 2018
Chronic hepatitis B virus (HBV) infection is a major cause of chronic liver disease and cancer worldwide. The mechanisms of viral genome sensing and the evasion of innate immune responses by HBV infection are still poorly understood. Recently, the cyclic
Eloi R. Verrier, Seung-Ae Yim, Laura Heydmann, Houssein El Saghire, Charlotte Bach, Vincent Turon-Lagot, L. Mailly, S. Durand, J. Lucifora, D. Durantel, P. Pessaux, N. Manel, I. Hirsch, M. Zeisel, N. Pochet, C. Schuster, T. Baumert   +16 more
semanticscholar   +1 more source

Amplification of Chirality by Adenosine Monophosphate-Capped Luminescent Gold Nanoclusters in Nematic Lyotropic Chromonic Liquid Crystal Tactoids

ACS Omega, 2019
Amplification of chirality across length scales is a key concept pertinent to many models aiming to unravel the origin of homochirality. Tactoids of lyotropic chromonic liquid crystals formed by DNA, dyes, and other flat ionic molecules in water in the ...
Sasan Shadpour, Julie P Vanegas, Ahlam Nemati, T. Hegmann   +3 more
semanticscholar   +1 more source