Results 21 to 30 of about 225,984 (308)

Development of Single-Molecule Electrical Identification Method for Cyclic Adenosine Monophosphate Signaling Pathway

open access: yesNanomaterials, 2021
Cyclic adenosine monophosphate (cAMP) is an important research target because it activates protein kinases, and its signaling pathway regulates the passage of ions and molecules inside a cell.
Yuki Komoto   +2 more
doaj   +1 more source

New Insights into the Basic and Translational Aspects of AMPK Signaling

open access: yesCells, 2023
5′-adenosine monophosphate (AMP)-activated protein kinase (AMPK) is an enzyme regulating numerous cellular processes involved in cell survival as well as health- and lifespan [...]
Yury Ladilov, Muhammad Aslam
doaj   +1 more source

The dipeptidyl peptidase-IV inhibitor gemigliptin alone or in combination with NVP-AUY922 has a cytotoxic activity in thyroid carcinoma cells

open access: yesTumor Biology, 2017
The effect of the dipeptidyl peptidase-IV inhibitor gemigliptin alone or in combination with the heat shock protein 90 inhibitor NVP-AUY922 (AUY922) on survival of thyroid carcinoma cells was elucidated. The SW1736 and TPC-1 human thyroid carcinoma cells
Si Hyoung Kim   +6 more
doaj   +1 more source

Determination of total potentially available nucleosides in bovine milk [PDF]

open access: yes, 2010
Bovine colostrum and milk samples were collected from two herds over the course of the first month post-partum, pooled for each herd by stage of lactation and total potentially available nucleosides were determined.
Gill, Brendon D.   +2 more
core   +2 more sources

Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase.

open access: yesPLoS ONE, 2019
Cordycepin is an efficient component of Cordyceps spp, a traditional Chinese medicine widely used for healthcare in China, and has been recently acted as a strong anticancer agent for clinic.
Feng Huang   +4 more
doaj   +1 more source

Human Deoxycytidine Kinase Is a Valuable Biocatalyst for the Synthesis of Nucleotide Analogues [PDF]

open access: yes, 2019
Natural ribonucleoside-5’-monophosphates are building blocks for nucleic acids which are used for a number of purposes, including food additives. Their analogues, additionally, are used in pharmaceutical applications.
Hellendahl, Katja F.   +4 more
core   +1 more source

Phosphorus availability regulates intracellular nucleotides in marine eukaryotic phytoplankton

open access: yesLimnology and Oceanography Letters, 2017
Marine eukaryotic phytoplankton adapt to low phosphorus (P) in the oceans through a variety of step‐wise mechanisms including lipid substitution and decreased nucleic acid content.
Elizabeth B. Kujawinski   +6 more
doaj   +1 more source

Bradykinin postconditioning protects rat hippocampal neurons after restoration of spontaneous circulation following cardiac arrest via activation of the AMPK/mTOR signaling pathway

open access: yesNeural Regeneration Research, 2022
Bradykinin (BK) is an active component of the kallikrein-kinin system that has been shown to have cardioprotective and neuroprotective effects. We previously showed that BK postconditioning strongly protects rat hippocampal neurons upon restoration of ...
Shi-Rong Lin   +7 more
doaj   +1 more source

The effect of red ginseng and ginseng leaves on the substance and energy metabolism in hypothyroidism rats

open access: yesJournal of Ginseng Research, 2017
Background: Recent studies have revealed that the properties Traditional Chinese Medicine is mostly associated with are substance and energy metabolism.
Hang Xiao   +3 more
doaj   +1 more source

The T2238C human atrial natriuretic peptide molecular variant and the risk of cardiovascular diseases [PDF]

open access: yes, 2018
Atrial natriuretic peptide (ANP) is a cardiac hormone which plays important functions to maintain cardio-renal homeostasis. The peptide structure is highly conserved among species. However, a few gene variants are known to fall within the human ANP gene.
Bianchi, Franca   +5 more
core   +2 more sources

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