Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC [PDF]
Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways.
Alberto Contreras-Sanz +60 more
core +2 more sources
Normobaric oxygen therapy attenuates hyperglycolysis in ischemic stroke
Normobaric oxygen therapy has gained attention as a simple and convenient means of achieving neuroprotection against the pathogenic cascade initiated by acute ischemic stroke.
Zhe Cheng +7 more
doaj +1 more source
Bacillus anthracis edema factor substrate specificity: evidence for new modes of action [PDF]
Since the isolation of Bacillus anthracis exotoxins in the 1960s, the detrimental activity of edema factor (EF) was considered as adenylyl cyclase activity only.
Agrawal +94 more
core +2 more sources
The growth of Microcystis aeruginosa and Chlorella pyrenoidosa in three dissolved organic phosphorus sources (glucose-1- phosphate, adenosine triphosphate, cyclic-adenosine monophosphate) were studied in cultures separated by a dialysis membrane. Results
Yang YU +4 more
doaj +1 more source
The role of cyclic nucleotide on fetal and neonantal erythropoiesis [PDF]
For the purpose to reveal the changes in stimulatory effect of dibutyryl-cyclic- AMP on erythropoiesis during ontogenetic development, the author studied syntheses of DNA, RNA and protein of erythroid cells in fetal liver, neonatal and adult bone marrows
Tada, Hiroshi
core +1 more source
Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review [PDF]
Background A growing number of epidemiological studies indicate that metabolic syndrome (MetS) and its associated features play a key role in the development of certain degenerative brain disorders, including Alzheimer’s disease and vascular dementia ...
Bell, J.D. +9 more
core +1 more source
3',5'-Cyclic Adenosine Monophosphate- and Ca2+-Calmodulin-Dependent Endogenous Protein Phosphorylation Activity in Membranes of the Bovine Chromaffin Secretory Vesicles: Identification of Two Phosphorylated Components as Tyrosine Hydroxylase and Protein Kinase Regulatory Subunit Type II [PDF]
: Membranes of the secretory vesicles from bovine adrenal medulla were investigated for the presence of the endogenous protein phosphorylation activity. Seven phosphoprotein bands in the molecular weight range of 250,000 to 30,000 were observed by means ...
Amy C. M. +27 more
core +1 more source
Tensin links energy metabolism to extracellular matrix assembly. [PDF]
The regulation of integrin function is key to fundamental cellular processes, including cell migration and extracellular matrix (ECM) assembly. In this issue, Georgiadou et al. (2017. J. Cell Biol.
Calderwood +15 more
core +3 more sources
Crosstalk between G-protein and Ca2+ pathways switches intracellular cAMP levels [PDF]
Cyclic adenosine monophosphate and cyclic guanosine monophosphate are universal intracellular messengers whose concentrations are regulated by molecular networks comprised of different isoforms of the synthases adenylate cyclase or guanylate cyclase and ...
A Dietz +22 more
core +2 more sources
Renin–angiotensin system and adenosine monophosphate–activated protein kinase signaling pathway both play important roles in carcinogenesis, but the interplay of renin–angiotensin system and adenosine monophosphate–activated protein kinase in ...
Ke-Ke Yang +3 more
doaj +1 more source

