Results 21 to 30 of about 347,631 (311)

Adenosine Monophosphate (AMP)-Activated Protein Kinase: A New Target for Nutraceutical Compounds

International Journal of Molecular Sciences, 2017
Adenosine monophosphate-activated protein kinase (AMPK) is an important energy sensor which is activated by increases in adenosine monophosphate (AMP)/adenosine triphosphate (ATP) ratio and/or adenosine diphosphate (ADP)/ATP ratio, and increases ...
F. Marín-Aguilar, Luís E. Pavillard, Francesca Giampieri, P. Bullón, M. Cordero   +4 more
semanticscholar   +1 more source

Interaction of renin–angiotensin system and adenosine monophosphate–activated protein kinase signaling pathway in renal carcinogenesis of uninephrectomized rats

Tumor Biology, 2017
Renin–angiotensin system and adenosine monophosphate–activated protein kinase signaling pathway both play important roles in carcinogenesis, but the interplay of renin–angiotensin system and adenosine monophosphate–activated protein kinase in ...
Ke-Ke Yang, Yi Sui, Hui-Rong Zhou, Hai-Lu Zhao   +3 more
doaj   +1 more source

Development of Single-Molecule Electrical Identification Method for Cyclic Adenosine Monophosphate Signaling Pathway

Nanomaterials, 2021
Cyclic adenosine monophosphate (cAMP) is an important research target because it activates protein kinases, and its signaling pathway regulates the passage of ions and molecules inside a cell.
Yuki Komoto, Takahito Ohshiro, Masateru Taniguchi   +2 more
doaj   +1 more source

Metformin augments doxorubicin cytotoxicity in mammary carcinoma through activation of adenosine monophosphate protein kinase pathway

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017
Since the incidence of breast cancer increases dramatically all over the world, the search for effective treatment is an urgent need. Metformin has demonstrated anti-tumorigenic effect both in vivo and in vitro in different cancer types.
N. El-Ashmawy, N. Khedr, H. El-bahrawy, Hend E Abo Mansour   +3 more
semanticscholar   +1 more source

New Insights into the Basic and Translational Aspects of AMPK Signaling

Cells, 2023
5′-adenosine monophosphate (AMP)-activated protein kinase (AMPK) is an enzyme regulating numerous cellular processes involved in cell survival as well as health- and lifespan [...]
Yury Ladilov, Muhammad Aslam
doaj   +1 more source

The dipeptidyl peptidase-IV inhibitor gemigliptin alone or in combination with NVP-AUY922 has a cytotoxic activity in thyroid carcinoma cells

Tumor Biology, 2017
The effect of the dipeptidyl peptidase-IV inhibitor gemigliptin alone or in combination with the heat shock protein 90 inhibitor NVP-AUY922 (AUY922) on survival of thyroid carcinoma cells was elucidated. The SW1736 and TPC-1 human thyroid carcinoma cells
Si Hyoung Kim, Jun Goo Kang, Chul Sik Kim, Sung-Hee Ihm, Moon Gi Choi, Hyung Joon Yoo, Seong Jin Lee   +6 more
doaj   +1 more source

Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase.

PLoS ONE, 2019
Cordycepin is an efficient component of Cordyceps spp, a traditional Chinese medicine widely used for healthcare in China, and has been recently acted as a strong anticancer agent for clinic.
Feng Huang, Weihui Li, Hui Xu, Huafeng Qin, Zheng-Guo He   +4 more
doaj   +1 more source

Phosphorus availability regulates intracellular nucleotides in marine eukaryotic phytoplankton

Limnology and Oceanography Letters, 2017
Marine eukaryotic phytoplankton adapt to low phosphorus (P) in the oceans through a variety of step‐wise mechanisms including lipid substitution and decreased nucleic acid content.
Elizabeth B. Kujawinski, Krista Longnecker, Harriet Alexander, Sonya T. Dyhrman, Cara L. Fiore, Sheean T. Haley, Winifred M. Johnson   +6 more
doaj   +1 more source

Bradykinin postconditioning protects rat hippocampal neurons after restoration of spontaneous circulation following cardiac arrest via activation of the AMPK/mTOR signaling pathway

Neural Regeneration Research, 2022
Bradykinin (BK) is an active component of the kallikrein-kinin system that has been shown to have cardioprotective and neuroprotective effects. We previously showed that BK postconditioning strongly protects rat hippocampal neurons upon restoration of ...
Shi-Rong Lin, Qing-Ming Lin, Yu-Jia Lin, Xin Qian, Xiao-Ping Wang, Zheng Gong, Feng Chen, Bin Song   +7 more
doaj   +1 more source

The effect of red ginseng and ginseng leaves on the substance and energy metabolism in hypothyroidism rats

Journal of Ginseng Research, 2017
Background: Recent studies have revealed that the properties Traditional Chinese Medicine is mostly associated with are substance and energy metabolism.
Hang Xiao, Cheng Tan, Guanlin Yang, Deqiang Dou   +3 more
doaj   +1 more source