Results 31 to 40 of about 165,902 (383)

Development of Single-Molecule Electrical Identification Method for Cyclic Adenosine Monophosphate Signaling Pathway

open access: yesNanomaterials, 2021
Cyclic adenosine monophosphate (cAMP) is an important research target because it activates protein kinases, and its signaling pathway regulates the passage of ions and molecules inside a cell.
Yuki Komoto   +2 more
doaj   +1 more source

Cyclic adenosine monophosphate, CA++, and membranes. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1968
Since the initial discovery of cyclic 3',5'-adenosine monophosphate (3',5'AMP) by Rall, Sutherland, and Berthet' and its role in glycogenolysis in the liver,2 evidence has accumulated indicating that this nucleotide is an intermediate in the action of many peptide hormones.3-9 More recently it has also been implicated in the release of insulin from the
Howard Rasmussen, Alan Tenenhouse
openaire   +3 more sources

New Insights into the Basic and Translational Aspects of AMPK Signaling

open access: yesCells, 2023
5′-adenosine monophosphate (AMP)-activated protein kinase (AMPK) is an enzyme regulating numerous cellular processes involved in cell survival as well as health- and lifespan [...]
Yury Ladilov, Muhammad Aslam
doaj   +1 more source

Photoactivation of trans diamine platinum complexes in aqueous solution and effect on reactivity towards nucleotides [PDF]

open access: yes, 2010
We show that UVA irradiation (365 nm) of the Pt-IV complex trans,trans,trans-[(PtCl2)-Cl-IV(OH)(2)(dimethylamine) (isopropylamine)] (1), induces reduction to Pt-II photoproducts.
Cubo, Leticia   +5 more
core   +1 more source

Neurogenetics of the Human Adenosine Receptor Genes: Genetic Structures and Involvement in Brain Diseases [PDF]

open access: yesJournal of Caffeine and Adenosine Research, New Rochelle, N.Y. : Mary Ann Liebert, Inc., [2018]-, 2019, 9 (3), pp.73-88, 2020
Adenosine receptors are G-protein-coupled receptors involved in a wide range of physiological and pathological phenomena in most mammalian systems. All four receptors are widely expressed in the central nervous system, where they modulate neurotransmitter release and neuronal plasticity. A large number of gene association studies have shown that common
arxiv   +1 more source

The dipeptidyl peptidase-IV inhibitor gemigliptin alone or in combination with NVP-AUY922 has a cytotoxic activity in thyroid carcinoma cells

open access: yesTumor Biology, 2017
The effect of the dipeptidyl peptidase-IV inhibitor gemigliptin alone or in combination with the heat shock protein 90 inhibitor NVP-AUY922 (AUY922) on survival of thyroid carcinoma cells was elucidated. The SW1736 and TPC-1 human thyroid carcinoma cells
Si Hyoung Kim   +6 more
doaj   +1 more source

Gastroprotective effects of oral nucleotide administration [PDF]

open access: yes, 2006
BACKGROUND AND AIMS: Nucleotides form the building blocks of DNA and are marketed as dietary supplements, alone or in combination with other ingredients, to promote general health.
Belo, A   +4 more
core   +2 more sources

Modelling of Dictyostelium Discoideum Movement in Linear Gradient of Chemoattractant [PDF]

open access: yesSoft Matter,Vol. 13, pp. 8209-8222 (2017), 2018
Chemotaxis is a ubiquitous biological phenomenon in which cells detect a spatial gradient of chemoattractant, and then move towards the source. Here we present a position-dependent advection-diffusion model that quantitatively describes the statistical features of the chemotactic motion of the social amoeba {\it Dictyostelium discoideum} in a linear ...
arxiv   +1 more source

c-di-AMP: An essential molecule in the signaling pathways that regulate the viability and virulence of gram-positive bacteria [PDF]

open access: yes, 2017
Signal transduction pathways enable organisms to monitor their external environment and adjust gene regulation to appropriately modify their cellular processes.
Cho, Kyu Hong   +2 more
core   +2 more sources

The role of cyclic nucleotide on fetal and neonantal erythropoiesis [PDF]

open access: yes, 1974
For the purpose to reveal the changes in stimulatory effect of dibutyryl-cyclic- AMP on erythropoiesis during ontogenetic development, the author studied syntheses of DNA, RNA and protein of erythroid cells in fetal liver, neonatal and adult bone marrows
Tada, Hiroshi
core   +1 more source

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