Results 141 to 150 of about 350,006 (309)

In Vitro Transcription of the Gal Operon Requires Cyclic Adenosine Monophosphate and Cyclic Adenosine Monophosphate Receptor Protein

, 1971
S. Peter Nissley, Wayne B. Anderson, Max E. Gottesman, Robert L. Perlman, Ira Pastan   +4 more
openalex   +1 more source

Subclasses of external adenosine receptors. [PDF]

, 1980
Constantine Londos, Dermot M.F. Cooper, J. Wolff   +2 more
openalex   +1 more source

Topological Scaffold‐Based Trispecific Recombinant Protein‐Drug Conjugates for Solid Tumor Eradication

Advanced Science, EarlyView.
A novel tri‐specific recombinant protein and its drug conjugate are developed, named sRP‐EHI and sRPDC‐EHI, which feature a star‐shaped topological structure. It can simultaneously bind the EGFR, HER2, and integrin αvβ3 overexpressed in cancer cells.
Huiyi Jiang, Yang Yuan, Xiaoke Zhang, Weizhi Chen, Hui Mao, Baorui Liu, Xiqun Jiang   +6 more
wiley   +1 more source

Binding of 125I-labeled glucagon and glucagon-stimulated accumulation of adenosine 3‘:5‘-monophosphate in isolated intact rat hepatocytes. Evidence for receptor heterogeneity.

, 1978
O. Sonne, Trond Berg, Thoralf Christoffersen   +2 more
openalex   +1 more source

Pinosylvin Inhibits Inflammatory and Osteoclastogenesis via NLRP3 Inflammasome

Advanced Science, EarlyView.
Pinosylvin blocks LPS and RANKL induced NEK7/NLRP3 interaction, inhibiting NLRP3 inflammasome oligomerization and assembly, reducing IL‐1β maturation and GSDMD cleavage, and improving the inflammatory microenvironment and abnormal osteoclastogenesis. Abstract Pro‐inflammatory cytokines such as TNF, IL‐1, and IL‐6 trigger aberrant osteoclastogenesis and
Wei Zhang, Xiangbing Wu, Wenming Li, Haifeng Zhang, Yijun Wang, Jing Xu, Wenhao Li, Yi Qin, Zebin Wu, Gaoran Ge, Shujun Lv, Lu Mao, Liangliang Wang, Dechun Geng   +13 more
wiley   +1 more source

Novel Adenosine Receptor Antagonists for Treating Cancer and Immune-Related Disorders. [PDF]

ACS Med Chem Lett, 2023
Sabnis RW.
europepmc   +1 more source

Experimental approaches to understanding the role of protein phosphorylation in the regulation of neuronal function [PDF]

, 1983
Studies by Earl Sutherland and his colleagues on hormonal regulation of the breakdown of glycogen in liver resulted in the discovery that the first step in the action of many hormones is to increase the synthesis of cAMP by activating adenylate cyclase ...
Kennedy, Mary B.
core  

Adenosine 3‘:5‘-monophosphate receptor proteins in mammalian brain.

, 1978
Ulrich Walter, Philip D. Kanof, Howard Schulman, Paul Greengard   +3 more
openalex   +1 more source

Characterization and localization of adenosine receptors in rat spinal cord [PDF]

, 1984
JD Geiger, FS LaBella, J.I. Nagy
openalex   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source