Results 141 to 150 of about 2,608,509 (268)

Molecular Determinants of CGS21680 Binding to the Human Adenosine A2A Receptor

Molecular Pharmacology, 2015
G. Lebon, P. Edwards, A. Leslie, C. Tate
semanticscholar   +1 more source

Conductive Microneedles Loaded With Polyphenol‐Engineered Exosomes Reshape Diabetic Neurovascular Niches for Chronic Wound Healing

Advanced Science, EarlyView.
This study establishes a bio‐electroceutical interface by synergizing engineered exosome‐derived biological signals with electroconductive microneedle‐delivered electrical cues, achieving dual‐pathway reprogramming of the diabetic neurovascular niches and accelerating wound healing. Abstract Diabetic wound healing remains a major clinical challenge due
Di Liu, Jingxian Gao, Xueling Wu, Xinxin Hao, Wenxiu Hu, Lu Han   +5 more
wiley   +1 more source

Adenosine receptor subtype modulators: Insight into molecular mechanisms and their therapeutic application. [PDF]

Am J Transl Res
Solanki N, Dodiya R, Vejpara D, Azad S, Patel M, Patel S, Shah U, Soni A, Maheshwari R, Navale A, Patel A, Patel S, Sheth D, Tirgar P, R R.   +14 more
europepmc   +1 more source

Structure of an Agonist-Bound Human A2A Adenosine Receptor

Science, 2011
Fei Xu, Huixian Wu, V. Katritch, G. Han, K. Jacobson, Zhang-Guo Gao, V. Cherezov, R. Stevens   +7 more
semanticscholar   +1 more source

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

Advanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying, Qi Wang, Dejian Li, Yao Wang, Pengfang Zhang, Chengqing Yi, Rui Zhu   +6 more
wiley   +1 more source

Adenosine Receptor Mechanisms Underlying Bladder Dysfunction in Male Rats With Bladder Outlet Obstruction. [PDF]

Neurourol Urodyn
Takaoka EI, Kurobe M, Matsuoka K, Kamijo T, Kimura S, Watton PN, Robertson AM, Yoshimura N.   +7 more
europepmc   +1 more source

Receptors on the neutrophil membrane. I. Flunarizine-adenosine antagonism as detected by 1H-nuclear magnetic resonance relaxation investigations

, 1987
T. Di Perri, Alfredo Orrico, Franco Laghi‐Pasini, Elena Gaggelli, Gianni Valensin   +4 more
openalex   +1 more source

Structural Requirements for RNA Editing in Glutamate Receptor Pre-mRNAs by Recombinant Double-stranded RNA Adenosine Deaminase [PDF]

, 1996
Stefan Maas, Thorsten Melcher, Anne Herb, Peter H. Seeburg, Walter Keller, Sabine Krause, Miyoko Higuchi, Mary A. O’Connell   +7 more
openalex   +1 more source

A Novel Zinc(II) Complex for Sonodynamic Therapy Induces Pyroptosis of Breast Cancer Cells and Enhances Anti‐Tumor Immune Response

Advanced Science, EarlyView.
Although Zinc(II) complexes are effective in photodynamic therapy, their efficacy is limited by the poor tissue penetration of light. This work introduces a novel zinc(II) complex for sonodynamic therapy. Under ultrasound activation, it generates substantial singlet oxygen, induces pyroptosis in breast cancer cells, and promotes anti‐tumor immune ...
Sijie Wen, Dongsheng Tang, Lingpu Zhang, Hanchen Zhang, Zheng Cao, Kong Wai Tan, Xiaojun Wang, Haihua Xiao, Kun Shang   +8 more
wiley   +1 more source

A new approach to psoriasis therapy: photoswitchable A₃ adenosine receptor activation. [PDF]

Purinergic Signal
Cherchi F, Coppi E.
europepmc   +1 more source