Results 121 to 130 of about 4,325,962 (256)

Regadenoson in the detection of coronary artery disease

Vascular Health and Risk Management, 2008
Christiane Buhr1, Mario Gössl2, Raimund Erbel1, Holger Eggebrecht11Department of Cardiology, West-German Heart Center Essen, University of Duisburg-Essen, Essen, Germany; 2Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN 55905,
Christiane Buhr, Mario Gössl, Raimund Erbel, Holger Eggebrecht   +3 more
doaj  

Chemical and pharmacological profile of selective adenosine receptor agonists

, 1996
There is evidence that the purine nucleoside adenosine specifically modulates neurotransmission through the interaction with four cell surface receptors recently classified as A1, A2a, A2b, and A3.
Di Francesco E, S. Vittori, E. Camaioni, R. Volpini, VITTORI, Sauro, CRISTALLI, Gloria, Camaioni E, VOLPINI, Rosaria, E. Di Francesco, G. Cristalli   +9 more
core   +2 more sources

New Strategies in Quantitative Structure-Activity Relationships. Applications to Adenosine Receptor Ligands

, 2006
Over the last years, an increasing number of applications of QSAR (Quantitative Structure-Activity Relationships) appeared in the literature, not only in lead finding and lead optimization, but also in other fields related to drug discovery, such as ...
Borghini, Alice
core   +1 more source

Pharmacological and clinical significance of adenosine receptor antagonists

, 2017
Adenosine receptor agonist play role in treatment of cardiovascular disease. It can regulate the pacemaker activity, atrioventricular conduction, myocardial contractility, it also can reduce the heart rate therefore it can be use in various forms of ...
Niaparast, Maral
core  

Age-related changes in cardiac adenosine receptor expression

, 2004
Adenosine is an important cardioprotective agent that works via several adenosine receptor (ADOR) subtypes to regulate cardiovascular activity. It is well established that functional responses to adenosine decline with age.
Jenner, Tamsin, Jenner, Tamsin L., Mellick, AS, Mellick, Albert S., Jenner, TL, Griffiths, Lyn, Rose’Meyer, Roselyn B., Mellick, Albert, Harrison, Glenn J., Rose'Meyer, Roselyn, Griffiths, Lyn R., Griffiths, LR, Harrison, GJ, Harrison, Glenn, Rose'Meyer, RB   +14 more
core   +1 more source

Adenosine Receptor Agonists Modulate Visceral Hyperalgesia in the Rat

Gut and Liver, 2008
Background/Aims: Adenosine is an endogenous modulator of nociception. Its role in visceral nociception, particularly in visceral hyperalgesia, has not been studied.
doaj   +1 more source

The belated US FDA approval of the adenosine A2A receptor antagonist istradefylline for treatment of Parkinson’s disease

Purinergic Signalling Purinergic Signalling, 2020
Jiang-Fan Chen, R. Cunha
semanticscholar   +1 more source

Adenosine and Adenosine Enhancers in Treatment of Cardiovascular Diseases

, 2015
Adenosine, the endogenous purine, through its action on four adenosine receptors, is involved in various processes in the heart, such as regulation of the oxygen demand, decrease in sympathetic tone, cell pre-conditioning, inflammation and angiogenesis ...
Noori, Mohammad Saeid
core  

A computer generated model of adenosine receptors rationalising binding and selectivity of receptor ligands

, 1991
Computer graphic analyses on a broad spectrum of adenosine receptor ligands has shown that both the A1 and A2 adenosine receptors have three binding sites. The spatial relationship of these three binding sites has been defined.
Jayasuriya, Hiranthi, Quinn, Ronald J., Escher, Andre, Harden, Fiona, Dooley, Michael J.   +4 more
core   +1 more source

An Adenosine Receptor for Olfaction in Fish.

Current Biology, 2017
N. Wakisaka, Nobuhiko Miyasaka, T. Koide, Miwa Masuda, Towako Hiraki-Kajiyama, Y. Yoshihara   +5 more
semanticscholar   +1 more source